TDA4 (YJR116W)


Gene profile

Gene name: TDA4
Reference locus (S288C): YJR116W
Gene biotype: protein_coding

Description: Topoisomerase I damage affected protein 4; Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; Belongs to the TMEM56 family

Top 10 interactors (score): YPK9 (0.775); YDC1 (0.745); LAG1 (0.722); YPC1 (0.716); TRP5 (0.71); LAC1 (0.631); YHC3 (0.598); CPR3 (0.572); ROK1 (0.474); SFB3 (0.472); AIF1 (0.472); COX12 (0.459)

Homologues (species, bitscore): TMEM56 (Homo sapiens, 63.9); tmem56a (Danio rerio, 54.7); tmem56 (Xenopus tropicalis, 65.1); AT4G10360 (Arabidopsis thaliana, 60.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:612317-613156:+ gene-YJR116W_AKU4011 rna-NM_001181774.1_AKU4011 cds-NP_012650.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000076.1:60418-61257:- gene-YJR116W_BG1 rna-NM_001181774.1_BG1 cds-NP_012650.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:628028-628867:+ gene-YJR116W_Bruggeman rna-NM_001181774.1_Bruggeman cds-NP_012650.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:631798-632637:+ gene-YJR116W_CAT1 rna-NM_001181774.1_CAT1 cds-NP_012650.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:624359-625198:+ gene-YJR116W_CBS1585 rna-NM_001181774.1_CBS1585 cds-NP_012650.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:643236-644075:+ gene-YJR116W_CBS436 rna-NM_001181774.1_CBS436 cds-NP_012650.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:611135-611974:+ gene-YJR116W_CBS6412 rna-NM_001181774.1_CBS6412 cds-NP_012650.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:613790-614629:+ gene-YJR116W_CBS6413 rna-NM_001181774.1_CBS6413 cds-NP_012650.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:623184-624023:+ gene-YJR116W_CENPK1137D rna-NM_001181774.1_CENPK1137D cds-NP_012650.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:616732-617571:+ gene-YJR116W_EthanolRed rna-NM_001181774.1_EthanolRed cds-NP_012650.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:628195-629034:+ gene-YJR116W_FaliES1 rna-NM_001181774.1_FaliES1 cds-NP_012650.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000054.1:60091-60930:- gene-YJR116W_JAY291 rna-NM_001181774.1_JAY291 cds-NP_012650.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:626827-627666:+ gene-YJR116W_MUCL30387 rna-NM_001181774.1_MUCL30387 cds-NP_012650.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:624547-625386:+ gene-YJR116W_MUCL30388 rna-NM_001181774.1_MUCL30388 cds-NP_012650.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:617842-618681:+ gene-YJR116W_MUCL39482 rna-NM_001181774.1_MUCL39482 cds-NP_012650.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:622331-623170:+ gene-YJR116W_MUCL42920 rna-NM_001181774.1_MUCL42920 cds-NP_012650.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:640804-641643:+ gene-YJR116W_NCIM3186 rna-NM_001181774.1_NCIM3186 cds-NP_012650.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:615392-616231:+ gene-YJR116W_NCYC1407 rna-NM_001181774.1_NCYC1407 cds-NP_012650.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:633588-634427:+ gene-YJR116W_PE2H3 rna-NM_001181774.1_PE2H3 cds-NP_012650.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:627277-628116:+ gene-YJR116W_PE2H4 rna-NM_001181774.1_PE2H4 cds-NP_012650.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:640825-641664:+ gene-YJR116W_S288C rna-NM_001181774.1_S288C cds-NP_012650.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000069.1:60466-61305:- gene-YJR116W_SA1 rna-NM_001181774.1_SA1 cds-NP_012650.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:622126-622965:+ gene-YJR116W_ThermosaccDry rna-NM_001181774.1_ThermosaccDry cds-NP_012650.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:624511-625350:+ gene-YJR116W_VR1 rna-NM_001181774.1_VR1 cds-NP_012650.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:601482-602321:+ gene-YJR116W_ZTW1 rna-NM_001181774.1_ZTW1 cds-NP_012650.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:635671-636510:+ gene-YJR116W_Sparadoxus rna-NM_001181774.1_Sparadoxus cds-NP_012650.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files