THP3 (YPR045C)


Gene profile

Gene name: THP3
Reference locus (S288C): YPR045C
Gene biotype: protein_coding

Description: SAC3 family protein LENG8/THP3; Protein that may have a role in transcription elongation; forms a complex with Csn12p that is recruited to transcribed genes; possibly involved in splicing based on pre-mRNA accumulation defect for many intron-containing genes

Top 10 interactors (score): YJR084W (0.997); SEM1 (0.777); YLR177W (0.771); KEL3 (0.768); RPN3 (0.754); CSN9 (0.744); KCH1 (0.714); SYH1 (0.709); OPI11 (0.699); RPN12 (0.698); UFD4 (0.644); PCI8 (0.618); YPR174C (0.617); YPL150W (0.617); FIP1 (0.605); SAC1 (0.595); PUS9 (0.579); YEL043W (0.571); NNF2 (0.568); RRI2 (0.558)

Homologues (species, bitscore): LENG8 (Homo sapiens, 151.0); Leng8 (Mus musculus, 144.8); LENG8 (Danio rerio, 160.6); leng8 (Xenopus tropicalis, 150.6); CG6700 (Drosophila melanogaster, 147.5); hpo-10 (Caenorhabditis elegans, 137.5); SAC3A (Arabidopsis thaliana, 136.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:626807-628219:- gene-YPR045C_AKU4011 rna-NM_001184142.1_AKU4011 cds-NP_015370.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:269461-270873:+ gene-YPR045C_BG1 rna-NM_001184142.1_BG1 cds-NP_015370.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:704475-705887:- gene-YPR045C_Bruggeman rna-NM_001184142.1_Bruggeman cds-NP_015370.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:747929-749341:- gene-YPR045C_CAT1 rna-NM_001184142.1_CAT1 cds-NP_015370.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:630493-631905:- gene-YPR045C_CBS1585 rna-NM_001184142.1_CBS1585 cds-NP_015370.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:644871-646283:- gene-YPR045C_CBS436 rna-NM_001184142.1_CBS436 cds-NP_015370.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:634241-635653:- gene-YPR045C_CBS6412 rna-NM_001184142.1_CBS6412 cds-NP_015370.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:627442-628854:- gene-YPR045C_CBS6413 rna-NM_001184142.1_CBS6413 cds-NP_015370.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:655107-656519:- gene-YPR045C_CENPK1137D rna-NM_001184142.1_CENPK1137D cds-NP_015370.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:953997-955409:- gene-YPR045C_EthanolRed rna-NM_001184142.1_EthanolRed cds-NP_015370.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:632634-634046:- gene-YPR045C_FaliES1 rna-NM_001184142.1_FaliES1 cds-NP_015370.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000446.1:4592-6004:- gene-YPR045C_JAY291 rna-NM_001184142.1_JAY291 cds-NP_015370.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:645736-647148:- gene-YPR045C_MUCL30387 rna-NM_001184142.1_MUCL30387 cds-NP_015370.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:644440-645852:- gene-YPR045C_MUCL30388 rna-NM_001184142.1_MUCL30388 cds-NP_015370.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:623750-625162:- gene-YPR045C_MUCL39482 rna-NM_001184142.1_MUCL39482 cds-NP_015370.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:686577-687989:- gene-YPR045C_MUCL42920 rna-NM_001184142.1_MUCL42920 cds-NP_015370.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:655123-656535:- gene-YPR045C_NCIM3186 rna-NM_001184142.1_NCIM3186 cds-NP_015370.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:631680-633092:- gene-YPR045C_NCYC1407 rna-NM_001184142.1_NCYC1407 cds-NP_015370.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:637895-639307:- gene-YPR045C_PE2H3 rna-NM_001184142.1_PE2H3 cds-NP_015370.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:637543-638955:- gene-YPR045C_PE2H4 rna-NM_001184142.1_PE2H4 cds-NP_015370.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:655140-656552:- gene-YPR045C_S288C rna-NM_001184142.1_S288C cds-NP_015370.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:44138-45550:+ gene-YPR045C_SA1 rna-NM_001184142.1_SA1 cds-NP_015370.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:632409-633821:- gene-YPR045C_ThermosaccDry rna-NM_001184142.1_ThermosaccDry cds-NP_015370.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:648568-649980:- gene-YPR045C_VR1 rna-NM_001184142.1_VR1 cds-NP_015370.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:631641-633053:- gene-YPR045C_ZTW1 rna-NM_001184142.1_ZTW1 cds-NP_015370.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:632407-633819:- gene-YPR045C_Sparadoxus rna-NM_001184142.1_Sparadoxus cds-NP_015370.1_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files