TFA1 (YKL028W)


Gene profile

Gene name: TFA1
Reference locus (S288C): YKL028W
Gene biotype: protein_coding

Description: Transcription initiation factor IIE subunit alpha; TFIIE large subunit; involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening

Top 10 interactors (score): RAD3 (0.999); TFG1 (0.999); KIN28 (0.999); SSL2 (0.999); TFB5 (0.999); RPO21 (0.999); TFB2 (0.999); TFA2 (0.999); CCL1 (0.999); TFB1 (0.999); SUA7 (0.999); TFG2 (0.999); TOA1 (0.999); SSL1 (0.999); SPT15 (0.998); RPC10 (0.998); RPB9 (0.998); RPB5 (0.998); TFB3 (0.997); TOA2 (0.996)

Homologues (species, bitscore): GTF2E1 (Homo sapiens, 116.7); Gtf2e1 (Mus musculus, 115.2); gtf2e1 (Danio rerio, 108.2); gtf2e1.2 (Xenopus tropicalis, 119.4); TfIIEalpha (Drosophila melanogaster, 107.8); ZK550.4 (Caenorhabditis elegans, 73.6); AT1G03280 (Arabidopsis thaliana, 72.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:371770-373224:+ gene-YKL028W_AKU4011 rna-NM_001179594.3_AKU4011 cds-NP_012897.3_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:270871-272289:- gene-YKL028W_BG1 rna-NM_001179594.3_BG1 cds-NP_012897.3_BG1 97.1 97.9 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:393463-394920:+ gene-YKL028W_Bruggeman rna-NM_001179594.3_Bruggeman cds-NP_012897.3_Bruggeman 98.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:388402-389847:+ gene-YKL028W_CAT1 rna-NM_001179594.3_CAT1 cds-NP_012897.3_CAT1 99.2 99.7 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:384495-385943:+ gene-YKL028W_CBS1585 rna-NM_001179594.3_CBS1585 cds-NP_012897.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:383174-384601:+ gene-YKL028W_CBS436 rna-NM_001179594.3_CBS436 cds-NP_012897.3_CBS436 97.5 98.5 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:368651-370099:+ gene-YKL028W_CBS6412 rna-NM_001179594.3_CBS6412 cds-NP_012897.3_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:384350-385798:+ gene-YKL028W_CBS6413 rna-NM_001179594.3_CBS6413 cds-NP_012897.3_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:385435-386883:+ gene-YKL028W_CENPK1137D rna-NM_001179594.3_CENPK1137D cds-NP_012897.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:382266-383720:+ gene-YKL028W_EthanolRed rna-NM_001179594.3_EthanolRed cds-NP_012897.3_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:384358-385809:+ gene-YKL028W_FaliES1 rna-NM_001179594.3_FaliES1 cds-NP_012897.3_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000142.1:45426-46847:- gene-YKL028W_JAY291 rna-NM_001179594.3_JAY291 cds-NP_012897.3_JAY291 97.3 98.1 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:392539-393984:+ gene-YKL028W_MUCL30387 rna-NM_001179594.3_MUCL30387 cds-NP_012897.3_MUCL30387 99.3 99.7 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:1008432-1009880:+ gene-YKL028W_MUCL30388 rna-NM_001179594.3_MUCL30388 cds-NP_012897.3_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:383812-385260:+ gene-YKL028W_MUCL39482 rna-NM_001179594.3_MUCL39482 cds-NP_012897.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:389213-390649:+ gene-YKL028W_MUCL42920 rna-NM_001179594.3_MUCL42920 cds-NP_012897.3_MUCL42920 97.2 98.5 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:385747-387195:+ gene-YKL028W_NCIM3186 rna-NM_001179594.3_NCIM3186 cds-NP_012897.3_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:384004-385452:+ gene-YKL028W_NCYC1407 rna-NM_001179594.3_NCYC1407 cds-NP_012897.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:408534-409952:+ gene-YKL028W_PE2H3 rna-NM_001179594.3_PE2H3 cds-NP_012897.3_PE2H3 97.1 97.9 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:393257-394699:+ gene-YKL028W_PE2H4 rna-NM_001179594.3_PE2H4 cds-NP_012897.3_PE2H4 96.7 98.5 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:385758-387206:+ gene-YKL028W_S288C rna-NM_001179594.3_S288C cds-NP_012897.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:64037-65485:+ gene-YKL028W_SA1 rna-NM_001179594.3_SA1 cds-NP_012897.3_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:384454-385908:+ gene-YKL028W_ThermosaccDry rna-NM_001179594.3_ThermosaccDry cds-NP_012897.3_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:383536-384978:+ gene-YKL028W_VR1 rna-NM_001179594.3_VR1 cds-NP_012897.3_VR1 96.7 98.5 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:382485-383936:+ gene-YKL028W_ZTW1 rna-NM_001179594.3_ZTW1 cds-NP_012897.3_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:401314-402738:+ gene-YKL028W_Sparadoxus rna-NM_001179594.3_Sparadoxus cds-NP_012897.3_Sparadoxus 89.9 98.3 Verified 1 1 1 False True False False False

Additional files