TEF1 (YPR080W)


Gene profile

Gene name: TEF1
Reference locus (S288C): YPR080W
Gene biotype: protein_coding

Description: Translational elongation factor EF-1 alpha; in the GTP-bound active form, binds to and delivers aminoacylated tRNA to the A-site of ribosomes for elongation of nascent polypeptides; associates with vacuolar Rho1p GTPase; may also have a role in tRNA re-export from the nucleus; TEF1 has a paralog, TEF2, that arose from the whole genome duplication

Top 10 interactors (score): EFB1 (0.999); CAM1 (0.999); TEF4 (0.999); ACT1 (0.999); RPS2 (0.997); TDH3 (0.993); TEF2 (0.992); RPL4A (0.992); YEF3 (0.992); RPL5 (0.992); TDH2 (0.992); RPL3 (0.99); ASC1 (0.99); PGK1 (0.989); RPP0 (0.987); RPS3 (0.986); EFT1 (0.985); RPS5 (0.983); TIF2 (0.982); EFM4 (0.975)

Homologues (species, bitscore): EEF1A1 (Homo sapiens, 771.5); Eef1a1 (Mus musculus, 772.3); eef1a1l1 (Danio rerio, 777.3); eef1a1o (Xenopus tropicalis, 770.8); F1 (Drosophila melanogaster, 750.7); eef-1A.1 (Caenorhabditis elegans, 754.2); A1 (Arabidopsis thaliana, 696.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:224028-225404:- gene-YPR080W_BG1 rna-NM_001184177.1_BG1 cds-NP_015405.1_BG1 99.9 100.0 Mismatch 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:794256-795632:+ gene-YPR080W_CAT1 rna-NM_001184177.1_CAT1 cds-NP_015405.1_CAT1 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:675953-677308:+ gene-YPR080W_CBS1585 rna-NM_001184177.1_CBS1585 cds-NP_015405.1_CBS1585 96.8 98.4 Mismatch 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:690578-691954:+ gene-YPR080W_CBS436 rna-NM_001184177.1_CBS436 cds-NP_015405.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia MBVQ01000056.1:1-1163:- gene-YPR080W_CBS6412 rna-NM_001184177.1_CBS6412 cds-NP_015405.1_CBS6412 84.3 84.4 Mismatch 1 1 0 False False True False False
EthanolRed GCA_001738615.1 Bioethanol Asia MBWB01000031.1:1-1316:- gene-YPR080W_EthanolRed rna-NM_001184177.1_EthanolRed cds-NP_015405.1_EthanolRed 95.4 95.5 Mismatch 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000094.1:1-1377:+ gene-YPR080W_JAY291 rna-NM_001184177.1_JAY291 cds-NP_015405.1_JAY291 100.0 100.0 Mismatch 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:700577-701953:+ gene-YPR080W_NCIM3186 rna-NM_001184177.1_NCIM3186 cds-NP_015405.1_NCIM3186 99.9 100.0 Mismatch 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:677386-678741:+ gene-YPR080W_NCYC1407 rna-NM_001184177.1_NCYC1407 cds-NP_015405.1_NCYC1407 96.8 98.4 Mismatch 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:684037-685413:+ gene-YPR080W_PE2H3 rna-NM_001184177.1_PE2H3 cds-NP_015405.1_PE2H3 100.0 100.0 Mismatch 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:683685-685061:+ gene-YPR080W_PE2H4 rna-NM_001184177.1_PE2H4 cds-NP_015405.1_PE2H4 100.0 100.0 Mismatch 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:700594-701970:+ gene-YPR080W_S288C rna-NM_001184177.1_S288C cds-NP_015405.1_S288C 100.0 100.0 Mismatch 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000203.1:1-1377:+ gene-YPR080W_SA1 rna-NM_001184177.1_SA1 cds-NP_015405.1_SA1 100.0 100.0 Mismatch 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:694276-695652:+ gene-YPR080W_VR1 rna-NM_001184177.1_VR1 cds-NP_015405.1_VR1 99.8 100.0 Mismatch 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:677103-678479:+ gene-YPR080W_ZTW1 rna-NM_001184177.1_ZTW1 cds-NP_015405.1_ZTW1 100.0 100.0 Mismatch 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:677798-679174:+ gene-YPR080W_Sparadoxus rna-NM_001184177.1_Sparadoxus cds-NP_015405.1_Sparadoxus 98.8 100.0 Mismatch 1 1 1 False True False False False

Additional files