Gene name: THI74
Reference locus (S288C): YDR438W
Gene biotype: protein_coding
Description: Mitochondrial transporter repressible by thiamine; THI74 has a paralog, YML018C, that arose from the whole genome duplication; shows sequence homology to human gene SLC35F3, a thiamine transporter implicated in hypertension
Top 10 interactors (score): HUT1 (0.908); YEA4 (0.783); TPN1 (0.78); YMD8 (0.771); THI12 (0.771); HVG1 (0.77); MCH5 (0.726); THI7 (0.718); THI11 (0.713); AAD14 (0.713); THI5 (0.712); THI13 (0.712); PDC2 (0.699); PET18 (0.679); THI2 (0.672); VRG4 (0.633); YDR541C (0.63); THI3 (0.62); LEU5 (0.508); PDC5 (0.454)
Homologues (species, bitscore): SLC35F5 (Homo sapiens, 149.4); Slc35f5 (Mus musculus, 154.1); slc35f5 (Xenopus tropicalis, 83.6); CG8195 (Drosophila melanogaster, 132.1); B0041.5 (Caenorhabditis elegans, 81.3); AT4G32140 (Arabidopsis thaliana, 161.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1278547-1279659:+ | gene-YDR438W_AKU4011 | rna-NM_001180746.3_AKU4011 | cds-NP_010726.3_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:156883-157995:+ | gene-YDR438W_BG1 | rna-NM_001180746.3_BG1 | cds-NP_010726.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1308930-1310042:+ | gene-YDR438W_Bruggeman | rna-NM_001180746.3_Bruggeman | cds-NP_010726.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1287120-1288232:+ | gene-YDR438W_CAT1 | rna-NM_001180746.3_CAT1 | cds-NP_010726.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1272854-1273966:+ | gene-YDR438W_CBS1585 | rna-NM_001180746.3_CBS1585 | cds-NP_010726.3_CBS1585 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1292204-1293316:+ | gene-YDR438W_CBS436 | rna-NM_001180746.3_CBS436 | cds-NP_010726.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1268492-1269604:+ | gene-YDR438W_CBS6412 | rna-NM_001180746.3_CBS6412 | cds-NP_010726.3_CBS6412 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1291006-1292118:+ | gene-YDR438W_CBS6413 | rna-NM_001180746.3_CBS6413 | cds-NP_010726.3_CBS6413 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1336952-1338064:+ | gene-YDR438W_CENPK1137D | rna-NM_001180746.3_CENPK1137D | cds-NP_010726.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1281917-1283029:+ | gene-YDR438W_EthanolRed | rna-NM_001180746.3_EthanolRed | cds-NP_010726.3_EthanolRed | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1285468-1286580:+ | gene-YDR438W_FaliES1 | rna-NM_001180746.3_FaliES1 | cds-NP_010726.3_FaliES1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000263.1:29687-30799:+ | gene-YDR438W_JAY291 | rna-NM_001180746.3_JAY291 | cds-NP_010726.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1292572-1293684:+ | gene-YDR438W_MUCL30387 | rna-NM_001180746.3_MUCL30387 | cds-NP_010726.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1274506-1275618:+ | gene-YDR438W_MUCL30388 | rna-NM_001180746.3_MUCL30388 | cds-NP_010726.3_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1264345-1265457:+ | gene-YDR438W_MUCL39482 | rna-NM_001180746.3_MUCL39482 | cds-NP_010726.3_MUCL39482 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1206764-1207876:+ | gene-YDR438W_MUCL42920 | rna-NM_001180746.3_MUCL42920 | cds-NP_010726.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1338197-1339309:+ | gene-YDR438W_NCIM3186 | rna-NM_001180746.3_NCIM3186 | cds-NP_010726.3_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1278110-1279222:+ | gene-YDR438W_NCYC1407 | rna-NM_001180746.3_NCYC1407 | cds-NP_010726.3_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1288930-1290042:+ | gene-YDR438W_PE2H3 | rna-NM_001180746.3_PE2H3 | cds-NP_010726.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1294498-1295610:+ | gene-YDR438W_PE2H4 | rna-NM_001180746.3_PE2H4 | cds-NP_010726.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1338274-1339386:+ | gene-YDR438W_S288C | rna-NM_001180746.3_S288C | cds-NP_010726.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000082.1:17830-18942:- | gene-YDR438W_SA1 | rna-NM_001180746.3_SA1 | cds-NP_010726.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1289692-1290804:+ | gene-YDR438W_ThermosaccDry | rna-NM_001180746.3_ThermosaccDry | cds-NP_010726.3_ThermosaccDry | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1304911-1306023:+ | gene-YDR438W_VR1 | rna-NM_001180746.3_VR1 | cds-NP_010726.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:332328-333440:+ | gene-YDR438W_ZTW1 | rna-NM_001180746.3_ZTW1 | cds-NP_010726.3_ZTW1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1286077-1287189:+ | gene-YDR438W_Sparadoxus | rna-NM_001180746.3_Sparadoxus | cds-NP_010726.3_Sparadoxus | 88.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |