TGL1 (YKL140W)


Gene profile

Gene name: TGL1
Reference locus (S288C): YKL140W
Gene biotype: protein_coding

Description: Sterol esterase TGL1; Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes

Top 10 interactors (score): TGL3 (0.996); TGL5 (0.987); TGL4 (0.985); ARE2 (0.982); FAT1 (0.945); DGA1 (0.945); ARE1 (0.944); AYR1 (0.916); LRO1 (0.877); ERG7 (0.859); YJU3 (0.85); TGL2 (0.827); LDH1 (0.763); FAA4 (0.743); EHT1 (0.731); ROG1 (0.712); PET10 (0.71); YIM1 (0.708); GPT2 (0.666); FOX2 (0.665)

Homologues (species, bitscore): LIPA (Homo sapiens, 177.9); Lipa (Mus musculus, 178.3); lipf (Danio rerio, 157.9); lipa (Xenopus tropicalis, 142.9); Lip3 (Drosophila melanogaster, 147.1); lipl-1 (Caenorhabditis elegans, 144.4); At2g15230 (Arabidopsis thaliana, 123.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:167660-169306:+ gene-YKL140W_AKU4011 rna-NM_001179706.1_AKU4011 cds-NP_012782.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:144818-146464:+ gene-YKL140W_BG1 rna-NM_001179706.1_BG1 cds-NP_012782.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:185323-186969:+ gene-YKL140W_Bruggeman rna-NM_001179706.1_Bruggeman cds-NP_012782.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:180634-182280:+ gene-YKL140W_CAT1 rna-NM_001179706.1_CAT1 cds-NP_012782.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:179911-181557:+ gene-YKL140W_CBS1585 rna-NM_001179706.1_CBS1585 cds-NP_012782.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:178491-180137:+ gene-YKL140W_CBS436 rna-NM_001179706.1_CBS436 cds-NP_012782.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:164534-166180:+ gene-YKL140W_CBS6412 rna-NM_001179706.1_CBS6412 cds-NP_012782.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:180357-182003:+ gene-YKL140W_CBS6413 rna-NM_001179706.1_CBS6413 cds-NP_012782.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:180423-182069:+ gene-YKL140W_CENPK1137D rna-NM_001179706.1_CENPK1137D cds-NP_012782.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:178392-180038:+ gene-YKL140W_EthanolRed rna-NM_001179706.1_EthanolRed cds-NP_012782.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:179204-180850:+ gene-YKL140W_FaliES1 rna-NM_001179706.1_FaliES1 cds-NP_012782.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:1529-3175:+ gene-YKL140W_JAY291 rna-NM_001179706.1_JAY291 cds-NP_012782.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:187420-189066:+ gene-YKL140W_MUCL30387 rna-NM_001179706.1_MUCL30387 cds-NP_012782.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:181772-183418:+ gene-YKL140W_MUCL30388 rna-NM_001179706.1_MUCL30388 cds-NP_012782.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:179690-181336:+ gene-YKL140W_MUCL39482 rna-NM_001179706.1_MUCL39482 cds-NP_012782.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:184083-185729:+ gene-YKL140W_MUCL42920 rna-NM_001179706.1_MUCL42920 cds-NP_012782.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:180768-182414:+ gene-YKL140W_NCIM3186 rna-NM_001179706.1_NCIM3186 cds-NP_012782.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:179880-181526:+ gene-YKL140W_NCYC1407 rna-NM_001179706.1_NCYC1407 cds-NP_012782.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:186997-188643:+ gene-YKL140W_PE2H3 rna-NM_001179706.1_PE2H3 cds-NP_012782.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:183281-184927:+ gene-YKL140W_PE2H4 rna-NM_001179706.1_PE2H4 cds-NP_012782.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:180779-182425:+ gene-YKL140W_S288C rna-NM_001179706.1_S288C cds-NP_012782.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:97222-98868:+ gene-YKL140W_SA1 rna-NM_001179706.1_SA1 cds-NP_012782.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:179904-181550:+ gene-YKL140W_ThermosaccDry rna-NM_001179706.1_ThermosaccDry cds-NP_012782.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:179257-180903:+ gene-YKL140W_VR1 rna-NM_001179706.1_VR1 cds-NP_012782.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:178440-180086:+ gene-YKL140W_ZTW1 rna-NM_001179706.1_ZTW1 cds-NP_012782.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:195148-196794:+ gene-YKL140W_Sparadoxus rna-NM_001179706.1_Sparadoxus cds-NP_012782.1_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files