TCP1 (YDR212W)


Gene profile

Gene name: TCP1
Reference locus (S288C): YDR212W
Gene biotype: protein_coding

Description: Alpha subunit of chaperonin-containing T-complex; complex mediates protein folding in the cytosol; involved in actin cytoskeleton maintenance; overexpression in neurons suppresses formation of pathogenic conformations of huntingtin protein

Top 10 interactors (score): CCT8 (0.999); CCT6 (0.999); CCT4 (0.999); CCT7 (0.999); CCT5 (0.999); CCT2 (0.999); CCT3 (0.999); CDC55 (0.969); PLP2 (0.964); ACT1 (0.964); GIM5 (0.942); FAB1 (0.942); SUI2 (0.942); HSP60 (0.94); GIM3 (0.929); CAM1 (0.926); SUB2 (0.923); RPL3 (0.921); ILS1 (0.918); TEF4 (0.918)

Homologues (species, bitscore): TCP1 (Homo sapiens, 699.1); Tcp1 (Mus musculus, 686.4); tcp1 (Danio rerio, 698.0); cct7 (Xenopus tropicalis, 288.9); T-cp1 (Drosophila melanogaster, 692.2); cct-1 (Caenorhabditis elegans, 672.5); TCP-1 (Arabidopsis thaliana, 688.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:843877-845556:+ gene-YDR212W_AKU4011 rna-NM_001180520.1_AKU4011 cds-NP_010498.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:280197-281876:- gene-YDR212W_BG1 rna-NM_001180520.1_BG1 cds-NP_010498.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:876282-877961:+ gene-YDR212W_Bruggeman rna-NM_001180520.1_Bruggeman cds-NP_010498.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:863548-865227:+ gene-YDR212W_CAT1 rna-NM_001180520.1_CAT1 cds-NP_010498.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:834230-835909:+ gene-YDR212W_CBS1585 rna-NM_001180520.1_CBS1585 cds-NP_010498.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:863297-864976:+ gene-YDR212W_CBS436 rna-NM_001180520.1_CBS436 cds-NP_010498.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:831042-832721:+ gene-YDR212W_CBS6412 rna-NM_001180520.1_CBS6412 cds-NP_010498.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:861587-863266:+ gene-YDR212W_CBS6413 rna-NM_001180520.1_CBS6413 cds-NP_010498.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:886031-887710:+ gene-YDR212W_CENPK1137D rna-NM_001180520.1_CENPK1137D cds-NP_010498.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:844617-846296:+ gene-YDR212W_EthanolRed rna-NM_001180520.1_EthanolRed cds-NP_010498.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:852823-854502:+ gene-YDR212W_FaliES1 rna-NM_001180520.1_FaliES1 cds-NP_010498.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000058.1:2754-4433:+ gene-YDR212W_JAY291 rna-NM_001180520.1_JAY291 cds-NP_010498.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:861933-863612:+ gene-YDR212W_MUCL30387 rna-NM_001180520.1_MUCL30387 cds-NP_010498.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:850187-851866:+ gene-YDR212W_MUCL30388 rna-NM_001180520.1_MUCL30388 cds-NP_010498.1_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:835682-837361:+ gene-YDR212W_MUCL39482 rna-NM_001180520.1_MUCL39482 cds-NP_010498.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:774982-776661:+ gene-YDR212W_MUCL42920 rna-NM_001180520.1_MUCL42920 cds-NP_010498.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:887155-888834:+ gene-YDR212W_NCIM3186 rna-NM_001180520.1_NCIM3186 cds-NP_010498.1_NCIM3186 99.9 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:839368-841047:+ gene-YDR212W_NCYC1407 rna-NM_001180520.1_NCYC1407 cds-NP_010498.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:855564-857243:+ gene-YDR212W_PE2H3 rna-NM_001180520.1_PE2H3 cds-NP_010498.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:860845-862524:+ gene-YDR212W_PE2H4 rna-NM_001180520.1_PE2H4 cds-NP_010498.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:887232-888911:+ gene-YDR212W_S288C rna-NM_001180520.1_S288C cds-NP_010498.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:93330-95009:+ gene-YDR212W_SA1 rna-NM_001180520.1_SA1 cds-NP_010498.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:850984-852663:+ gene-YDR212W_ThermosaccDry rna-NM_001180520.1_ThermosaccDry cds-NP_010498.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:866210-867889:+ gene-YDR212W_VR1 rna-NM_001180520.1_VR1 cds-NP_010498.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:113701-115380:+ gene-YDR212W_ZTW1 rna-NM_001180520.1_ZTW1 cds-NP_010498.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:856109-857788:+ gene-YDR212W_Sparadoxus rna-NM_001180520.1_Sparadoxus cds-NP_010498.1_Sparadoxus 93.2 100.0 Verified 1 1 1 False True False False False

Additional files