Gene name: THI6
Reference locus (S288C): YPL214C
Gene biotype: protein_coding
Description: Thiamine biosynthetic bifunctional enzyme; Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
Top 10 interactors (score): THI21 (0.999); THI20 (0.999); THI4 (0.998); THI80 (0.977); PHO3 (0.97); THI22 (0.97); THI5 (0.959); THI12 (0.93); THI11 (0.918); NST1 (0.907); THI13 (0.905); LTP1 (0.904); DIA3 (0.9); PHO5 (0.9); PHO8 (0.9); PHO12 (0.9); PHO11 (0.9); THI7 (0.825); THI73 (0.75); SNZ2 (0.747)
Homologues (species, bitscore): TH1 (Arabidopsis thaliana, 139.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:126441-128063:- | gene-YPL214C_AKU4011 | rna-NM_001184028.1_AKU4011 | cds-NP_015110.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:332212-333834:- | gene-YPL214C_BG1 | rna-NM_001184028.1_BG1 | cds-NP_015110.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:151906-153528:- | gene-YPL214C_Bruggeman | rna-NM_001184028.1_Bruggeman | cds-NP_015110.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:148514-150136:- | gene-YPL214C_CAT1 | rna-NM_001184028.1_CAT1 | cds-NP_015110.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:130627-132249:- | gene-YPL214C_CBS1585 | rna-NM_001184028.1_CBS1585 | cds-NP_015110.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:145050-146672:- | gene-YPL214C_CBS436 | rna-NM_001184028.1_CBS436 | cds-NP_015110.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:135430-137052:- | gene-YPL214C_CBS6412 | rna-NM_001184028.1_CBS6412 | cds-NP_015110.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:126804-128426:- | gene-YPL214C_CBS6413 | rna-NM_001184028.1_CBS6413 | cds-NP_015110.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:148506-150128:- | gene-YPL214C_CENPK1137D | rna-NM_001184028.1_CENPK1137D | cds-NP_015110.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:125540-127162:- | gene-YPL214C_EthanolRed | rna-NM_001184028.1_EthanolRed | cds-NP_015110.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:132746-134368:- | gene-YPL214C_FaliES1 | rna-NM_001184028.1_FaliES1 | cds-NP_015110.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000069.1:23940-25562:+ | gene-YPL214C_JAY291 | rna-NM_001184028.1_JAY291 | cds-NP_015110.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:143615-145237:- | gene-YPL214C_MUCL30387 | rna-NM_001184028.1_MUCL30387 | cds-NP_015110.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:141806-143428:- | gene-YPL214C_MUCL30388 | rna-NM_001184028.1_MUCL30388 | cds-NP_015110.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:123757-125379:- | gene-YPL214C_MUCL39482 | rna-NM_001184028.1_MUCL39482 | cds-NP_015110.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:142640-144262:- | gene-YPL214C_MUCL42920 | rna-NM_001184028.1_MUCL42920 | cds-NP_015110.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:148552-150174:- | gene-YPL214C_NCIM3186 | rna-NM_001184028.1_NCIM3186 | cds-NP_015110.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:130205-131827:- | gene-YPL214C_NCYC1407 | rna-NM_001184028.1_NCYC1407 | cds-NP_015110.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:137912-139534:- | gene-YPL214C_PE2H3 | rna-NM_001184028.1_PE2H3 | cds-NP_015110.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:137555-139177:- | gene-YPL214C_PE2H4 | rna-NM_001184028.1_PE2H4 | cds-NP_015110.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:148569-150191:- | gene-YPL214C_S288C | rna-NM_001184028.1_S288C | cds-NP_015110.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000095.1:23990-25612:+ | gene-YPL214C_SA1 | rna-NM_001184028.1_SA1 | cds-NP_015110.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:132527-134149:- | gene-YPL214C_ThermosaccDry | rna-NM_001184028.1_ThermosaccDry | cds-NP_015110.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:146593-148215:- | gene-YPL214C_VR1 | rna-NM_001184028.1_VR1 | cds-NP_015110.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:132057-133679:- | gene-YPL214C_ZTW1 | rna-NM_001184028.1_ZTW1 | cds-NP_015110.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:133636-135258:- | gene-YPL214C_Sparadoxus | rna-NM_001184028.1_Sparadoxus | cds-NP_015110.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |