THI7 (YLR237W)


Gene profile

Gene name: THI7
Reference locus (S288C): YLR237W
Gene biotype: protein_coding

Description: Nucleobase:cation symporter-1, ncs1 family; Plasma membrane transporter responsible for the uptake of thiamine; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia

Top 10 interactors (score): THI4 (0.861); THI20 (0.859); THI11 (0.842); THI6 (0.825); THI3 (0.777); THI21 (0.769); THI5 (0.766); PDC2 (0.749); THI12 (0.746); THI80 (0.745); THI22 (0.729); THI74 (0.718); PHO3 (0.717); THI2 (0.713); YBR287W (0.695); THI72 (0.69); THI13 (0.671); PET18 (0.592); NRK1 (0.568); SNO2 (0.526)

Homologues (species, bitscore): NCS1 (Arabidopsis thaliana, 122.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:566574-568370:+ gene-YLR237W_AKU4011 rna-NM_001182124.1_AKU4011 cds-NP_013338.1_AKU4011 98.1 100.0 Verified 1 1 0 False False True False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:163539-165335:- gene-YLR237W_BG1 rna-NM_001182124.1_BG1 cds-NP_013338.1_BG1 98.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:600812-602608:+ gene-YLR237W_Bruggeman rna-NM_001182124.1_Bruggeman cds-NP_013338.1_Bruggeman 98.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:599936-601732:+ gene-YLR237W_CAT1 rna-NM_001182124.1_CAT1 cds-NP_013338.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:602069-603865:+ gene-YLR237W_CBS1585 rna-NM_001182124.1_CBS1585 cds-NP_013338.1_CBS1585 98.1 100.0 Verified 1 1 0 False False True False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:586278-588074:+ gene-YLR237W_CBS436 rna-NM_001182124.1_CBS436 cds-NP_013338.1_CBS436 98.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:565044-566840:+ gene-YLR237W_CBS6412 rna-NM_001182124.1_CBS6412 cds-NP_013338.1_CBS6412 98.1 100.0 Mismatch 1 1 0 False False True False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:602364-604160:+ gene-YLR237W_CBS6413 rna-NM_001182124.1_CBS6413 cds-NP_013338.1_CBS6413 98.1 100.0 Verified 1 1 0 False False True False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:596978-598774:+ gene-YLR237W_CENPK1137D rna-NM_001182124.1_CENPK1137D cds-NP_013338.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:560111-561907:+ gene-YLR237W_EthanolRed rna-NM_001182124.1_EthanolRed cds-NP_013338.1_EthanolRed 98.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:589036-590832:+ gene-YLR237W_FaliES1 rna-NM_001182124.1_FaliES1 cds-NP_013338.1_FaliES1 98.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000136.1:68059-69855:- gene-YLR237W_JAY291 rna-NM_001182124.1_JAY291 cds-NP_013338.1_JAY291 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:601670-603466:+ gene-YLR237W_MUCL30387 rna-NM_001182124.1_MUCL30387 cds-NP_013338.1_MUCL30387 98.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:605791-607587:+ gene-YLR237W_MUCL30388 rna-NM_001182124.1_MUCL30388 cds-NP_013338.1_MUCL30388 98.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:603050-604846:+ gene-YLR237W_MUCL39482 rna-NM_001182124.1_MUCL39482 cds-NP_013338.1_MUCL39482 98.1 100.0 Verified 1 1 0 False False True False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:597812-599608:+ gene-YLR237W_MUCL42920 rna-NM_001182124.1_MUCL42920 cds-NP_013338.1_MUCL42920 98.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:612341-614137:+ gene-YLR237W_NCIM3186 rna-NM_001182124.1_NCIM3186 cds-NP_013338.1_NCIM3186 94.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:590039-591835:+ gene-YLR237W_NCYC1407 rna-NM_001182124.1_NCYC1407 cds-NP_013338.1_NCYC1407 98.1 100.0 Verified 1 1 0 False False True False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:593755-595551:+ gene-YLR237W_PE2H3 rna-NM_001182124.1_PE2H3 cds-NP_013338.1_PE2H3 98.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:593499-595295:+ gene-YLR237W_PE2H4 rna-NM_001182124.1_PE2H4 cds-NP_013338.1_PE2H4 98.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:612367-614163:+ gene-YLR237W_S288C rna-NM_001182124.1_S288C cds-NP_013338.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:68309-70105:- gene-YLR237W_SA1 rna-NM_001182124.1_SA1 cds-NP_013338.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:591536-593332:+ gene-YLR237W_ThermosaccDry rna-NM_001182124.1_ThermosaccDry cds-NP_013338.1_ThermosaccDry 98.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:602870-604666:+ gene-YLR237W_VR1 rna-NM_001182124.1_VR1 cds-NP_013338.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:115851-117648:+ gene-YLR237W_ZTW1 rna-NM_001182124.1_ZTW1 cds-NP_013338.1_ZTW1 98.6 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:577003-578799:+ gene-YLR237W_Sparadoxus rna-NM_001182124.1_Sparadoxus cds-NP_013338.1_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files