Gene name: TDA5
Reference locus (S288C): YLR426W
Gene biotype: protein_coding
Description: Uncharacterized oxidoreductase TDA5; Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele; Belongs to the short-chain dehydrogenases/reductases (SDR) family
Top 10 interactors (score): COS7 (0.709); TMS1 (0.694); XRS2 (0.69); VPS55 (0.674); YGL242C (0.645); SNA2 (0.618); YDR132C (0.615); YDL109C (0.612); CNL1 (0.612); MPO1 (0.6); YCR101C (0.598); IRC21 (0.598); TSC10 (0.597); DSD1 (0.578); KXD1 (0.575); POF1 (0.574); YLR108C (0.571); TVP38 (0.569); YKL075C (0.566); OCA5 (0.564)
Homologues (species, bitscore): RDH10 (Homo sapiens, 69.7); Sdr16c5 (Mus musculus, 72.0); sdr16c5b (Danio rerio, 84.7); sdr16c5 (Xenopus tropicalis, 82.0); CG15629 (Drosophila melanogaster, 80.5); dhs-4 (Caenorhabditis elegans, 75.5); AT3G55290 (Arabidopsis thaliana, 69.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:925321-926372:+ | gene-YLR426W_AKU4011 | rna-NM_001182314.1_AKU4011 | cds-NP_013530.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:157810-158861:+ | gene-YLR426W_BG1 | rna-NM_001182314.1_BG1 | cds-NP_013530.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:963624-964675:+ | gene-YLR426W_Bruggeman | rna-NM_001182314.1_Bruggeman | cds-NP_013530.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:959646-960697:+ | gene-YLR426W_CAT1 | rna-NM_001182314.1_CAT1 | cds-NP_013530.1_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:960918-961969:+ | gene-YLR426W_CBS1585 | rna-NM_001182314.1_CBS1585 | cds-NP_013530.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:950259-951310:+ | gene-YLR426W_CBS436 | rna-NM_001182314.1_CBS436 | cds-NP_013530.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:996958-998009:+ | gene-YLR426W_CBS6412 | rna-NM_001182314.1_CBS6412 | cds-NP_013530.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:961700-962751:+ | gene-YLR426W_CBS6413 | rna-NM_001182314.1_CBS6413 | cds-NP_013530.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:971684-972735:+ | gene-YLR426W_CENPK1137D | rna-NM_001182314.1_CENPK1137D | cds-NP_013530.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:918348-919399:+ | gene-YLR426W_EthanolRed | rna-NM_001182314.1_EthanolRed | cds-NP_013530.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:953619-954670:+ | gene-YLR426W_FaliES1 | rna-NM_001182314.1_FaliES1 | cds-NP_013530.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000194.1:64016-65067:- | gene-YLR426W_JAY291 | rna-NM_001182314.1_JAY291 | cds-NP_013530.1_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:962485-963536:+ | gene-YLR426W_MUCL30387 | rna-NM_001182314.1_MUCL30387 | cds-NP_013530.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:969843-970894:+ | gene-YLR426W_MUCL30388 | rna-NM_001182314.1_MUCL30388 | cds-NP_013530.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:962138-963189:+ | gene-YLR426W_MUCL39482 | rna-NM_001182314.1_MUCL39482 | cds-NP_013530.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:962634-963685:+ | gene-YLR426W_MUCL42920 | rna-NM_001182314.1_MUCL42920 | cds-NP_013530.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:987036-988087:+ | gene-YLR426W_NCIM3186 | rna-NM_001182314.1_NCIM3186 | cds-NP_013530.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:971317-972368:+ | gene-YLR426W_NCYC1407 | rna-NM_001182314.1_NCYC1407 | cds-NP_013530.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:958020-959071:+ | gene-YLR426W_PE2H3 | rna-NM_001182314.1_PE2H3 | cds-NP_013530.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:957764-958815:+ | gene-YLR426W_PE2H4 | rna-NM_001182314.1_PE2H4 | cds-NP_013530.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:987062-988113:+ | gene-YLR426W_S288C | rna-NM_001182314.1_S288C | cds-NP_013530.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:71848-72899:- | gene-YLR426W_SA1 | rna-NM_001182314.1_SA1 | cds-NP_013530.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:956698-957749:+ | gene-YLR426W_ThermosaccDry | rna-NM_001182314.1_ThermosaccDry | cds-NP_013530.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:963125-964176:+ | gene-YLR426W_VR1 | rna-NM_001182314.1_VR1 | cds-NP_013530.1_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:286972-288023:+ | gene-YLR426W_ZTW1 | rna-NM_001182314.1_ZTW1 | cds-NP_013530.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:936119-937174:+ | gene-YLR426W_Sparadoxus | rna-NM_001182314.1_Sparadoxus | cds-NP_013530.1_Sparadoxus | 88.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |