Gene name: TGL4
Reference locus (S288C): YKR089C
Gene biotype: protein_coding
Description: Lipase 4; Multifunctional lipase/hydrolase/phospholipase; triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A2; catalyzes acyl-CoA dependent acylation of LPA to PA; required with Tgl3p for timely bud formation; phosphorylated and activated by Cdc28p; TGL4 has a paralog, TGL5, that arose from the whole genome duplication
Top 10 interactors (score): DGA1 (0.992); LRO1 (0.991); YJU3 (0.989); TGL1 (0.985); AYR1 (0.984); TGL5 (0.984); ALE1 (0.976); TGL3 (0.976); NTE1 (0.972); DGK1 (0.967); SCT1 (0.966); GPT2 (0.959); TGL2 (0.959); PLB2 (0.955); PSD1 (0.954); OPI3 (0.95); PSD2 (0.95); SPO14 (0.945); CDS1 (0.943); PLB3 (0.943)
Homologues (species, bitscore): SDP1 (Arabidopsis thaliana, 262.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:591664-594396:- | gene-YKR089C_AKU4011 | rna-NM_001179879.1_AKU4011 | cds-NP_013015.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:49829-52561:+ | gene-YKR089C_BG1 | rna-NM_001179879.1_BG1 | cds-NP_013015.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:614242-616974:- | gene-YKR089C_Bruggeman | rna-NM_001179879.1_Bruggeman | cds-NP_013015.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:610163-612895:- | gene-YKR089C_CAT1 | rna-NM_001179879.1_CAT1 | cds-NP_013015.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:604151-606883:- | gene-YKR089C_CBS1585 | rna-NM_001179879.1_CBS1585 | cds-NP_013015.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:602536-605268:- | gene-YKR089C_CBS436 | rna-NM_001179879.1_CBS436 | cds-NP_013015.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:587439-590171:- | gene-YKR089C_CBS6412 | rna-NM_001179879.1_CBS6412 | cds-NP_013015.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:603969-606701:- | gene-YKR089C_CBS6413 | rna-NM_001179879.1_CBS6413 | cds-NP_013015.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:605288-608020:- | gene-YKR089C_CENPK1137D | rna-NM_001179879.1_CENPK1137D | cds-NP_013015.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:601475-604207:- | gene-YKR089C_EthanolRed | rna-NM_001179879.1_EthanolRed | cds-NP_013015.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:605370-608102:- | gene-YKR089C_FaliES1 | rna-NM_001179879.1_FaliES1 | cds-NP_013015.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000426.1:36831-39563:+ | gene-YKR089C_JAY291 | rna-NM_001179879.1_JAY291 | cds-NP_013015.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:613737-616469:- | gene-YKR089C_MUCL30387 | rna-NM_001179879.1_MUCL30387 | cds-NP_013015.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:608081-610813:- | gene-YKR089C_MUCL30388 | rna-NM_001179879.1_MUCL30388 | cds-NP_013015.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:602992-605724:- | gene-YKR089C_MUCL39482 | rna-NM_001179879.1_MUCL39482 | cds-NP_013015.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:609015-611747:- | gene-YKR089C_MUCL42920 | rna-NM_001179879.1_MUCL42920 | cds-NP_013015.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:605622-608354:- | gene-YKR089C_NCIM3186 | rna-NM_001179879.1_NCIM3186 | cds-NP_013015.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:603404-606136:- | gene-YKR089C_NCYC1407 | rna-NM_001179879.1_NCYC1407 | cds-NP_013015.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:628609-631341:- | gene-YKR089C_PE2H3 | rna-NM_001179879.1_PE2H3 | cds-NP_013015.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:613013-615745:- | gene-YKR089C_PE2H4 | rna-NM_001179879.1_PE2H4 | cds-NP_013015.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:605633-608365:- | gene-YKR089C_S288C | rna-NM_001179879.1_S288C | cds-NP_013015.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000029.1:73484-76216:+ | gene-YKR089C_SA1 | rna-NM_001179879.1_SA1 | cds-NP_013015.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:604617-607349:- | gene-YKR089C_ThermosaccDry | rna-NM_001179879.1_ThermosaccDry | cds-NP_013015.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:603880-606612:- | gene-YKR089C_VR1 | rna-NM_001179879.1_VR1 | cds-NP_013015.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:601598-604330:- | gene-YKR089C_ZTW1 | rna-NM_001179879.1_ZTW1 | cds-NP_013015.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:626860-629592:- | gene-YKR089C_Sparadoxus | rna-NM_001179879.1_Sparadoxus | cds-NP_013015.1_Sparadoxus | 90.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |