Gene name: TIF4632
Reference locus (S288C): YGL049C
Gene biotype: protein_coding
Description: Translation initiation factor eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); TIF4632 has a paralog, TIF4631, that arose from the whole genome duplication
Top 10 interactors (score): TIF1 (0.999); TIF2 (0.999); PAB1 (0.999); CDC33 (0.999); PRT1 (0.996); STO1 (0.993); RPG1 (0.992); TIF3 (0.992); CBC2 (0.99); NIP1 (0.986); TIF4631 (0.974); PUB1 (0.974); SUI2 (0.971); DED1 (0.968); YPK3 (0.961); SUI3 (0.961); TIF34 (0.954); TIF5 (0.954); DHH1 (0.952); TIF35 (0.942)
Homologues (species, bitscore): EIF4G3 (Homo sapiens, 144.1); Eif4g3 (Mus musculus, 144.1); eif4g3b (Danio rerio, 144.4); eif4g3 (Xenopus tropicalis, 143.7); eIF4G (Drosophila melanogaster, 125.9); ifg-1 (Caenorhabditis elegans, 91.7); EIF4G (Arabidopsis thaliana, 133.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:408935-411679:- | gene-YGL049C_AKU4011 | rna-NM_001180914.1_AKU4011 | cds-NP_011466.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:164450-167194:+ | gene-YGL049C_BG1 | rna-NM_001180914.1_BG1 | cds-NP_011466.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:409504-412248:- | gene-YGL049C_Bruggeman | rna-NM_001180914.1_Bruggeman | cds-NP_011466.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:407917-410661:- | gene-YGL049C_CAT1 | rna-NM_001180914.1_CAT1 | cds-NP_011466.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:410398-413142:- | gene-YGL049C_CBS1585 | rna-NM_001180914.1_CBS1585 | cds-NP_011466.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:404524-407268:- | gene-YGL049C_CBS436 | rna-NM_001180914.1_CBS436 | cds-NP_011466.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:402578-405322:- | gene-YGL049C_CBS6412 | rna-NM_001180914.1_CBS6412 | cds-NP_011466.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:406615-409359:- | gene-YGL049C_CBS6413 | rna-NM_001180914.1_CBS6413 | cds-NP_011466.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:406702-409446:- | gene-YGL049C_CENPK1137D | rna-NM_001180914.1_CENPK1137D | cds-NP_011466.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:397311-400055:- | gene-YGL049C_EthanolRed | rna-NM_001180914.1_EthanolRed | cds-NP_011466.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:400574-403318:- | gene-YGL049C_FaliES1 | rna-NM_001180914.1_FaliES1 | cds-NP_011466.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000165.1:13513-16257:+ | gene-YGL049C_JAY291 | rna-NM_001180914.1_JAY291 | cds-NP_011466.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:406708-409452:- | gene-YGL049C_MUCL30387 | rna-NM_001180914.1_MUCL30387 | cds-NP_011466.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:409755-412499:- | gene-YGL049C_MUCL30388 | rna-NM_001180914.1_MUCL30388 | cds-NP_011466.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:406191-408935:- | gene-YGL049C_MUCL39482 | rna-NM_001180914.1_MUCL39482 | cds-NP_011466.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:414608-417352:- | gene-YGL049C_MUCL42920 | rna-NM_001180914.1_MUCL42920 | cds-NP_011466.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:406860-409604:- | gene-YGL049C_NCIM3186 | rna-NM_001180914.1_NCIM3186 | cds-NP_011466.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:400316-403060:- | gene-YGL049C_NCYC1407 | rna-NM_001180914.1_NCYC1407 | cds-NP_011466.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:402889-405633:- | gene-YGL049C_PE2H3 | rna-NM_001180914.1_PE2H3 | cds-NP_011466.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:407939-410683:- | gene-YGL049C_PE2H4 | rna-NM_001180914.1_PE2H4 | cds-NP_011466.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:406860-409604:- | gene-YGL049C_S288C | rna-NM_001180914.1_S288C | cds-NP_011466.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:146024-148768:+ | gene-YGL049C_SA1 | rna-NM_001180914.1_SA1 | cds-NP_011466.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:419938-422682:- | gene-YGL049C_ThermosaccDry | rna-NM_001180914.1_ThermosaccDry | cds-NP_011466.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:509884-512628:- | gene-YGL049C_VR1 | rna-NM_001180914.1_VR1 | cds-NP_011466.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:398179-400923:- | gene-YGL049C_ZTW1 | rna-NM_001180914.1_ZTW1 | cds-NP_011466.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:407588-410332:- | gene-YGL049C_Sparadoxus | rna-NM_001180914.1_Sparadoxus | cds-NP_011466.1_Sparadoxus | 89.4 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |