Gene name: THG1
Reference locus (S288C): YGR024C
Gene biotype: protein_coding
Description: tRNAHis guanylyltransferase; adds a guanosine residue to the 5' end of tRNAH is after transcription and RNase P cleavage; can also catalyze reverse (3'-5') polymerization with certain substrates in a template-dependent reaction; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes
Top 10 interactors (score): HTS1 (0.986); MES1 (0.895); CCA1 (0.875); ORC2 (0.836); MSM1 (0.796); NCL1 (0.785); LOS1 (0.767); ABD1 (0.758); TRM5 (0.728); ENP2 (0.694); MIP1 (0.686); MSN5 (0.682); SEN15 (0.66); SEN34 (0.641); GPN3 (0.627); DPB11 (0.61); APP1 (0.581); YND1 (0.562); NOP14 (0.549); UTP22 (0.545)
Homologues (species, bitscore): THG1L (Homo sapiens, 234.2); Thg1l (Mus musculus, 244.6); thg1l (Danio rerio, 224.2); thg1l (Xenopus tropicalis, 229.9); l(2)35Bc (Drosophila melanogaster, 251.5); AT2G31580 (Arabidopsis thaliana, 199.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:533758-534471:- | gene-YGR024C_AKU4011 | rna-NM_001181153.3_AKU4011 | cds-NP_011538.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:41368-42081:+ | gene-YGR024C_BG1 | rna-NM_001181153.3_BG1 | cds-NP_011538.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:535263-535976:- | gene-YGR024C_Bruggeman | rna-NM_001181153.3_Bruggeman | cds-NP_011538.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:534083-534796:- | gene-YGR024C_CAT1 | rna-NM_001181153.3_CAT1 | cds-NP_011538.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:535089-535802:- | gene-YGR024C_CBS1585 | rna-NM_001181153.3_CBS1585 | cds-NP_011538.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:529860-530573:- | gene-YGR024C_CBS436 | rna-NM_001181153.3_CBS436 | cds-NP_011538.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:527847-528560:- | gene-YGR024C_CBS6412 | rna-NM_001181153.3_CBS6412 | cds-NP_011538.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:531933-532646:- | gene-YGR024C_CBS6413 | rna-NM_001181153.3_CBS6413 | cds-NP_011538.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:531751-532437:- | gene-YGR024C_CENPK1137D | rna-NM_001181153.3_CENPK1137D | cds-NP_011538.3_CENPK1137D | 88.3 | 96.2 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:521972-522685:- | gene-YGR024C_EthanolRed | rna-NM_001181153.3_EthanolRed | cds-NP_011538.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:525460-526173:- | gene-YGR024C_FaliES1 | rna-NM_001181153.3_FaliES1 | cds-NP_011538.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:64147-64860:- | gene-YGR024C_JAY291 | rna-NM_001181153.3_JAY291 | cds-NP_011538.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:532161-532874:- | gene-YGR024C_MUCL30387 | rna-NM_001181153.3_MUCL30387 | cds-NP_011538.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:534780-535493:- | gene-YGR024C_MUCL30388 | rna-NM_001181153.3_MUCL30388 | cds-NP_011538.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:530911-531624:- | gene-YGR024C_MUCL39482 | rna-NM_001181153.3_MUCL39482 | cds-NP_011538.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:540689-541402:- | gene-YGR024C_MUCL42920 | rna-NM_001181153.3_MUCL42920 | cds-NP_011538.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:531883-532596:- | gene-YGR024C_NCIM3186 | rna-NM_001181153.3_NCIM3186 | cds-NP_011538.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:525094-525807:- | gene-YGR024C_NCYC1407 | rna-NM_001181153.3_NCYC1407 | cds-NP_011538.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:527969-528682:- | gene-YGR024C_PE2H3 | rna-NM_001181153.3_PE2H3 | cds-NP_011538.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:533076-533789:- | gene-YGR024C_PE2H4 | rna-NM_001181153.3_PE2H4 | cds-NP_011538.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:531883-532596:- | gene-YGR024C_S288C | rna-NM_001181153.3_S288C | cds-NP_011538.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:23049-23762:+ | gene-YGR024C_SA1 | rna-NM_001181153.3_SA1 | cds-NP_011538.3_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:544797-545510:- | gene-YGR024C_ThermosaccDry | rna-NM_001181153.3_ThermosaccDry | cds-NP_011538.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:635239-635952:- | gene-YGR024C_VR1 | rna-NM_001181153.3_VR1 | cds-NP_011538.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:278-991:- | gene-YGR024C_ZTW1 | rna-NM_001181153.3_ZTW1 | cds-NP_011538.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:533459-534172:- | gene-YGR024C_Sparadoxus | rna-NM_001181153.3_Sparadoxus | cds-NP_011538.3_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |