Gene name: TDA1
Reference locus (S288C): YMR291W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase TDA1; Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress
Top 10 interactors (score): TDA3 (0.765); YKR075C (0.73); CEM1 (0.7); YLL065W (0.693); SEC4 (0.653); HLR1 (0.596); SKS1 (0.586); MCP2 (0.572); ELM1 (0.571); SCY1 (0.571); YLR446W (0.568); STB2 (0.566); PAN3 (0.562); UBX7 (0.561); TOS3 (0.539); SAK1 (0.533); HXK2 (0.532); SDD4 (0.527); PKP1 (0.526); INH1 (0.525)
Homologues (species, bitscore): DCLK3 (Homo sapiens, 136.3); Dclk3 (Mus musculus, 138.7); dckl1b (Danio rerio, 129.4); dclk3 (Xenopus tropicalis, 127.9); bt (Drosophila melanogaster, 117.5); dapk-1 (Caenorhabditis elegans, 122.9); CPK24 (Arabidopsis thaliana, 113.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:891682-893442:+ | gene-YMR291W_AKU4011 | rna-NM_001182799.1_AKU4011 | cds-NP_014019.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:60261-62021:- | gene-YMR291W_BG1 | rna-NM_001182799.1_BG1 | cds-NP_014019.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:836893-838653:+ | gene-YMR291W_Bruggeman | rna-NM_001182799.1_Bruggeman | cds-NP_014019.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:840176-841936:+ | gene-YMR291W_CAT1 | rna-NM_001182799.1_CAT1 | cds-NP_014019.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:823936-825696:+ | gene-YMR291W_CBS1585 | rna-NM_001182799.1_CBS1585 | cds-NP_014019.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:846249-848009:+ | gene-YMR291W_CBS436 | rna-NM_001182799.1_CBS436 | cds-NP_014019.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:935508-937268:+ | gene-YMR291W_CBS6412 | rna-NM_001182799.1_CBS6412 | cds-NP_014019.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:823055-824815:+ | gene-YMR291W_CBS6413 | rna-NM_001182799.1_CBS6413 | cds-NP_014019.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:847176-848936:+ | gene-YMR291W_CENPK1137D | rna-NM_001182799.1_CENPK1137D | cds-NP_014019.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:884375-886135:+ | gene-YMR291W_EthanolRed | rna-NM_001182799.1_EthanolRed | cds-NP_014019.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:830402-832162:+ | gene-YMR291W_FaliES1 | rna-NM_001182799.1_FaliES1 | cds-NP_014019.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000262.1:19571-21331:- | gene-YMR291W_JAY291 | rna-NM_001182799.1_JAY291 | cds-NP_014019.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:830717-832477:+ | gene-YMR291W_MUCL30387 | rna-NM_001182799.1_MUCL30387 | cds-NP_014019.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:840115-841875:+ | gene-YMR291W_MUCL30388 | rna-NM_001182799.1_MUCL30388 | cds-NP_014019.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:825001-826761:+ | gene-YMR291W_MUCL39482 | rna-NM_001182799.1_MUCL39482 | cds-NP_014019.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:833830-835590:+ | gene-YMR291W_MUCL42920 | rna-NM_001182799.1_MUCL42920 | cds-NP_014019.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:852584-854344:+ | gene-YMR291W_NCIM3186 | rna-NM_001182799.1_NCIM3186 | cds-NP_014019.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:824655-826415:+ | gene-YMR291W_NCYC1407 | rna-NM_001182799.1_NCYC1407 | cds-NP_014019.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:840471-842231:+ | gene-YMR291W_PE2H3 | rna-NM_001182799.1_PE2H3 | cds-NP_014019.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:836445-838205:+ | gene-YMR291W_PE2H4 | rna-NM_001182799.1_PE2H4 | cds-NP_014019.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:852630-854390:+ | gene-YMR291W_S288C | rna-NM_001182799.1_S288C | cds-NP_014019.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000036.1:30427-32187:+ | gene-YMR291W_SA1 | rna-NM_001182799.1_SA1 | cds-NP_014019.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:826570-828330:+ | gene-YMR291W_ThermosaccDry | rna-NM_001182799.1_ThermosaccDry | cds-NP_014019.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:840324-842084:+ | gene-YMR291W_VR1 | rna-NM_001182799.1_VR1 | cds-NP_014019.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:241808-243568:+ | gene-YMR291W_ZTW1 | rna-NM_001182799.1_ZTW1 | cds-NP_014019.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:845226-846986:+ | gene-YMR291W_Sparadoxus | rna-NM_001182799.1_Sparadoxus | cds-NP_014019.1_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |