Gene name: THP1
Reference locus (S288C): YOL072W
Gene biotype: protein_coding
Description: Nuclear mRNA export protein THP1; Nuclear pore-associated protein; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; contains a PAM domain implicated in protein-protein binding
Top 10 interactors (score): SEM1 (0.999); SAC3 (0.999); CDC31 (0.999); SUS1 (0.995); YJR084W (0.92); MEX67 (0.854); YOL057W (0.76); PTH4 (0.75); DBP5 (0.732); RRI2 (0.715); RBA50 (0.715); NEM1 (0.696); SWR1 (0.671); MSB4 (0.658); SUB2 (0.635); MDY2 (0.618); GLE2 (0.615); VPS71 (0.613); CDC73 (0.611); YRA1 (0.592)
Homologues (species, bitscore): PCID2 (Homo sapiens, 68.2); Pcid2 (Mus musculus, 70.5); pcid2 (Danio rerio, 73.2); pcid2 (Xenopus tropicalis, 67.8); PCID2 (Drosophila melanogaster, 60.5); C27F2.10 (Caenorhabditis elegans, 67.0); EER5 (Arabidopsis thaliana, 54.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:178613-179980:+ | gene-YOL072W_AKU4011 | rna-NM_001183327.1_AKU4011 | cds-NP_014569.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:143418-144785:+ | gene-YOL072W_BG1 | rna-NM_001183327.1_BG1 | cds-NP_014569.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:180296-181663:+ | gene-YOL072W_Bruggeman | rna-NM_001183327.1_Bruggeman | cds-NP_014569.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:179792-181159:+ | gene-YOL072W_CAT1 | rna-NM_001183327.1_CAT1 | cds-NP_014569.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:173006-174373:+ | gene-YOL072W_CBS1585 | rna-NM_001183327.1_CBS1585 | cds-NP_014569.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:178185-179552:+ | gene-YOL072W_CBS436 | rna-NM_001183327.1_CBS436 | cds-NP_014569.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:172934-174301:+ | gene-YOL072W_CBS6412 | rna-NM_001183327.1_CBS6412 | cds-NP_014569.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:179869-181236:+ | gene-YOL072W_CBS6413 | rna-NM_001183327.1_CBS6413 | cds-NP_014569.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:194722-196089:+ | gene-YOL072W_CENPK1137D | rna-NM_001183327.1_CENPK1137D | cds-NP_014569.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:175927-177294:+ | gene-YOL072W_EthanolRed | rna-NM_001183327.1_EthanolRed | cds-NP_014569.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:178254-179621:+ | gene-YOL072W_FaliES1 | rna-NM_001183327.1_FaliES1 | cds-NP_014569.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:85920-87287:- | gene-YOL072W_JAY291 | rna-NM_001183327.1_JAY291 | cds-NP_014569.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:184066-185433:+ | gene-YOL072W_MUCL30387 | rna-NM_001183327.1_MUCL30387 | cds-NP_014569.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:187745-189112:+ | gene-YOL072W_MUCL30388 | rna-NM_001183327.1_MUCL30388 | cds-NP_014569.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:180927-182294:+ | gene-YOL072W_MUCL39482 | rna-NM_001183327.1_MUCL39482 | cds-NP_014569.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:196418-197785:+ | gene-YOL072W_MUCL42920 | rna-NM_001183327.1_MUCL42920 | cds-NP_014569.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:194859-196226:+ | gene-YOL072W_NCIM3186 | rna-NM_001183327.1_NCIM3186 | cds-NP_014569.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:187547-188914:+ | gene-YOL072W_NCYC1407 | rna-NM_001183327.1_NCYC1407 | cds-NP_014569.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:170538-171905:+ | gene-YOL072W_PE2H3 | rna-NM_001183327.1_PE2H3 | cds-NP_014569.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:181528-182895:+ | gene-YOL072W_PE2H4 | rna-NM_001183327.1_PE2H4 | cds-NP_014569.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:194970-196337:+ | gene-YOL072W_S288C | rna-NM_001183327.1_S288C | cds-NP_014569.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:162852-164219:+ | gene-YOL072W_SA1 | rna-NM_001183327.1_SA1 | cds-NP_014569.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:177262-178629:+ | gene-YOL072W_ThermosaccDry | rna-NM_001183327.1_ThermosaccDry | cds-NP_014569.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:178038-179405:+ | gene-YOL072W_VR1 | rna-NM_001183327.1_VR1 | cds-NP_014569.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:176924-178291:+ | gene-YOL072W_ZTW1 | rna-NM_001183327.1_ZTW1 | cds-NP_014569.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:180487-181854:+ | gene-YOL072W_Sparadoxus | rna-NM_001183327.1_Sparadoxus | cds-NP_014569.1_Sparadoxus | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |