Gene name: TIF4631
Reference locus (S288C): YGR162W
Gene biotype: protein_coding
Description: Translation initiation factor eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit; TIF4631 has a paralog, TIF4632, that arose from the whole genome duplication
Top 10 interactors (score): TIF2 (0.999); PAB1 (0.999); TIF1 (0.999); NIP1 (0.999); CDC33 (0.999); TIF3 (0.998); RPG1 (0.997); PRT1 (0.997); DED1 (0.996); STO1 (0.993); SUI2 (0.99); CBC2 (0.982); TIF5 (0.981); TIF4632 (0.974); GCD11 (0.969); HEK2 (0.964); SUI3 (0.962); YPK3 (0.961); PUB1 (0.958); RPA190 (0.957)
Homologues (species, bitscore): EIF4G3 (Homo sapiens, 138.7); Eif4g3 (Mus musculus, 140.2); eif4g3a (Danio rerio, 143.3); eif4g3 (Xenopus tropicalis, 139.4); NAT1 (Drosophila melanogaster, 128.3); ifg-1 (Caenorhabditis elegans, 92.4); EIF4G (Arabidopsis thaliana, 131.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:791808-794666:+ | gene-YGR162W_AKU4011 | rna-NM_001181291.3_AKU4011 | cds-NP_011678.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:69938-72796:+ | gene-YGR162W_BG1 | rna-NM_001181291.3_BG1 | cds-NP_011678.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:797739-800597:+ | gene-YGR162W_Bruggeman | rna-NM_001181291.3_Bruggeman | cds-NP_011678.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:793579-796449:+ | gene-YGR162W_CAT1 | rna-NM_001181291.3_CAT1 | cds-NP_011678.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:792524-795382:+ | gene-YGR162W_CBS1585 | rna-NM_001181291.3_CBS1585 | cds-NP_011678.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:796422-799280:+ | gene-YGR162W_CBS436 | rna-NM_001181291.3_CBS436 | cds-NP_011678.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:783893-786751:+ | gene-YGR162W_CBS6412 | rna-NM_001181291.3_CBS6412 | cds-NP_011678.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:789388-792246:+ | gene-YGR162W_CBS6413 | rna-NM_001181291.3_CBS6413 | cds-NP_011678.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:823794-826652:+ | gene-YGR162W_CENPK1137D | rna-NM_001181291.3_CENPK1137D | cds-NP_011678.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:777910-780768:+ | gene-YGR162W_EthanolRed | rna-NM_001181291.3_EthanolRed | cds-NP_011678.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:782300-785158:+ | gene-YGR162W_FaliES1 | rna-NM_001181291.3_FaliES1 | cds-NP_011678.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000112.1:24714-27572:+ | gene-YGR162W_JAY291 | rna-NM_001181291.3_JAY291 | cds-NP_011678.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:795230-798088:+ | gene-YGR162W_MUCL30387 | rna-NM_001181291.3_MUCL30387 | cds-NP_011678.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:794928-797786:+ | gene-YGR162W_MUCL30388 | rna-NM_001181291.3_MUCL30388 | cds-NP_011678.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:788099-790957:+ | gene-YGR162W_MUCL39482 | rna-NM_001181291.3_MUCL39482 | cds-NP_011678.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:803060-805918:+ | gene-YGR162W_MUCL42920 | rna-NM_001181291.3_MUCL42920 | cds-NP_011678.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:824059-826917:+ | gene-YGR162W_NCIM3186 | rna-NM_001181291.3_NCIM3186 | cds-NP_011678.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:783207-786065:+ | gene-YGR162W_NCYC1407 | rna-NM_001181291.3_NCYC1407 | cds-NP_011678.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:802407-805265:+ | gene-YGR162W_PE2H3 | rna-NM_001181291.3_PE2H3 | cds-NP_011678.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:807517-810375:+ | gene-YGR162W_PE2H4 | rna-NM_001181291.3_PE2H4 | cds-NP_011678.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:824059-826917:+ | gene-YGR162W_S288C | rna-NM_001181291.3_S288C | cds-NP_011678.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:47705-50563:+ | gene-YGR162W_SA1 | rna-NM_001181291.3_SA1 | cds-NP_011678.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:802811-805669:+ | gene-YGR162W_ThermosaccDry | rna-NM_001181291.3_ThermosaccDry | cds-NP_011678.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:907557-910415:+ | gene-YGR162W_VR1 | rna-NM_001181291.3_VR1 | cds-NP_011678.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:104744-107602:+ | gene-YGR162W_ZTW1 | rna-NM_001181291.3_ZTW1 | cds-NP_011678.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:794039-796891:- | gene-YGR162W_Sparadoxus | rna-NM_001181291.3_Sparadoxus | cds-NP_011678.3_Sparadoxus | 91.0 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |