Gene name: TCD2
Reference locus (S288C): YKL027W
Gene biotype: protein_coding
Description: tRNA threonylcarbamoyladenosine dehydratase; required for the ct6A tRNA base modification, where an adenosine at position 37 is modified to form a cyclized active ester with an oxazolone ring; localized to the mitochondrial outer membrane; TCD2 has a paralog, TCD1, that arose from the whole genome duplication
Top 10 interactors (score): URM1 (0.712); UBP16 (0.697); YIL001W (0.696); ROY1 (0.671); AIM11 (0.65); SLM3 (0.641); NCS6 (0.624); WSS1 (0.604); IRC25 (0.572); PTH2 (0.569); CUZ1 (0.568); ADD66 (0.564); ELP3 (0.553); SCM4 (0.552); SAF1 (0.55); PBA1 (0.521); POC4 (0.499); PTH1 (0.497); YOR012W (0.483); YGR111W (0.482)
Homologues (species, bitscore): UBA3 (Homo sapiens, 58.2); Uba3 (Mus musculus, 58.5); uba5 (Danio rerio, 57.8); uba5 (Xenopus tropicalis, 60.5); CG13090 (Drosophila melanogaster, 65.1); T03F1.1 (Caenorhabditis elegans, 59.7); AT5G37530 (Arabidopsis thaliana, 260.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:373580-374923:+ | gene-YKL027W_AKU4011 | rna-NM_001179593.1_AKU4011 | cds-NP_012898.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:269170-270513:- | gene-YKL027W_BG1 | rna-NM_001179593.1_BG1 | cds-NP_012898.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:395276-396619:+ | gene-YKL027W_Bruggeman | rna-NM_001179593.1_Bruggeman | cds-NP_012898.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:390205-391548:+ | gene-YKL027W_CAT1 | rna-NM_001179593.1_CAT1 | cds-NP_012898.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:386299-387642:+ | gene-YKL027W_CBS1585 | rna-NM_001179593.1_CBS1585 | cds-NP_012898.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:384964-386307:+ | gene-YKL027W_CBS436 | rna-NM_001179593.1_CBS436 | cds-NP_012898.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:370455-371798:+ | gene-YKL027W_CBS6412 | rna-NM_001179593.1_CBS6412 | cds-NP_012898.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:386154-387497:+ | gene-YKL027W_CBS6413 | rna-NM_001179593.1_CBS6413 | cds-NP_012898.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:387239-388582:+ | gene-YKL027W_CENPK1137D | rna-NM_001179593.1_CENPK1137D | cds-NP_012898.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:384076-385419:+ | gene-YKL027W_EthanolRed | rna-NM_001179593.1_EthanolRed | cds-NP_012898.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:386166-387509:+ | gene-YKL027W_FaliES1 | rna-NM_001179593.1_FaliES1 | cds-NP_012898.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000142.1:43727-45070:- | gene-YKL027W_JAY291 | rna-NM_001179593.1_JAY291 | cds-NP_012898.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:394341-395684:+ | gene-YKL027W_MUCL30387 | rna-NM_001179593.1_MUCL30387 | cds-NP_012898.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:390199-391542:+ | gene-YKL027W_MUCL30388 | rna-NM_001179593.1_MUCL30388 | cds-NP_012898.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:385616-386959:+ | gene-YKL027W_MUCL39482 | rna-NM_001179593.1_MUCL39482 | cds-NP_012898.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:391257-392600:+ | gene-YKL027W_MUCL42920 | rna-NM_001179593.1_MUCL42920 | cds-NP_012898.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:387551-388894:+ | gene-YKL027W_NCIM3186 | rna-NM_001179593.1_NCIM3186 | cds-NP_012898.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:385808-387151:+ | gene-YKL027W_NCYC1407 | rna-NM_001179593.1_NCYC1407 | cds-NP_012898.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:410310-411653:+ | gene-YKL027W_PE2H3 | rna-NM_001179593.1_PE2H3 | cds-NP_012898.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:395056-396399:+ | gene-YKL027W_PE2H4 | rna-NM_001179593.1_PE2H4 | cds-NP_012898.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:387562-388905:+ | gene-YKL027W_S288C | rna-NM_001179593.1_S288C | cds-NP_012898.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:65841-67184:+ | gene-YKL027W_SA1 | rna-NM_001179593.1_SA1 | cds-NP_012898.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:386265-387608:+ | gene-YKL027W_ThermosaccDry | rna-NM_001179593.1_ThermosaccDry | cds-NP_012898.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:385335-386678:+ | gene-YKL027W_VR1 | rna-NM_001179593.1_VR1 | cds-NP_012898.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:384293-385636:+ | gene-YKL027W_ZTW1 | rna-NM_001179593.1_ZTW1 | cds-NP_012898.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:403102-404445:+ | gene-YKL027W_Sparadoxus | rna-NM_001179593.1_Sparadoxus | cds-NP_012898.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |