THI21 (YPL258C)


Gene profile

Gene name: THI21
Reference locus (S288C): YPL258C
Gene biotype: protein_coding

Description: Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21; Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p; In the C-terminal section; belongs to the thiaminase-2 family

Top 10 interactors (score): THI6 (0.999); THI80 (0.994); THI12 (0.988); THI5 (0.987); THI11 (0.984); THI13 (0.984); THI4 (0.968); THI20 (0.927); PHO8 (0.911); PHO3 (0.892); DIA3 (0.841); THI7 (0.769); SNZ2 (0.759); PET18 (0.729); RIB4 (0.667); PHO12 (0.65); PHO11 (0.65); LTP1 (0.65); PHO5 (0.65); SNO2 (0.61)

Homologues (species, bitscore): TH1 (Arabidopsis thaliana, 165.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:37808-39463:- gene-YPL258C_AKU4011 rna-NM_001184072.1_AKU4011 cds-NP_015065.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000185.1:1339-2994:+ gene-YPL258C_BG1 rna-NM_001184072.1_BG1 cds-NP_015065.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:55056-56711:- gene-YPL258C_Bruggeman rna-NM_001184072.1_Bruggeman cds-NP_015065.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:53000-54655:- gene-YPL258C_CAT1 rna-NM_001184072.1_CAT1 cds-NP_015065.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:41516-43171:- gene-YPL258C_CBS1585 rna-NM_001184072.1_CBS1585 cds-NP_015065.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:49900-51555:- gene-YPL258C_CBS436 rna-NM_001184072.1_CBS436 cds-NP_015065.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:46420-48075:- gene-YPL258C_CBS6412 rna-NM_001184072.1_CBS6412 cds-NP_015065.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:37668-39323:- gene-YPL258C_CBS6413 rna-NM_001184072.1_CBS6413 cds-NP_015065.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:53447-55102:- gene-YPL258C_CENPK1137D rna-NM_001184072.1_CENPK1137D cds-NP_015065.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:36856-38511:- gene-YPL258C_EthanolRed rna-NM_001184072.1_EthanolRed cds-NP_015065.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:37204-38859:- gene-YPL258C_FaliES1 rna-NM_001184072.1_FaliES1 cds-NP_015065.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000190.1:1254-2909:+ gene-YPL258C_JAY291 rna-NM_001184072.1_JAY291 cds-NP_015065.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:54313-55968:- gene-YPL258C_MUCL30387 rna-NM_001184072.1_MUCL30387 cds-NP_015065.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:52509-54164:- gene-YPL258C_MUCL30388 rna-NM_001184072.1_MUCL30388 cds-NP_015065.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:34646-36301:- gene-YPL258C_MUCL39482 rna-NM_001184072.1_MUCL39482 cds-NP_015065.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:46806-48461:- gene-YPL258C_MUCL42920 rna-NM_001184072.1_MUCL42920 cds-NP_015065.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:53481-55136:- gene-YPL258C_NCIM3186 rna-NM_001184072.1_NCIM3186 cds-NP_015065.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:41093-42748:- gene-YPL258C_NCYC1407 rna-NM_001184072.1_NCYC1407 cds-NP_015065.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:44727-46382:- gene-YPL258C_PE2H3 rna-NM_001184072.1_PE2H3 cds-NP_015065.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:44713-46368:- gene-YPL258C_PE2H4 rna-NM_001184072.1_PE2H4 cds-NP_015065.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:53498-55153:- gene-YPL258C_S288C rna-NM_001184072.1_S288C cds-NP_015065.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000104.1:1376-3031:+ gene-YPL258C_SA1 rna-NM_001184072.1_SA1 cds-NP_015065.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:37205-38860:- gene-YPL258C_ThermosaccDry rna-NM_001184072.1_ThermosaccDry cds-NP_015065.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:283590-285245:- gene-YPL258C_VR1 rna-NM_001184072.1_VR1 cds-NP_015065.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:43325-44980:- gene-YPL258C_ZTW1 rna-NM_001184072.1_ZTW1 cds-NP_015065.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:45134-46789:- gene-YPL258C_Sparadoxus rna-NM_001184072.1_Sparadoxus cds-NP_015065.1_Sparadoxus 94.7 100.0 Verified 1 1 1 False True False False False

Additional files