Gene name: TDH1
Reference locus (S288C): YJL052W
Gene biotype: protein_coding
Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bateria
Top 10 interactors (score): TDH2 (0.999); FBA1 (0.999); TPI1 (0.999); PGK1 (0.999); TDH3 (0.999); ENO1 (0.996); ENO2 (0.993); PGI1 (0.991); GPM1 (0.991); ZWF1 (0.983); CDC19 (0.972); ACT1 (0.97); TKL1 (0.961); TAL1 (0.94); TUB3 (0.938); TUB1 (0.938); TKL2 (0.936); PYK2 (0.923); TUB2 (0.909); ADH1 (0.907)
Homologues (species, bitscore): GAPDH (Homo sapiens, 449.5); Gapdh (Mus musculus, 458.0); gapdh (Danio rerio, 458.0); gapdh (Xenopus tropicalis, 453.8); Gapdh2 (Drosophila melanogaster, 456.1); gpd-1 (Caenorhabditis elegans, 460.7); GAPC2 (Arabidopsis thaliana, 472.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:321087-322085:+ | gene-YJL052W_AKU4011 | rna-NM_001181485.3_AKU4011 | cds-NP_012483.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:291713-292711:- | gene-YJL052W_BG1 | rna-NM_001181485.3_BG1 | cds-NP_012483.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:333668-334666:+ | gene-YJL052W_Bruggeman | rna-NM_001181485.3_Bruggeman | cds-NP_012483.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:338902-339900:+ | gene-YJL052W_CAT1 | rna-NM_001181485.3_CAT1 | cds-NP_012483.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:332740-333738:+ | gene-YJL052W_CBS1585 | rna-NM_001181485.3_CBS1585 | cds-NP_012483.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:350794-351792:+ | gene-YJL052W_CBS436 | rna-NM_001181485.3_CBS436 | cds-NP_012483.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:321845-322843:+ | gene-YJL052W_CBS6412 | rna-NM_001181485.3_CBS6412 | cds-NP_012483.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:323192-324190:+ | gene-YJL052W_CBS6413 | rna-NM_001181485.3_CBS6413 | cds-NP_012483.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:320739-321737:+ | gene-YJL052W_CENPK1137D | rna-NM_001181485.3_CENPK1137D | cds-NP_012483.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:324923-325921:+ | gene-YJL052W_EthanolRed | rna-NM_001181485.3_EthanolRed | cds-NP_012483.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:336498-337496:+ | gene-YJL052W_FaliES1 | rna-NM_001181485.3_FaliES1 | cds-NP_012483.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:134133-134601:+ | gene-YJL052W_JAY291 | rna-NM_001181485.3_JAY291 | cds-NP_012483.3_JAY291 | 46.8 | 46.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:334822-335820:+ | gene-YJL052W_MUCL30387 | rna-NM_001181485.3_MUCL30387 | cds-NP_012483.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:330861-331859:+ | gene-YJL052W_MUCL30388 | rna-NM_001181485.3_MUCL30388 | cds-NP_012483.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:325494-326492:+ | gene-YJL052W_MUCL39482 | rna-NM_001181485.3_MUCL39482 | cds-NP_012483.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:332188-333186:+ | gene-YJL052W_MUCL42920 | rna-NM_001181485.3_MUCL42920 | cds-NP_012483.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:338250-339248:+ | gene-YJL052W_NCIM3186 | rna-NM_001181485.3_NCIM3186 | cds-NP_012483.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:324190-325188:+ | gene-YJL052W_NCYC1407 | rna-NM_001181485.3_NCYC1407 | cds-NP_012483.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:336588-337586:+ | gene-YJL052W_PE2H3 | rna-NM_001181485.3_PE2H3 | cds-NP_012483.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:336233-337231:+ | gene-YJL052W_PE2H4 | rna-NM_001181485.3_PE2H4 | cds-NP_012483.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:338271-339269:+ | gene-YJL052W_S288C | rna-NM_001181485.3_S288C | cds-NP_012483.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:134150-135148:+ | gene-YJL052W_SA1 | rna-NM_001181485.3_SA1 | cds-NP_012483.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:329911-330909:+ | gene-YJL052W_ThermosaccDry | rna-NM_001181485.3_ThermosaccDry | cds-NP_012483.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:332400-333398:+ | gene-YJL052W_VR1 | rna-NM_001181485.3_VR1 | cds-NP_012483.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:311287-312285:+ | gene-YJL052W_ZTW1 | rna-NM_001181485.3_ZTW1 | cds-NP_012483.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:335278-336276:+ | gene-YJL052W_Sparadoxus | rna-NM_001181485.3_Sparadoxus | cds-NP_012483.3_Sparadoxus | 95.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |