Gene name: TGS1
Reference locus (S288C): YPL157W
Gene biotype: protein_coding
Description: Trimethyl guanosine synthase, conserved nucleolar methyl transferase; converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for nucleolar assembly and splicing of meiotic pre-mRNAs; interacts with Swm2p, which may confer substrate specificity on Tgs1p
Top 10 interactors (score): SMB1 (0.981); MUD2 (0.975); CBC2 (0.973); SWM2 (0.967); NAM8 (0.942); BRR1 (0.899); MSL5 (0.897); CWC21 (0.886); SNP1 (0.876); SMD3 (0.856); MUD1 (0.849); ISY1 (0.834); SWT21 (0.821); LEA1 (0.806); GET1 (0.795); IST3 (0.787); RTC6 (0.779); NOP56 (0.752); BUD13 (0.738); SNU56 (0.733)
Homologues (species, bitscore): TGS1 (Homo sapiens, 132.5); Tgs1 (Mus musculus, 128.6); Tgs1 (Danio rerio, 147.5); tgs1 (Xenopus tropicalis, 131.3); Tgs1 (Drosophila melanogaster, 125.6); T08G11.4 (Caenorhabditis elegans, 124.4); AT1G45231 (Arabidopsis thaliana, 130.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:232470-233417:+ | gene-YPL157W_AKU4011 | rna-NM_001183971.1_AKU4011 | cds-NP_015168.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:438146-439093:+ | gene-YPL157W_BG1 | rna-NM_001183971.1_BG1 | cds-NP_015168.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:258461-259408:+ | gene-YPL157W_Bruggeman | rna-NM_001183971.1_Bruggeman | cds-NP_015168.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:255135-256082:+ | gene-YPL157W_CAT1 | rna-NM_001183971.1_CAT1 | cds-NP_015168.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:236533-237480:+ | gene-YPL157W_CBS1585 | rna-NM_001183971.1_CBS1585 | cds-NP_015168.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:251198-252145:+ | gene-YPL157W_CBS436 | rna-NM_001183971.1_CBS436 | cds-NP_015168.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:241211-242158:+ | gene-YPL157W_CBS6412 | rna-NM_001183971.1_CBS6412 | cds-NP_015168.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:233173-234120:+ | gene-YPL157W_CBS6413 | rna-NM_001183971.1_CBS6413 | cds-NP_015168.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:254698-255645:+ | gene-YPL157W_CENPK1137D | rna-NM_001183971.1_CENPK1137D | cds-NP_015168.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:231158-232105:+ | gene-YPL157W_EthanolRed | rna-NM_001183971.1_EthanolRed | cds-NP_015168.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:238750-239697:+ | gene-YPL157W_FaliES1 | rna-NM_001183971.1_FaliES1 | cds-NP_015168.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:126150-127097:- | gene-YPL157W_JAY291 | rna-NM_001183971.1_JAY291 | cds-NP_015168.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:249703-250650:+ | gene-YPL157W_MUCL30387 | rna-NM_001183971.1_MUCL30387 | cds-NP_015168.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:247720-248667:+ | gene-YPL157W_MUCL30388 | rna-NM_001183971.1_MUCL30388 | cds-NP_015168.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:229862-230809:+ | gene-YPL157W_MUCL39482 | rna-NM_001183971.1_MUCL39482 | cds-NP_015168.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:286592-287539:+ | gene-YPL157W_MUCL42920 | rna-NM_001183971.1_MUCL42920 | cds-NP_015168.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:254797-255744:+ | gene-YPL157W_NCIM3186 | rna-NM_001183971.1_NCIM3186 | cds-NP_015168.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:236325-237272:+ | gene-YPL157W_NCYC1407 | rna-NM_001183971.1_NCYC1407 | cds-NP_015168.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:243760-244707:+ | gene-YPL157W_PE2H3 | rna-NM_001183971.1_PE2H3 | cds-NP_015168.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:243403-244350:+ | gene-YPL157W_PE2H4 | rna-NM_001183971.1_PE2H4 | cds-NP_015168.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:254814-255761:+ | gene-YPL157W_S288C | rna-NM_001183971.1_S288C | cds-NP_015168.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:117925-118872:- | gene-YPL157W_SA1 | rna-NM_001183971.1_SA1 | cds-NP_015168.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:238548-239495:+ | gene-YPL157W_ThermosaccDry | rna-NM_001183971.1_ThermosaccDry | cds-NP_015168.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:253531-254478:+ | gene-YPL157W_VR1 | rna-NM_001183971.1_VR1 | cds-NP_015168.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:237877-238824:+ | gene-YPL157W_ZTW1 | rna-NM_001183971.1_ZTW1 | cds-NP_015168.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:239493-240440:+ | gene-YPL157W_Sparadoxus | rna-NM_001183971.1_Sparadoxus | cds-NP_015168.1_Sparadoxus | 88.8 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |