Gene name: THI4
Reference locus (S288C): YGR144W
Gene biotype: protein_coding
Description: Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents
Top 10 interactors (score): THI6 (0.998); THI5 (0.992); THI80 (0.984); THI20 (0.981); THI13 (0.97); THI11 (0.969); THI21 (0.968); THI12 (0.967); YJR142W (0.907); THI7 (0.861); PET18 (0.836); PDC2 (0.821); PPS1 (0.813); PHO3 (0.782); THI2 (0.756); THI3 (0.747); THI73 (0.722); SNO2 (0.705); SNZ2 (0.701); DET1 (0.7)
Homologues (species, bitscore): THI1 (Arabidopsis thaliana, 300.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:760096-761076:+ | gene-YGR144W_AKU4011 | rna-NM_001181273.1_AKU4011 | cds-NP_011660.1_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:38018-38998:+ | gene-YGR144W_BG1 | rna-NM_001181273.1_BG1 | cds-NP_011660.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:765566-766546:+ | gene-YGR144W_Bruggeman | rna-NM_001181273.1_Bruggeman | cds-NP_011660.1_Bruggeman | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:761523-762503:+ | gene-YGR144W_CAT1 | rna-NM_001181273.1_CAT1 | cds-NP_011660.1_CAT1 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:760830-761810:+ | gene-YGR144W_CBS1585 | rna-NM_001181273.1_CBS1585 | cds-NP_011660.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:764485-765465:+ | gene-YGR144W_CBS436 | rna-NM_001181273.1_CBS436 | cds-NP_011660.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:751850-752830:+ | gene-YGR144W_CBS6412 | rna-NM_001181273.1_CBS6412 | cds-NP_011660.1_CBS6412 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:757688-758668:+ | gene-YGR144W_CBS6413 | rna-NM_001181273.1_CBS6413 | cds-NP_011660.1_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:780132-781112:+ | gene-YGR144W_CENPK1137D | rna-NM_001181273.1_CENPK1137D | cds-NP_011660.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:746398-747378:+ | gene-YGR144W_EthanolRed | rna-NM_001181273.1_EthanolRed | cds-NP_011660.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:750486-751466:+ | gene-YGR144W_FaliES1 | rna-NM_001181273.1_FaliES1 | cds-NP_011660.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000224.1:6096-7076:- | gene-YGR144W_JAY291 | rna-NM_001181273.1_JAY291 | cds-NP_011660.1_JAY291 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:763307-764287:+ | gene-YGR144W_MUCL30387 | rna-NM_001181273.1_MUCL30387 | cds-NP_011660.1_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:762999-763979:+ | gene-YGR144W_MUCL30388 | rna-NM_001181273.1_MUCL30388 | cds-NP_011660.1_MUCL30388 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:756306-757286:+ | gene-YGR144W_MUCL39482 | rna-NM_001181273.1_MUCL39482 | cds-NP_011660.1_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:770739-771719:+ | gene-YGR144W_MUCL42920 | rna-NM_001181273.1_MUCL42920 | cds-NP_011660.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:780399-781379:+ | gene-YGR144W_NCIM3186 | rna-NM_001181273.1_NCIM3186 | cds-NP_011660.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:751506-752486:+ | gene-YGR144W_NCYC1407 | rna-NM_001181273.1_NCYC1407 | cds-NP_011660.1_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:770476-771456:+ | gene-YGR144W_PE2H3 | rna-NM_001181273.1_PE2H3 | cds-NP_011660.1_PE2H3 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:775586-776566:+ | gene-YGR144W_PE2H4 | rna-NM_001181273.1_PE2H4 | cds-NP_011660.1_PE2H4 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:780399-781379:+ | gene-YGR144W_S288C | rna-NM_001181273.1_S288C | cds-NP_011660.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:15398-16378:+ | gene-YGR144W_SA1 | rna-NM_001181273.1_SA1 | cds-NP_011660.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:771109-772089:+ | gene-YGR144W_ThermosaccDry | rna-NM_001181273.1_ThermosaccDry | cds-NP_011660.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:875135-876115:+ | gene-YGR144W_VR1 | rna-NM_001181273.1_VR1 | cds-NP_011660.1_VR1 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:72959-73939:+ | gene-YGR144W_ZTW1 | rna-NM_001181273.1_ZTW1 | cds-NP_011660.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:760360-761340:+ | gene-YGR144W_Sparadoxus | rna-NM_001181273.1_Sparadoxus | cds-NP_011660.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |