Gene name: TEF2
Reference locus (S288C): YBR118W
Gene biotype: protein_coding
Description: Translational elongation factor EF-1 alpha; in the GTP-bound active form, binds to and delivers aminoacylated tRNA to the A-site of ribosomes for elongation of nascent polypeptides; associates with vacuolar Rho1p GTPase; TEF2-RFP levels increase during replicative aging; may also have a role in tRNA re-export from the nucleus; TEF2 has a paralog, TEF1, that arose from the whole genome duplication
Top 10 interactors (score): EFB1 (0.999); TEF4 (0.999); CAM1 (0.995); TEF1 (0.992); YEF3 (0.987); RPL3 (0.981); RPL5 (0.98); ASC1 (0.978); RPS2 (0.975); TIF1 (0.963); ACT1 (0.961); RPL4B (0.961); RPS5 (0.961); RPL4A (0.959); TIF2 (0.959); ZPR1 (0.957); RPS3 (0.957); TDH3 (0.953); RPP0 (0.946); TDH2 (0.939)
Homologues (species, bitscore): EEF1A1 (Homo sapiens, 771.5); Eef1a1 (Mus musculus, 772.3); eef1a1l1 (Danio rerio, 777.3); eef1a1o (Xenopus tropicalis, 770.8); F1 (Drosophila melanogaster, 750.7); eef-1A.1 (Caenorhabditis elegans, 754.2); A1 (Arabidopsis thaliana, 696.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:460059-461633:+ | gene-YBR118W_AKU4011 | rna-NM_001178466.1_AKU4011 | cds-NP_009676.1_AKU4011 | 80.8 | 96.2 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:451095-452471:+ | gene-YBR118W_BG1 | rna-NM_001178466.1_BG1 | cds-NP_009676.1_BG1 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:462081-463436:+ | gene-YBR118W_Bruggeman | rna-NM_001178466.1_Bruggeman | cds-NP_009676.1_Bruggeman | 96.9 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:550571-551581:+ | gene-YBR118W_CBS6412 | rna-NM_001178466.1_CBS6412 | cds-NP_009676.1_CBS6412 | 50.1 | 73.4 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:457720-459075:+ | gene-YBR118W_CBS6413 | rna-NM_001178466.1_CBS6413 | cds-NP_009676.1_CBS6413 | 96.8 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:471432-472808:+ | gene-YBR118W_CENPK1137D | rna-NM_001178466.1_CENPK1137D | cds-NP_009676.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:476343-477698:+ | gene-YBR118W_FaliES1 | rna-NM_001178466.1_FaliES1 | cds-NP_009676.1_FaliES1 | 96.9 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000444.1:1-1377:+ | gene-YBR118W_JAY291 | rna-NM_001178466.1_JAY291 | cds-NP_009676.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:464990-466345:+ | gene-YBR118W_MUCL30387 | rna-NM_001178466.1_MUCL30387 | cds-NP_009676.1_MUCL30387 | 96.9 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:463342-464697:+ | gene-YBR118W_MUCL30388 | rna-NM_001178466.1_MUCL30388 | cds-NP_009676.1_MUCL30388 | 96.9 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:450485-451840:+ | gene-YBR118W_MUCL39482 | rna-NM_001178466.1_MUCL39482 | cds-NP_009676.1_MUCL39482 | 96.8 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:460396-461751:+ | gene-YBR118W_MUCL42920 | rna-NM_001178466.1_MUCL42920 | cds-NP_009676.1_MUCL42920 | 96.9 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:477468-478844:+ | gene-YBR118W_NCIM3186 | rna-NM_001178466.1_NCIM3186 | cds-NP_009676.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:465839-467215:+ | gene-YBR118W_PE2H3 | rna-NM_001178466.1_PE2H3 | cds-NP_009676.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:463515-464891:+ | gene-YBR118W_PE2H4 | rna-NM_001178466.1_PE2H4 | cds-NP_009676.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:477671-479047:+ | gene-YBR118W_S288C | rna-NM_001178466.1_S288C | cds-NP_009676.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:475350-476705:+ | gene-YBR118W_ThermosaccDry | rna-NM_001178466.1_ThermosaccDry | cds-NP_009676.1_ThermosaccDry | 96.8 | 98.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:450750-452126:+ | gene-YBR118W_ZTW1 | rna-NM_001178466.1_ZTW1 | cds-NP_009676.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:487950-489326:+ | gene-YBR118W_Sparadoxus | rna-NM_001178466.1_Sparadoxus | cds-NP_009676.1_Sparadoxus | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |