Gene name: TEL1
Reference locus (S288C): YBL088C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase TEL1; Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene; Belongs to the PI3/PI4-kinase family. ATM subfamily
Top 10 interactors (score): RAD24 (0.999); MEC1 (0.999); MRE11 (0.999); RAD53 (0.999); RAD9 (0.999); SGS1 (0.998); CHK1 (0.998); RAD50 (0.997); RTT107 (0.996); RAD17 (0.996); YKU70 (0.994); RFA1 (0.993); DUN1 (0.991); TEL2 (0.99); RAD51 (0.99); YKU80 (0.99); DNA2 (0.989); DPB11 (0.984); RAD52 (0.983); CDC5 (0.979)
Homologues (species, bitscore): ATM (Homo sapiens, 355.5); Atm (Mus musculus, 354.0); atm (Danio rerio, 328.2); atm (Xenopus tropicalis, 334.7); tefu (Drosophila melanogaster, 265.4); atm-1 (Caenorhabditis elegans, 197.2); ATM (Arabidopsis thaliana, 322.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:44564-52927:- | gene-YBL088C_AKU4011 | rna-NM_001178328.2_AKU4011 | cds-NP_009465.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:35261-43624:- | gene-YBL088C_BG1 | rna-NM_001178328.2_BG1 | cds-NP_009465.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:45191-53554:- | gene-YBL088C_Bruggeman | rna-NM_001178328.2_Bruggeman | cds-NP_009465.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:47119-55482:- | gene-YBL088C_CAT1 | rna-NM_001178328.2_CAT1 | cds-NP_009465.2_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:36646-45009:- | gene-YBL088C_CBS1585 | rna-NM_001178328.2_CBS1585 | cds-NP_009465.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:45452-53815:- | gene-YBL088C_CBS436 | rna-NM_001178328.2_CBS436 | cds-NP_009465.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:36437-44800:- | gene-YBL088C_CBS6412 | rna-NM_001178328.2_CBS6412 | cds-NP_009465.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:42724-51087:- | gene-YBL088C_CBS6413 | rna-NM_001178328.2_CBS6413 | cds-NP_009465.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:44674-53037:- | gene-YBL088C_CENPK1137D | rna-NM_001178328.2_CENPK1137D | cds-NP_009465.2_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:58817-67180:- | gene-YBL088C_EthanolRed | rna-NM_001178328.2_EthanolRed | cds-NP_009465.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:58946-67309:- | gene-YBL088C_FaliES1 | rna-NM_001178328.2_FaliES1 | cds-NP_009465.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000184.1:35984-44347:- | gene-YBL088C_JAY291 | rna-NM_001178328.2_JAY291 | cds-NP_009465.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:44332-52695:- | gene-YBL088C_MUCL30387 | rna-NM_001178328.2_MUCL30387 | cds-NP_009465.2_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:45004-53367:- | gene-YBL088C_MUCL30388 | rna-NM_001178328.2_MUCL30388 | cds-NP_009465.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:36796-45159:- | gene-YBL088C_MUCL39482 | rna-NM_001178328.2_MUCL39482 | cds-NP_009465.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:43671-52034:- | gene-YBL088C_MUCL42920 | rna-NM_001178328.2_MUCL42920 | cds-NP_009465.2_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:50816-59179:- | gene-YBL088C_NCIM3186 | rna-NM_001178328.2_NCIM3186 | cds-NP_009465.2_NCIM3186 | 96.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:38472-46835:- | gene-YBL088C_NCYC1407 | rna-NM_001178328.2_NCYC1407 | cds-NP_009465.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:44781-53144:- | gene-YBL088C_PE2H3 | rna-NM_001178328.2_PE2H3 | cds-NP_009465.2_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:42423-50786:- | gene-YBL088C_PE2H4 | rna-NM_001178328.2_PE2H4 | cds-NP_009465.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:51019-59382:- | gene-YBL088C_S288C | rna-NM_001178328.2_S288C | cds-NP_009465.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:35125-43488:- | gene-YBL088C_SA1 | rna-NM_001178328.2_SA1 | cds-NP_009465.2_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:58907-67270:- | gene-YBL088C_ThermosaccDry | rna-NM_001178328.2_ThermosaccDry | cds-NP_009465.2_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:41109-49472:- | gene-YBL088C_VR1 | rna-NM_001178328.2_VR1 | cds-NP_009465.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:36128-44491:- | gene-YBL088C_ZTW1 | rna-NM_001178328.2_ZTW1 | cds-NP_009465.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:70860-79223:- | gene-YBL088C_Sparadoxus | rna-NM_001178328.2_Sparadoxus | cds-NP_009465.2_Sparadoxus | 87.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |