Gene name: TDH3
Reference locus (S288C): YGR192C
Gene biotype: protein_coding
Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bacteria; binds AU-rich RNA
Top 10 interactors (score): TDH1 (0.999); TPI1 (0.999); PGK1 (0.999); FBA1 (0.999); TDH2 (0.999); ENO1 (0.996); PGI1 (0.994); ENO2 (0.994); CDC19 (0.994); TEF1 (0.993); GPM1 (0.992); ZWF1 (0.983); ADH1 (0.981); TKL1 (0.972); ACT1 (0.971); PDC1 (0.97); TAL1 (0.966); TEF2 (0.953); TKL2 (0.946); CCW12 (0.944)
Homologues (species, bitscore): GAPDH (Homo sapiens, 455.7); Gapdh (Mus musculus, 463.8); gapdh (Danio rerio, 465.3); gapdh (Xenopus tropicalis, 450.3); Gapdh2 (Drosophila melanogaster, 447.2); gpd-1 (Caenorhabditis elegans, 452.2); GAPC2 (Arabidopsis thaliana, 479.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:848328-849326:- | gene-YGR192C_AKU4011 | rna-NM_001181321.3_AKU4011 | cds-NP_011708.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:128661-129659:- | gene-YGR192C_BG1 | rna-NM_001181321.3_BG1 | cds-NP_011708.3_BG1 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:856522-857520:- | gene-YGR192C_Bruggeman | rna-NM_001181321.3_Bruggeman | cds-NP_011708.3_Bruggeman | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:854535-855533:- | gene-YGR192C_CAT1 | rna-NM_001181321.3_CAT1 | cds-NP_011708.3_CAT1 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:851770-852768:- | gene-YGR192C_CBS1585 | rna-NM_001181321.3_CBS1585 | cds-NP_011708.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:855127-856125:- | gene-YGR192C_CBS436 | rna-NM_001181321.3_CBS436 | cds-NP_011708.3_CBS436 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:842641-843639:- | gene-YGR192C_CBS6412 | rna-NM_001181321.3_CBS6412 | cds-NP_011708.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:848699-849697:- | gene-YGR192C_CBS6413 | rna-NM_001181321.3_CBS6413 | cds-NP_011708.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:882538-883536:- | gene-YGR192C_CENPK1137D | rna-NM_001181321.3_CENPK1137D | cds-NP_011708.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:837149-838147:- | gene-YGR192C_EthanolRed | rna-NM_001181321.3_EthanolRed | cds-NP_011708.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:841540-842538:- | gene-YGR192C_FaliES1 | rna-NM_001181321.3_FaliES1 | cds-NP_011708.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000148.1:1-268:- | gene-YGR192C_JAY291 | rna-NM_001181321.3_JAY291 | cds-NP_011708.3_JAY291 | 26.8 | 26.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:854012-855010:- | gene-YGR192C_MUCL30387 | rna-NM_001181321.3_MUCL30387 | cds-NP_011708.3_MUCL30387 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:853698-854696:- | gene-YGR192C_MUCL30388 | rna-NM_001181321.3_MUCL30388 | cds-NP_011708.3_MUCL30388 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:846843-847841:- | gene-YGR192C_MUCL39482 | rna-NM_001181321.3_MUCL39482 | cds-NP_011708.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:864395-865393:- | gene-YGR192C_MUCL42920 | rna-NM_001181321.3_MUCL42920 | cds-NP_011708.3_MUCL42920 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:882812-883810:- | gene-YGR192C_NCIM3186 | rna-NM_001181321.3_NCIM3186 | cds-NP_011708.3_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:842501-843499:- | gene-YGR192C_NCYC1407 | rna-NM_001181321.3_NCYC1407 | cds-NP_011708.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:867110-868108:- | gene-YGR192C_PE2H3 | rna-NM_001181321.3_PE2H3 | cds-NP_011708.3_PE2H3 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:872220-873218:- | gene-YGR192C_PE2H4 | rna-NM_001181321.3_PE2H4 | cds-NP_011708.3_PE2H4 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:882812-883810:- | gene-YGR192C_S288C | rna-NM_001181321.3_S288C | cds-NP_011708.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000101.1:4261-5259:- | gene-YGR192C_SA1 | rna-NM_001181321.3_SA1 | cds-NP_011708.3_SA1 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:862051-863049:- | gene-YGR192C_ThermosaccDry | rna-NM_001181321.3_ThermosaccDry | cds-NP_011708.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:966542-967540:- | gene-YGR192C_VR1 | rna-NM_001181321.3_VR1 | cds-NP_011708.3_VR1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:163497-164495:- | gene-YGR192C_ZTW1 | rna-NM_001181321.3_ZTW1 | cds-NP_011708.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:854337-855335:- | gene-YGR192C_Sparadoxus | rna-NM_001181321.3_Sparadoxus | cds-NP_011708.3_Sparadoxus | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |