Gene name: TIF3
Reference locus (S288C): YPR163C
Gene biotype: protein_coding
Description: Translation initiation factor eIF-4B; contains an RNA recognition motif and binds to single-stranded RNA; has RNA annealing activity; interacts with Rps20p at the head of the 40S ribosomal subunit and alters the structure of the mRNA entry channel
Top 10 interactors (score): CDC33 (0.999); RPG1 (0.999); TIF1 (0.999); TIF2 (0.999); TIF4631 (0.998); TIF35 (0.997); PAB1 (0.995); FUN12 (0.992); TIF4632 (0.992); RPA135 (0.982); NOG1 (0.981); TIF5 (0.975); HAS1 (0.973); RPS3 (0.964); CBF5 (0.963); PRT1 (0.96); SUP35 (0.954); DED1 (0.948); NUG1 (0.947); FAL1 (0.939)
Homologues (species, bitscore): EIF4B (Homo sapiens, 58.2); Eif4b (Mus musculus, 55.8); eif4h (Danio rerio, 57.0); eif4b (Xenopus tropicalis, 55.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:822921-824231:- | gene-YPR163C_AKU4011 | rna-NM_001184260.1_AKU4011 | cds-NP_015489.1_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:73485-74795:+ | gene-YPR163C_BG1 | rna-NM_001184260.1_BG1 | cds-NP_015489.1_BG1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:903113-904423:- | gene-YPR163C_Bruggeman | rna-NM_001184260.1_Bruggeman | cds-NP_015489.1_Bruggeman | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:945720-947030:- | gene-YPR163C_CAT1 | rna-NM_001184260.1_CAT1 | cds-NP_015489.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:827721-829031:- | gene-YPR163C_CBS1585 | rna-NM_001184260.1_CBS1585 | cds-NP_015489.1_CBS1585 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:841277-842587:- | gene-YPR163C_CBS436 | rna-NM_001184260.1_CBS436 | cds-NP_015489.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:829585-830817:- | gene-YPR163C_CBS6412 | rna-NM_001184260.1_CBS6412 | cds-NP_015489.1_CBS6412 | 92.9 | 94.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:824651-825961:- | gene-YPR163C_CBS6413 | rna-NM_001184260.1_CBS6413 | cds-NP_015489.1_CBS6413 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:868656-870004:- | gene-YPR163C_CENPK1137D | rna-NM_001184260.1_CENPK1137D | cds-NP_015489.1_CENPK1137D | 94.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1144555-1145865:- | gene-YPR163C_EthanolRed | rna-NM_001184260.1_EthanolRed | cds-NP_015489.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:824261-825571:- | gene-YPR163C_FaliES1 | rna-NM_001184260.1_FaliES1 | cds-NP_015489.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000081.1:12053-13363:- | gene-YPR163C_JAY291 | rna-NM_001184260.1_JAY291 | cds-NP_015489.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:871198-872508:- | gene-YPR163C_MUCL30387 | rna-NM_001184260.1_MUCL30387 | cds-NP_015489.1_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:843776-845335:- | gene-YPR163C_MUCL30388 | rna-NM_001184260.1_MUCL30388 | cds-NP_015489.1_MUCL30388 | 83.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:819923-821233:- | gene-YPR163C_MUCL39482 | rna-NM_001184260.1_MUCL39482 | cds-NP_015489.1_MUCL39482 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:883585-884895:- | gene-YPR163C_MUCL42920 | rna-NM_001184260.1_MUCL42920 | cds-NP_015489.1_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:868628-869938:- | gene-YPR163C_NCIM3186 | rna-NM_001184260.1_NCIM3186 | cds-NP_015489.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:828284-829594:- | gene-YPR163C_NCYC1407 | rna-NM_001184260.1_NCYC1407 | cds-NP_015489.1_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:840577-841887:- | gene-YPR163C_PE2H3 | rna-NM_001184260.1_PE2H3 | cds-NP_015489.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:840225-841535:- | gene-YPR163C_PE2H4 | rna-NM_001184260.1_PE2H4 | cds-NP_015489.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:868645-869955:- | gene-YPR163C_S288C | rna-NM_001184260.1_S288C | cds-NP_015489.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:56205-57515:+ | gene-YPR163C_SA1 | rna-NM_001184260.1_SA1 | cds-NP_015489.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:823949-825259:- | gene-YPR163C_ThermosaccDry | rna-NM_001184260.1_ThermosaccDry | cds-NP_015489.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:852232-853542:- | gene-YPR163C_VR1 | rna-NM_001184260.1_VR1 | cds-NP_015489.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:827071-828303:- | gene-YPR163C_ZTW1 | rna-NM_001184260.1_ZTW1 | cds-NP_015489.1_ZTW1 | 93.1 | 94.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:829140-830450:- | gene-YPR163C_Sparadoxus | rna-NM_001184260.1_Sparadoxus | cds-NP_015489.1_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |