Gene name: TFS1
Reference locus (S288C): YLR178C
Gene biotype: protein_coding
Description: Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p); phosphatidylethanolamine-binding protein (PEBP) family member and ortholog of hPEBP1/RKIP, a natural metastasis suppressor; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): PRC1 (0.996); MSC1 (0.994); UGA1 (0.988); PRB1 (0.983); GAD1 (0.978); SOL4 (0.976); NNR1 (0.975); DCS2 (0.975); RTC3 (0.975); YJR096W (0.969); YHR138C (0.968); PGM2 (0.964); SEC4 (0.964); NQM1 (0.959); GDB1 (0.949); DDR2 (0.946); MRPL19 (0.944); RTN2 (0.943); APE1 (0.943); FPR1 (0.939)
Homologues (species, bitscore): PEBP1 (Homo sapiens, 62.8); Pbp2 (Mus musculus, 62.4); pebp1 (Danio rerio, 60.1); pebp1 (Xenopus tropicalis, 60.1); CG17919 (Drosophila melanogaster, 73.6); F40A3.3 (Caenorhabditis elegans, 70.5); E12A11 (Arabidopsis thaliana, 54.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:467291-467950:- | gene-YLR178C_AKU4011 | rna-NM_001182065.1_AKU4011 | cds-NP_013279.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:24488-25147:- | gene-YLR178C_BG1 | rna-NM_001182065.1_BG1 | cds-NP_013279.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:507542-508201:- | gene-YLR178C_Bruggeman | rna-NM_001182065.1_Bruggeman | cds-NP_013279.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:507134-507793:- | gene-YLR178C_CAT1 | rna-NM_001182065.1_CAT1 | cds-NP_013279.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:502786-503445:- | gene-YLR178C_CBS1585 | rna-NM_001182065.1_CBS1585 | cds-NP_013279.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:492924-493583:- | gene-YLR178C_CBS436 | rna-NM_001182065.1_CBS436 | cds-NP_013279.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:471343-472002:- | gene-YLR178C_CBS6412 | rna-NM_001182065.1_CBS6412 | cds-NP_013279.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:503078-503737:- | gene-YLR178C_CBS6413 | rna-NM_001182065.1_CBS6413 | cds-NP_013279.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:497815-498474:- | gene-YLR178C_CENPK1137D | rna-NM_001182065.1_CENPK1137D | cds-NP_013279.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:466811-467470:- | gene-YLR178C_EthanolRed | rna-NM_001182065.1_EthanolRed | cds-NP_013279.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:495738-496397:- | gene-YLR178C_FaliES1 | rna-NM_001182065.1_FaliES1 | cds-NP_013279.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:22644-23303:- | gene-YLR178C_JAY291 | rna-NM_001182065.1_JAY291 | cds-NP_013279.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:507563-508222:- | gene-YLR178C_MUCL30387 | rna-NM_001182065.1_MUCL30387 | cds-NP_013279.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:512495-513154:- | gene-YLR178C_MUCL30388 | rna-NM_001182065.1_MUCL30388 | cds-NP_013279.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:503767-504426:- | gene-YLR178C_MUCL39482 | rna-NM_001182065.1_MUCL39482 | cds-NP_013279.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:504267-504926:- | gene-YLR178C_MUCL42920 | rna-NM_001182065.1_MUCL42920 | cds-NP_013279.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:513136-513795:- | gene-YLR178C_NCIM3186 | rna-NM_001182065.1_NCIM3186 | cds-NP_013279.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:496193-496852:- | gene-YLR178C_NCYC1407 | rna-NM_001182065.1_NCYC1407 | cds-NP_013279.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:500432-501091:- | gene-YLR178C_PE2H3 | rna-NM_001182065.1_PE2H3 | cds-NP_013279.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:500176-500835:- | gene-YLR178C_PE2H4 | rna-NM_001182065.1_PE2H4 | cds-NP_013279.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:513162-513821:- | gene-YLR178C_S288C | rna-NM_001182065.1_S288C | cds-NP_013279.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:22701-23360:- | gene-YLR178C_SA1 | rna-NM_001182065.1_SA1 | cds-NP_013279.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:498241-498900:- | gene-YLR178C_ThermosaccDry | rna-NM_001182065.1_ThermosaccDry | cds-NP_013279.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:509545-510204:- | gene-YLR178C_VR1 | rna-NM_001182065.1_VR1 | cds-NP_013279.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:22541-23200:- | gene-YLR178C_ZTW1 | rna-NM_001182065.1_ZTW1 | cds-NP_013279.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:484289-484948:- | gene-YLR178C_Sparadoxus | rna-NM_001182065.1_Sparadoxus | cds-NP_013279.1_Sparadoxus | 89.7 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |