TFC1 (YBR123C)


Gene profile

Gene name: TFC1
Reference locus (S288C): YBR123C
Gene biotype: protein_coding

Description: Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63

Top 10 interactors (score): TFC6 (0.999); BDP1 (0.999); TFC3 (0.999); TFC7 (0.999); TFC4 (0.999); BRF1 (0.998); TFC8 (0.998); SPT15 (0.988); TAF10 (0.957); ALG9 (0.947); RPO31 (0.935); RPC53 (0.931); PZF1 (0.92); RPC82 (0.905); RPC37 (0.861); UBC6 (0.856); RET1 (0.856); RPC31 (0.825); PML39 (0.823); RPC10 (0.818)

Homologues (species, bitscore): GTF3C5 (Homo sapiens, 53.9); Gtf3c5 (Mus musculus, 52.0); gtf3c5 (Danio rerio, 60.8); l(2)37Cd (Drosophila melanogaster, 52.8); AT5G24450 (Arabidopsis thaliana, 55.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:467624-469573:- gene-YBR123C_AKU4011 rna-NM_001178471.3_AKU4011 cds-NP_009681.3_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:458164-460113:- gene-YBR123C_BG1 rna-NM_001178471.3_BG1 cds-NP_009681.3_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:469400-471349:- gene-YBR123C_Bruggeman rna-NM_001178471.3_Bruggeman cds-NP_009681.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:472568-474517:- gene-YBR123C_CAT1 rna-NM_001178471.3_CAT1 cds-NP_009681.3_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:459408-461357:- gene-YBR123C_CBS1585 rna-NM_001178471.3_CBS1585 cds-NP_009681.3_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:467479-469428:- gene-YBR123C_CBS436 rna-NM_001178471.3_CBS436 cds-NP_009681.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:557271-559220:- gene-YBR123C_CBS6412 rna-NM_001178471.3_CBS6412 cds-NP_009681.3_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:465036-466985:- gene-YBR123C_CBS6413 rna-NM_001178471.3_CBS6413 cds-NP_009681.3_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:478514-480462:- gene-YBR123C_CENPK1137D rna-NM_001178471.3_CENPK1137D cds-NP_009681.3_CENPK1137D 99.9 99.9 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:593646-595595:- gene-YBR123C_EthanolRed rna-NM_001178471.3_EthanolRed cds-NP_009681.3_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:483663-485612:- gene-YBR123C_FaliES1 rna-NM_001178471.3_FaliES1 cds-NP_009681.3_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000444.1:7070-9018:- gene-YBR123C_JAY291 rna-NM_001178471.3_JAY291 cds-NP_009681.3_JAY291 99.5 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:472308-474257:- gene-YBR123C_MUCL30387 rna-NM_001178471.3_MUCL30387 cds-NP_009681.3_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:470660-472609:- gene-YBR123C_MUCL30388 rna-NM_001178471.3_MUCL30388 cds-NP_009681.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:457801-459750:- gene-YBR123C_MUCL39482 rna-NM_001178471.3_MUCL39482 cds-NP_009681.3_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:467715-469664:- gene-YBR123C_MUCL42920 rna-NM_001178471.3_MUCL42920 cds-NP_009681.3_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:484539-486488:- gene-YBR123C_NCIM3186 rna-NM_001178471.3_NCIM3186 cds-NP_009681.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:460329-462278:- gene-YBR123C_NCYC1407 rna-NM_001178471.3_NCYC1407 cds-NP_009681.3_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:472908-474857:- gene-YBR123C_PE2H3 rna-NM_001178471.3_PE2H3 cds-NP_009681.3_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:470584-472533:- gene-YBR123C_PE2H4 rna-NM_001178471.3_PE2H4 cds-NP_009681.3_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:484742-486691:- gene-YBR123C_S288C rna-NM_001178471.3_S288C cds-NP_009681.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000032.1:5841-7790:- gene-YBR123C_SA1 rna-NM_001178471.3_SA1 cds-NP_009681.3_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:482670-484619:- gene-YBR123C_ThermosaccDry rna-NM_001178471.3_ThermosaccDry cds-NP_009681.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:464162-466111:- gene-YBR123C_VR1 rna-NM_001178471.3_VR1 cds-NP_009681.3_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:457817-459766:- gene-YBR123C_ZTW1 rna-NM_001178471.3_ZTW1 cds-NP_009681.3_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:495063-497012:- gene-YBR123C_Sparadoxus rna-NM_001178471.3_Sparadoxus cds-NP_009681.3_Sparadoxus 90.4 100.0 Verified 1 1 1 False True False False False

Additional files