TEP1 (YNL128W)


Gene profile

Gene name: TEP1
Reference locus (S288C): YNL128W
Gene biotype: protein_coding

Description: Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1; PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1

Top 10 interactors (score): CHC1 (0.99); UBP15 (0.986); VPS34 (0.976); FAB1 (0.968); INP51 (0.958); MSS4 (0.956); INP53 (0.954); INP52 (0.948); PLC1 (0.945); STT4 (0.945); SAC1 (0.94); RHB1 (0.938); PIK1 (0.934); CKA1 (0.928); CKA2 (0.928); PIS1 (0.914); CDC25 (0.91); CKB2 (0.904); LSB6 (0.903); MRE11 (0.895)

Homologues (species, bitscore): PTEN (Homo sapiens, 87.0); Pten (Mus musculus, 87.0); ptena (Danio rerio, 89.0); pten (Xenopus tropicalis, 83.6); Pten (Drosophila melanogaster, 79.0); daf-18 (Caenorhabditis elegans, 74.7); PTEN2A (Arabidopsis thaliana, 69.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:376043-377347:+ gene-YNL128W_AKU4011 rna-NM_001182966.4_AKU4011 cds-NP_014271.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:280037-281341:+ gene-YNL128W_BG1 rna-NM_001182966.4_BG1 cds-NP_014271.3_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:386138-387442:+ gene-YNL128W_Bruggeman rna-NM_001182966.4_Bruggeman cds-NP_014271.3_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:429339-430643:+ gene-YNL128W_CAT1 rna-NM_001182966.4_CAT1 cds-NP_014271.3_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:376663-377967:+ gene-YNL128W_CBS1585 rna-NM_001182966.4_CBS1585 cds-NP_014271.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:445054-446358:+ gene-YNL128W_CBS436 rna-NM_001182966.4_CBS436 cds-NP_014271.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:372116-373420:+ gene-YNL128W_CBS6412 rna-NM_001182966.4_CBS6412 cds-NP_014271.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:373081-374385:+ gene-YNL128W_CBS6413 rna-NM_001182966.4_CBS6413 cds-NP_014271.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:376209-377513:+ gene-YNL128W_CENPK1137D rna-NM_001182966.4_CENPK1137D cds-NP_014271.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:373033-374337:+ gene-YNL128W_EthanolRed rna-NM_001182966.4_EthanolRed cds-NP_014271.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:368935-370239:+ gene-YNL128W_FaliES1 rna-NM_001182966.4_FaliES1 cds-NP_014271.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000021.1:25313-26617:+ gene-YNL128W_JAY291 rna-NM_001182966.4_JAY291 cds-NP_014271.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:382154-383458:+ gene-YNL128W_MUCL30387 rna-NM_001182966.4_MUCL30387 cds-NP_014271.3_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:417267-418571:+ gene-YNL128W_MUCL30388 rna-NM_001182966.4_MUCL30388 cds-NP_014271.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:373942-375246:+ gene-YNL128W_MUCL39482 rna-NM_001182966.4_MUCL39482 cds-NP_014271.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:376932-378236:+ gene-YNL128W_MUCL42920 rna-NM_001182966.4_MUCL42920 cds-NP_014271.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:382328-383632:+ gene-YNL128W_NCIM3186 rna-NM_001182966.4_NCIM3186 cds-NP_014271.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:376074-377378:+ gene-YNL128W_NCYC1407 rna-NM_001182966.4_NCYC1407 cds-NP_014271.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:375062-376366:+ gene-YNL128W_PE2H3 rna-NM_001182966.4_PE2H3 cds-NP_014271.3_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:374450-375754:+ gene-YNL128W_PE2H4 rna-NM_001182966.4_PE2H4 cds-NP_014271.3_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:382359-383663:+ gene-YNL128W_S288C rna-NM_001182966.4_S288C cds-NP_014271.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:29851-31155:- gene-YNL128W_SA1 rna-NM_001182966.4_SA1 cds-NP_014271.3_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:369789-371093:+ gene-YNL128W_ThermosaccDry rna-NM_001182966.4_ThermosaccDry cds-NP_014271.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:388449-389753:+ gene-YNL128W_VR1 rna-NM_001182966.4_VR1 cds-NP_014271.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:279623-280927:+ gene-YNL128W_ZTW1 rna-NM_001182966.4_ZTW1 cds-NP_014271.3_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:380585-381889:+ gene-YNL128W_Sparadoxus rna-NM_001182966.4_Sparadoxus cds-NP_014271.3_Sparadoxus 89.4 100.0 Verified 1 1 1 False True False False False

Additional files