THI5 (YFL058W)


Gene profile

Gene name: THI5
Reference locus (S288C): YFL058W
Gene biotype: protein_coding

Description: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family

Top 10 interactors (score): THI4 (0.992); THI20 (0.988); THI21 (0.987); THI6 (0.959); YPR172W (0.9); PDX3 (0.9); YLR456W (0.9); BUD16 (0.9); SNZ2 (0.887); THI13 (0.874); THI12 (0.874); THI80 (0.869); THI11 (0.86); SNO2 (0.837); NMT1 (0.816); SNZ3 (0.814); THI22 (0.807); BUD17 (0.8); YGR017W (0.8); SNO3 (0.782)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:8600-9708:+ gene-YFL058W_AKU4011 rna-NM_001179909.1_AKU4011 cds-NP_116597.1_AKU4011 92.1 100.0 Unannotated 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000085.1:246-1268:+ gene-YFL058W_BG1 rna-NM_001179909.1_BG1 cds-NP_116597.1_BG1 97.5 100.0 Mismatch 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:14510-15542:+ gene-YFL058W_CAT1 rna-NM_001179909.1_CAT1 cds-NP_116597.1_CAT1 57.9 80.5 Unannotated 1 1 0 False False True False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:9451-10473:+ gene-YFL058W_CBS1585 rna-NM_001179909.1_CBS1585 cds-NP_116597.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:24828-25850:+ gene-YFL058W_CBS436 rna-NM_001179909.1_CBS436 cds-NP_116597.1_CBS436 87.4 100.0 Mismatch 1 1 0 False False True False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:5489-6511:+ gene-YFL058W_CBS6412 rna-NM_001179909.1_CBS6412 cds-NP_116597.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:5614-6722:+ gene-YFL058W_CBS6413 rna-NM_001179909.1_CBS6413 cds-NP_116597.1_CBS6413 92.1 100.0 Unannotated 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:9236-10268:+ gene-YFL058W_CENPK1137D rna-NM_001179909.1_CENPK1137D cds-NP_116597.1_CENPK1137D 73.6 100.0 Unannotated 1 1 0 False False True False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:8369-9390:+ gene-YFL058W_EthanolRed rna-NM_001179909.1_EthanolRed cds-NP_116597.1_EthanolRed 73.1 99.9 Unannotated 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:9575-10597:+ gene-YFL058W_FaliES1 rna-NM_001179909.1_FaliES1 cds-NP_116597.1_FaliES1 89.8 100.0 Verified 1 1 0 False False True False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:6236-7258:+ gene-YFL058W_MUCL39482 rna-NM_001179909.1_MUCL39482 cds-NP_116597.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:12928-13950:+ gene-YFL058W_NCIM3186 rna-NM_001179909.1_NCIM3186 cds-NP_116597.1_NCIM3186 99.9 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:9292-10314:+ gene-YFL058W_NCYC1407 rna-NM_001179909.1_NCYC1407 cds-NP_116597.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:684676-685698:- gene-YFL058W_PE2H3 rna-NM_001179909.1_PE2H3 cds-NP_116597.1_PE2H3 97.7 100.0 Mismatch 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:1088523-1089545:- gene-YFL058W_PE2H4 rna-NM_001179909.1_PE2H4 cds-NP_116597.1_PE2H4 97.7 100.0 Mismatch 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:12929-13951:+ gene-YFL058W_S288C rna-NM_001179909.1_S288C cds-NP_116597.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000052.1:81491-81786:- gene-YFL058W_SA1 rna-NM_001179909.1_SA1 cds-NP_116597.1_SA1 28.7 28.9 Mismatch 1 1 0 False False True False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:712739-713182:- gene-YFL058W_VR1 rna-NM_001179909.1_VR1 cds-NP_116597.1_VR1 42.9 43.4 Mismatch 1 1 0 False False True False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:15413-16436:+ gene-YFL058W_ZTW1 rna-NM_001179909.1_ZTW1 cds-NP_116597.1_ZTW1 98.7 100.0 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:723863-724885:- gene-YFL058W_Sparadoxus rna-NM_001179909.1_Sparadoxus cds-NP_116597.1_Sparadoxus 93.3 100.0 Mismatch 1 1 1 False True False False False

Additional files