THR4 (YCR053W)


Gene profile

Gene name: THR4
Reference locus (S288C): YCR053W
Gene biotype: protein_coding

Description: Threonine synthase; conserved protein that catalyzes formation of threonine from O-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway

Top 10 interactors (score): THR1 (0.999); HOM3 (0.997); HOM6 (0.997); HOM2 (0.997); PRO3 (0.995); TYR1 (0.994); SER2 (0.991); TRP5 (0.99); SSU72 (0.976); SER1 (0.974); ILV1 (0.974); CHA1 (0.973); GLY1 (0.95); RTT103 (0.918); FCP1 (0.918); RPO21 (0.907); ESS1 (0.896); PCF11 (0.886); SPT5 (0.874); KIN28 (0.868)

Homologues (species, bitscore): THNSL2 (Homo sapiens, 308.5); Thnsl2 (Mus musculus, 313.9); thnsl2 (Danio rerio, 276.9); thnsl2 (Xenopus tropicalis, 305.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:211155-212699:+ gene-YCR053W_AKU4011 rna-NM_001178767.1_AKU4011 cds-NP_009982.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000067.1:65358-66902:+ gene-YCR053W_BG1 rna-NM_001178767.1_BG1 cds-NP_009982.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:207115-208659:+ gene-YCR053W_Bruggeman rna-NM_001178767.1_Bruggeman cds-NP_009982.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:218488-220032:+ gene-YCR053W_CAT1 rna-NM_001178767.1_CAT1 cds-NP_009982.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:205933-207477:+ gene-YCR053W_CBS1585 rna-NM_001178767.1_CBS1585 cds-NP_009982.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:217829-219373:+ gene-YCR053W_CBS436 rna-NM_001178767.1_CBS436 cds-NP_009982.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:197673-199217:+ gene-YCR053W_CBS6412 rna-NM_001178767.1_CBS6412 cds-NP_009982.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:212050-213594:+ gene-YCR053W_CBS6413 rna-NM_001178767.1_CBS6413 cds-NP_009982.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:215879-217423:+ gene-YCR053W_CENPK1137D rna-NM_001178767.1_CENPK1137D cds-NP_009982.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:207118-208662:+ gene-YCR053W_EthanolRed rna-NM_001178767.1_EthanolRed cds-NP_009982.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:212283-213827:+ gene-YCR053W_FaliES1 rna-NM_001178767.1_FaliES1 cds-NP_009982.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000014.1:9353-10897:- gene-YCR053W_JAY291 rna-NM_001178767.1_JAY291 cds-NP_009982.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:204099-205643:+ gene-YCR053W_MUCL30387 rna-NM_001178767.1_MUCL30387 cds-NP_009982.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:203473-205017:+ gene-YCR053W_MUCL30388 rna-NM_001178767.1_MUCL30388 cds-NP_009982.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:212506-214050:+ gene-YCR053W_MUCL39482 rna-NM_001178767.1_MUCL39482 cds-NP_009982.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:208948-210492:+ gene-YCR053W_MUCL42920 rna-NM_001178767.1_MUCL42920 cds-NP_009982.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:216329-217873:+ gene-YCR053W_NCIM3186 rna-NM_001178767.1_NCIM3186 cds-NP_009982.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:213365-214909:+ gene-YCR053W_NCYC1407 rna-NM_001178767.1_NCYC1407 cds-NP_009982.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:222043-223587:+ gene-YCR053W_PE2H3 rna-NM_001178767.1_PE2H3 cds-NP_009982.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:216569-218113:+ gene-YCR053W_PE2H4 rna-NM_001178767.1_PE2H4 cds-NP_009982.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:216697-218241:+ gene-YCR053W_S288C rna-NM_001178767.1_S288C cds-NP_009982.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000044.1:16580-18124:+ gene-YCR053W_SA1 rna-NM_001178767.1_SA1 cds-NP_009982.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:212266-213810:+ gene-YCR053W_ThermosaccDry rna-NM_001178767.1_ThermosaccDry cds-NP_009982.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:223541-225085:+ gene-YCR053W_VR1 rna-NM_001178767.1_VR1 cds-NP_009982.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:210089-211633:+ gene-YCR053W_ZTW1 rna-NM_001178767.1_ZTW1 cds-NP_009982.1_ZTW1 99.3 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:244248-245792:+ gene-YCR053W_Sparadoxus rna-NM_001178767.1_Sparadoxus cds-NP_009982.1_Sparadoxus 92.2 100.0 Verified 1 1 1 False True False False False

Additional files