THR1 (YHR025W)


Gene profile

Gene name: THR1
Reference locus (S288C): YHR025W
Gene biotype: protein_coding

Description: Homoserine kinase; conserved protein required for threonine biosynthesis; long-lived protein that is preferentially retained in mother cells and forms cytoplasmic filaments; expression is regulated by the GCN4-mediated general amino acid control pathway

Top 10 interactors (score): THR4 (0.999); HOM6 (0.999); HOM3 (0.999); HOM2 (0.997); STR2 (0.951); MET6 (0.925); CHA1 (0.923); SAM4 (0.92); DED81 (0.909); CYS3 (0.901); YML082W (0.898); BAT1 (0.895); CYS4 (0.891); BAT2 (0.885); STR3 (0.871); MHT1 (0.863); IRC7 (0.858); YLL058W (0.858); TRP5 (0.855); ILV1 (0.841)

Homologues (species, bitscore): HSK (Arabidopsis thaliana, 88.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:147636-148709:+ gene-YHR025W_AKU4011 rna-NM_001179155.1_AKU4011 cds-NP_011890.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:67922-68995:+ gene-YHR025W_BG1 rna-NM_001179155.1_BG1 cds-NP_011890.1_BG1 99.3 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:155160-156233:+ gene-YHR025W_Bruggeman rna-NM_001179155.1_Bruggeman cds-NP_011890.1_Bruggeman 99.4 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:149541-150614:+ gene-YHR025W_CAT1 rna-NM_001179155.1_CAT1 cds-NP_011890.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:147968-149041:+ gene-YHR025W_CBS1585 rna-NM_001179155.1_CBS1585 cds-NP_011890.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:142313-143386:+ gene-YHR025W_CBS436 rna-NM_001179155.1_CBS436 cds-NP_011890.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:147660-148733:+ gene-YHR025W_CBS6412 rna-NM_001179155.1_CBS6412 cds-NP_011890.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:147792-148865:+ gene-YHR025W_CBS6413 rna-NM_001179155.1_CBS6413 cds-NP_011890.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:152707-153780:+ gene-YHR025W_CENPK1137D rna-NM_001179155.1_CENPK1137D cds-NP_011890.1_CENPK1137D 99.4 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:147181-148254:+ gene-YHR025W_EthanolRed rna-NM_001179155.1_EthanolRed cds-NP_011890.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:148160-149233:+ gene-YHR025W_FaliES1 rna-NM_001179155.1_FaliES1 cds-NP_011890.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000273.1:32374-33447:- gene-YHR025W_JAY291 rna-NM_001179155.1_JAY291 cds-NP_011890.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:154229-155302:+ gene-YHR025W_MUCL30387 rna-NM_001179155.1_MUCL30387 cds-NP_011890.1_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:154701-155774:+ gene-YHR025W_MUCL30388 rna-NM_001179155.1_MUCL30388 cds-NP_011890.1_MUCL30388 99.3 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:146995-148068:+ gene-YHR025W_MUCL39482 rna-NM_001179155.1_MUCL39482 cds-NP_011890.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:153772-154845:+ gene-YHR025W_MUCL42920 rna-NM_001179155.1_MUCL42920 cds-NP_011890.1_MUCL42920 99.4 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:159320-160393:+ gene-YHR025W_NCIM3186 rna-NM_001179155.1_NCIM3186 cds-NP_011890.1_NCIM3186 99.2 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:146907-147980:+ gene-YHR025W_NCYC1407 rna-NM_001179155.1_NCYC1407 cds-NP_011890.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:149318-150391:+ gene-YHR025W_PE2H3 rna-NM_001179155.1_PE2H3 cds-NP_011890.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:156759-157832:+ gene-YHR025W_PE2H4 rna-NM_001179155.1_PE2H4 cds-NP_011890.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:159438-160511:+ gene-YHR025W_S288C rna-NM_001179155.1_S288C cds-NP_011890.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000106.1:12983-14056:+ gene-YHR025W_SA1 rna-NM_001179155.1_SA1 cds-NP_011890.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:149249-150322:+ gene-YHR025W_ThermosaccDry rna-NM_001179155.1_ThermosaccDry cds-NP_011890.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:155789-156862:+ gene-YHR025W_VR1 rna-NM_001179155.1_VR1 cds-NP_011890.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:140840-141913:+ gene-YHR025W_ZTW1 rna-NM_001179155.1_ZTW1 cds-NP_011890.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:146966-148039:+ gene-YHR025W_Sparadoxus rna-NM_001179155.1_Sparadoxus cds-NP_011890.1_Sparadoxus 92.7 100.0 Verified 1 1 1 False True False False False

Additional files