THO1 (YER063W)


Gene profile

Gene name: THO1
Reference locus (S288C): YER063W
Gene biotype: protein_coding

Description: Sap domain-containing ribonucleoprotein; Protein THO1; Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation

Top 10 interactors (score): SUB2 (0.849); YRA1 (0.82); HPR1 (0.807); THO2 (0.769); YGR126W (0.711); YOR062C (0.695); NAB2 (0.691); YOR333C (0.687); YHR210C (0.676); YJR120W (0.671); ECM23 (0.671); THP2 (0.67); SAC3 (0.661); PAU7 (0.611); YBL029C-A (0.574); BCH1 (0.573); YDR154C (0.571); CRP1 (0.571); YJL015C (0.571); NNR2 (0.563)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:275504-276160:+ gene-YER063W_AKU4011 rna-NM_001178954.1_AKU4011 cds-NP_010985.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:149615-150271:- gene-YER063W_BG1 rna-NM_001178954.1_BG1 cds-NP_010985.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:284816-285472:+ gene-YER063W_Bruggeman rna-NM_001178954.1_Bruggeman cds-NP_010985.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:278459-279115:+ gene-YER063W_CAT1 rna-NM_001178954.1_CAT1 cds-NP_010985.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:275360-276016:+ gene-YER063W_CBS1585 rna-NM_001178954.1_CBS1585 cds-NP_010985.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:277270-277926:+ gene-YER063W_CBS436 rna-NM_001178954.1_CBS436 cds-NP_010985.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:274830-275486:+ gene-YER063W_CBS6412 rna-NM_001178954.1_CBS6412 cds-NP_010985.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:280836-281492:+ gene-YER063W_CBS6413 rna-NM_001178954.1_CBS6413 cds-NP_010985.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:279560-280216:+ gene-YER063W_CENPK1137D rna-NM_001178954.1_CENPK1137D cds-NP_010985.1_CENPK1137D 99.5 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:275844-276500:+ gene-YER063W_EthanolRed rna-NM_001178954.1_EthanolRed cds-NP_010985.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:276297-276953:+ gene-YER063W_FaliES1 rna-NM_001178954.1_FaliES1 cds-NP_010985.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000254.1:3716-4372:+ gene-YER063W_JAY291 rna-NM_001178954.1_JAY291 cds-NP_010985.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:280253-280909:+ gene-YER063W_MUCL30387 rna-NM_001178954.1_MUCL30387 cds-NP_010985.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:275923-276579:+ gene-YER063W_MUCL30388 rna-NM_001178954.1_MUCL30388 cds-NP_010985.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:274395-275051:+ gene-YER063W_MUCL39482 rna-NM_001178954.1_MUCL39482 cds-NP_010985.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:281451-282107:+ gene-YER063W_MUCL42920 rna-NM_001178954.1_MUCL42920 cds-NP_010985.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:281709-282365:+ gene-YER063W_NCIM3186 rna-NM_001178954.1_NCIM3186 cds-NP_010985.1_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:279458-280114:+ gene-YER063W_NCYC1407 rna-NM_001178954.1_NCYC1407 cds-NP_010985.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:290111-290767:+ gene-YER063W_PE2H3 rna-NM_001178954.1_PE2H3 cds-NP_010985.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:280052-280708:+ gene-YER063W_PE2H4 rna-NM_001178954.1_PE2H4 cds-NP_010985.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:281710-282366:+ gene-YER063W_S288C rna-NM_001178954.1_S288C cds-NP_010985.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000059.1:68229-68885:+ gene-YER063W_SA1 rna-NM_001178954.1_SA1 cds-NP_010985.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:277093-277749:+ gene-YER063W_ThermosaccDry rna-NM_001178954.1_ThermosaccDry cds-NP_010985.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:276794-277450:+ gene-YER063W_VR1 rna-NM_001178954.1_VR1 cds-NP_010985.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:274273-274929:+ gene-YER063W_ZTW1 rna-NM_001178954.1_ZTW1 cds-NP_010985.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:278216-278866:+ gene-YER063W_Sparadoxus rna-NM_001178954.1_Sparadoxus cds-NP_010985.1_Sparadoxus 84.8 98.4 Verified 1 1 1 False True False False False

Additional files