Gene name: TDH2
Reference locus (S288C): YJR009C
Gene biotype: protein_coding
Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2; involved in glycolysis and gluconeogenesis; tetramer that catalyzes reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides are active against a wide variety of wine-related yeasts and bateria; TDH2 has a paralog, TDH3, that arose from the whole genome duplication
Top 10 interactors (score): TPI1 (0.999); PGK1 (0.999); TDH1 (0.999); FBA1 (0.999); TDH3 (0.999); GPM1 (0.998); ENO1 (0.996); CDC19 (0.995); ENO2 (0.994); PGI1 (0.993); TEF1 (0.992); ACT1 (0.982); ZWF1 (0.977); ADH1 (0.965); TKL1 (0.961); PDC1 (0.961); TUB3 (0.939); TEF2 (0.939); TUB1 (0.938); TKL2 (0.93)
Homologues (species, bitscore): GAPDH (Homo sapiens, 451.1); Gapdh (Mus musculus, 456.4); gapdh (Danio rerio, 466.8); gapdh (Xenopus tropicalis, 444.1); Gapdh2 (Drosophila melanogaster, 446.8); gpd-3 (Caenorhabditis elegans, 451.4); GAPC1 (Arabidopsis thaliana, 478.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:436854-437852:- | gene-YJR009C_AKU4011 | rna-NM_001181666.1_AKU4011 | cds-NP_012542.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:174876-175874:+ | gene-YJR009C_BG1 | rna-NM_001181666.1_BG1 | cds-NP_012542.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:450951-451949:- | gene-YJR009C_Bruggeman | rna-NM_001181666.1_Bruggeman | cds-NP_012542.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:454891-455889:- | gene-YJR009C_CAT1 | rna-NM_001181666.1_CAT1 | cds-NP_012542.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:448441-449439:- | gene-YJR009C_CBS1585 | rna-NM_001181666.1_CBS1585 | cds-NP_012542.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:467421-468419:- | gene-YJR009C_CBS436 | rna-NM_001181666.1_CBS436 | cds-NP_012542.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:436668-437666:- | gene-YJR009C_CBS6412 | rna-NM_001181666.1_CBS6412 | cds-NP_012542.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:438897-439895:- | gene-YJR009C_CBS6413 | rna-NM_001181666.1_CBS6413 | cds-NP_012542.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:436108-437106:- | gene-YJR009C_CENPK1137D | rna-NM_001181666.1_CENPK1137D | cds-NP_012542.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:441830-442828:- | gene-YJR009C_EthanolRed | rna-NM_001181666.1_EthanolRed | cds-NP_012542.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:452971-454043:- | gene-YJR009C_FaliES1 | rna-NM_001181666.1_FaliES1 | cds-NP_012542.1_FaliES1 | 93.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000306.1:1-306:+ | gene-YJR009C_JAY291 | rna-NM_001181666.1_JAY291 | cds-NP_012542.1_JAY291 | 30.5 | 30.6 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:451278-452276:- | gene-YJR009C_MUCL30387 | rna-NM_001181666.1_MUCL30387 | cds-NP_012542.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:447799-448797:- | gene-YJR009C_MUCL30388 | rna-NM_001181666.1_MUCL30388 | cds-NP_012542.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:441775-442893:- | gene-YJR009C_MUCL39482 | rna-NM_001181666.1_MUCL39482 | cds-NP_012542.1_MUCL39482 | 89.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:447213-448211:- | gene-YJR009C_MUCL42920 | rna-NM_001181666.1_MUCL42920 | cds-NP_012542.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:453662-454660:- | gene-YJR009C_NCIM3186 | rna-NM_001181666.1_NCIM3186 | cds-NP_012542.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:439667-440753:- | gene-YJR009C_NCYC1407 | rna-NM_001181666.1_NCYC1407 | cds-NP_012542.1_NCYC1407 | 91.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:458075-459073:- | gene-YJR009C_PE2H3 | rna-NM_001181666.1_PE2H3 | cds-NP_012542.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:451769-452767:- | gene-YJR009C_PE2H4 | rna-NM_001181666.1_PE2H4 | cds-NP_012542.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:453683-454681:- | gene-YJR009C_S288C | rna-NM_001181666.1_S288C | cds-NP_012542.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:249693-250691:- | gene-YJR009C_SA1 | rna-NM_001181666.1_SA1 | cds-NP_012542.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:446630-447693:- | gene-YJR009C_ThermosaccDry | rna-NM_001181666.1_ThermosaccDry | cds-NP_012542.1_ThermosaccDry | 93.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:448994-449992:- | gene-YJR009C_VR1 | rna-NM_001181666.1_VR1 | cds-NP_012542.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:426630-427628:- | gene-YJR009C_ZTW1 | rna-NM_001181666.1_ZTW1 | cds-NP_012542.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:451470-452468:- | gene-YJR009C_Sparadoxus | rna-NM_001181666.1_Sparadoxus | cds-NP_012542.1_Sparadoxus | 97.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |