Gene name: THO2
Reference locus (S288C): YNL139C
Gene biotype: protein_coding
Description: Subunit of the THO complex; THO is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids; Belongs to the THOC2 family
Top 10 interactors (score): MFT1 (0.999); YRA1 (0.999); SUB2 (0.999); HPR1 (0.999); THP2 (0.999); TEX1 (0.996); SAC3 (0.995); STO1 (0.975); GBP2 (0.971); MEX67 (0.957); HRB1 (0.945); PCF11 (0.931); CTR9 (0.918); CBC2 (0.912); SCC2 (0.901); NUP159 (0.897); MLP1 (0.885); NAB2 (0.882); CDC31 (0.874); NPL3 (0.834)
Homologues (species, bitscore): THOC2 (Homo sapiens, 177.6); Thoc2 (Mus musculus, 176.4); thoc2 (Danio rerio, 169.5); thoc2 (Xenopus tropicalis, 165.6); tho2 (Drosophila melanogaster, 149.1); thoc-2 (Caenorhabditis elegans, 147.9); THO2 (Arabidopsis thaliana, 227.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:354609-359402:- | gene-YNL139C_AKU4011 | rna-NM_001182977.3_AKU4011 | cds-NP_014260.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:258601-263394:- | gene-YNL139C_BG1 | rna-NM_001182977.3_BG1 | cds-NP_014260.3_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:364706-369499:- | gene-YNL139C_Bruggeman | rna-NM_001182977.3_Bruggeman | cds-NP_014260.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:407600-412695:- | gene-YNL139C_CAT1 | rna-NM_001182977.3_CAT1 | cds-NP_014260.3_CAT1 | 93.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:355228-360021:- | gene-YNL139C_CBS1585 | rna-NM_001182977.3_CBS1585 | cds-NP_014260.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:423623-428416:- | gene-YNL139C_CBS436 | rna-NM_001182977.3_CBS436 | cds-NP_014260.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:350682-355475:- | gene-YNL139C_CBS6412 | rna-NM_001182977.3_CBS6412 | cds-NP_014260.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:351646-356439:- | gene-YNL139C_CBS6413 | rna-NM_001182977.3_CBS6413 | cds-NP_014260.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:354776-359569:- | gene-YNL139C_CENPK1137D | rna-NM_001182977.3_CENPK1137D | cds-NP_014260.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:351600-356393:- | gene-YNL139C_EthanolRed | rna-NM_001182977.3_EthanolRed | cds-NP_014260.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:347502-352295:- | gene-YNL139C_FaliES1 | rna-NM_001182977.3_FaliES1 | cds-NP_014260.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:3882-8675:- | gene-YNL139C_JAY291 | rna-NM_001182977.3_JAY291 | cds-NP_014260.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:360721-365514:- | gene-YNL139C_MUCL30387 | rna-NM_001182977.3_MUCL30387 | cds-NP_014260.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:395838-400631:- | gene-YNL139C_MUCL30388 | rna-NM_001182977.3_MUCL30388 | cds-NP_014260.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:352508-357301:- | gene-YNL139C_MUCL39482 | rna-NM_001182977.3_MUCL39482 | cds-NP_014260.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:355503-360296:- | gene-YNL139C_MUCL42920 | rna-NM_001182977.3_MUCL42920 | cds-NP_014260.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:360893-365686:- | gene-YNL139C_NCIM3186 | rna-NM_001182977.3_NCIM3186 | cds-NP_014260.3_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:354640-359433:- | gene-YNL139C_NCYC1407 | rna-NM_001182977.3_NCYC1407 | cds-NP_014260.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:351639-356432:- | gene-YNL139C_PE2H3 | rna-NM_001182977.3_PE2H3 | cds-NP_014260.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:351027-355820:- | gene-YNL139C_PE2H4 | rna-NM_001182977.3_PE2H4 | cds-NP_014260.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:360924-365717:- | gene-YNL139C_S288C | rna-NM_001182977.3_S288C | cds-NP_014260.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:47796-52589:+ | gene-YNL139C_SA1 | rna-NM_001182977.3_SA1 | cds-NP_014260.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:348356-353149:- | gene-YNL139C_ThermosaccDry | rna-NM_001182977.3_ThermosaccDry | cds-NP_014260.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:367019-371812:- | gene-YNL139C_VR1 | rna-NM_001182977.3_VR1 | cds-NP_014260.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:258190-262983:- | gene-YNL139C_ZTW1 | rna-NM_001182977.3_ZTW1 | cds-NP_014260.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:359148-363941:- | gene-YNL139C_Sparadoxus | rna-NM_001182977.3_Sparadoxus | cds-NP_014260.3_Sparadoxus | 88.7 | 99.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |