Gene name: TDA4
Reference locus (S288C): YJR116W
Gene biotype: protein_coding
Description: Topoisomerase I damage affected protein 4; Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; Belongs to the TMEM56 family
Top 10 interactors (score): YPK9 (0.775); YDC1 (0.745); LAG1 (0.722); YPC1 (0.716); TRP5 (0.71); LAC1 (0.631); YHC3 (0.598); CPR3 (0.572); ROK1 (0.474); SFB3 (0.472); AIF1 (0.472); COX12 (0.459)
Homologues (species, bitscore): TMEM56 (Homo sapiens, 63.9); tmem56a (Danio rerio, 54.7); tmem56 (Xenopus tropicalis, 65.1); AT4G10360 (Arabidopsis thaliana, 60.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:612317-613156:+ | gene-YJR116W_AKU4011 | rna-NM_001181774.1_AKU4011 | cds-NP_012650.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000076.1:60418-61257:- | gene-YJR116W_BG1 | rna-NM_001181774.1_BG1 | cds-NP_012650.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:628028-628867:+ | gene-YJR116W_Bruggeman | rna-NM_001181774.1_Bruggeman | cds-NP_012650.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:631798-632637:+ | gene-YJR116W_CAT1 | rna-NM_001181774.1_CAT1 | cds-NP_012650.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:624359-625198:+ | gene-YJR116W_CBS1585 | rna-NM_001181774.1_CBS1585 | cds-NP_012650.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:643236-644075:+ | gene-YJR116W_CBS436 | rna-NM_001181774.1_CBS436 | cds-NP_012650.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:611135-611974:+ | gene-YJR116W_CBS6412 | rna-NM_001181774.1_CBS6412 | cds-NP_012650.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:613790-614629:+ | gene-YJR116W_CBS6413 | rna-NM_001181774.1_CBS6413 | cds-NP_012650.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:623184-624023:+ | gene-YJR116W_CENPK1137D | rna-NM_001181774.1_CENPK1137D | cds-NP_012650.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:616732-617571:+ | gene-YJR116W_EthanolRed | rna-NM_001181774.1_EthanolRed | cds-NP_012650.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:628195-629034:+ | gene-YJR116W_FaliES1 | rna-NM_001181774.1_FaliES1 | cds-NP_012650.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:60091-60930:- | gene-YJR116W_JAY291 | rna-NM_001181774.1_JAY291 | cds-NP_012650.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:626827-627666:+ | gene-YJR116W_MUCL30387 | rna-NM_001181774.1_MUCL30387 | cds-NP_012650.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:624547-625386:+ | gene-YJR116W_MUCL30388 | rna-NM_001181774.1_MUCL30388 | cds-NP_012650.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:617842-618681:+ | gene-YJR116W_MUCL39482 | rna-NM_001181774.1_MUCL39482 | cds-NP_012650.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:622331-623170:+ | gene-YJR116W_MUCL42920 | rna-NM_001181774.1_MUCL42920 | cds-NP_012650.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:640804-641643:+ | gene-YJR116W_NCIM3186 | rna-NM_001181774.1_NCIM3186 | cds-NP_012650.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:615392-616231:+ | gene-YJR116W_NCYC1407 | rna-NM_001181774.1_NCYC1407 | cds-NP_012650.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:633588-634427:+ | gene-YJR116W_PE2H3 | rna-NM_001181774.1_PE2H3 | cds-NP_012650.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:627277-628116:+ | gene-YJR116W_PE2H4 | rna-NM_001181774.1_PE2H4 | cds-NP_012650.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:640825-641664:+ | gene-YJR116W_S288C | rna-NM_001181774.1_S288C | cds-NP_012650.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000069.1:60466-61305:- | gene-YJR116W_SA1 | rna-NM_001181774.1_SA1 | cds-NP_012650.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:622126-622965:+ | gene-YJR116W_ThermosaccDry | rna-NM_001181774.1_ThermosaccDry | cds-NP_012650.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:624511-625350:+ | gene-YJR116W_VR1 | rna-NM_001181774.1_VR1 | cds-NP_012650.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:601482-602321:+ | gene-YJR116W_ZTW1 | rna-NM_001181774.1_ZTW1 | cds-NP_012650.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:635671-636510:+ | gene-YJR116W_Sparadoxus | rna-NM_001181774.1_Sparadoxus | cds-NP_012650.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |