Gene name: TCD1
Reference locus (S288C): YHR003C
Gene biotype: protein_coding
Description: tRNA threonylcarbamoyladenosine dehydratase; required for the ct6A tRNA base modification, where an adenosine at position 37 is modified to form a cyclized active ester with an oxazolone ring; localized to the mitochondrial outer membrane; TCD1 has a paralog, TCD2, that arose from the whole genome duplication
Top 10 interactors (score): ELP3 (0.803); URM1 (0.757); DEG1 (0.746); LIA1 (0.746); ELP6 (0.639); PET8 (0.62); PUS1 (0.601); SUA5 (0.597); MCM5 (0.526); UBA4 (0.481); TOM40 (0.466); HUB1 (0.452); NCS6 (0.429); IKI3 (0.424); UIP4 (0.4); NCL1 (0.4)
Homologues (species, bitscore): moc-3 (Caenorhabditis elegans, 50.1); AT5G37530 (Arabidopsis thaliana, 206.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:98641-99930:- | gene-YHR003C_AKU4011 | rna-NM_001179133.1_AKU4011 | cds-NP_011866.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:18357-19646:- | gene-YHR003C_BG1 | rna-NM_001179133.1_BG1 | cds-NP_011866.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:105499-106788:- | gene-YHR003C_Bruggeman | rna-NM_001179133.1_Bruggeman | cds-NP_011866.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:99483-100772:- | gene-YHR003C_CAT1 | rna-NM_001179133.1_CAT1 | cds-NP_011866.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:99228-100517:- | gene-YHR003C_CBS1585 | rna-NM_001179133.1_CBS1585 | cds-NP_011866.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:91726-93015:- | gene-YHR003C_CBS436 | rna-NM_001179133.1_CBS436 | cds-NP_011866.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:98827-100116:- | gene-YHR003C_CBS6412 | rna-NM_001179133.1_CBS6412 | cds-NP_011866.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:98553-99842:- | gene-YHR003C_CBS6413 | rna-NM_001179133.1_CBS6413 | cds-NP_011866.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:103186-104475:- | gene-YHR003C_CENPK1137D | rna-NM_001179133.1_CENPK1137D | cds-NP_011866.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:98637-99926:- | gene-YHR003C_EthanolRed | rna-NM_001179133.1_EthanolRed | cds-NP_011866.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:99166-100455:- | gene-YHR003C_FaliES1 | rna-NM_001179133.1_FaliES1 | cds-NP_011866.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000064.1:21505-22794:+ | gene-YHR003C_JAY291 | rna-NM_001179133.1_JAY291 | cds-NP_011866.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:102239-103528:- | gene-YHR003C_MUCL30387 | rna-NM_001179133.1_MUCL30387 | cds-NP_011866.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:103450-104739:- | gene-YHR003C_MUCL30388 | rna-NM_001179133.1_MUCL30388 | cds-NP_011866.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:98254-99543:- | gene-YHR003C_MUCL39482 | rna-NM_001179133.1_MUCL39482 | cds-NP_011866.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:102159-103448:- | gene-YHR003C_MUCL42920 | rna-NM_001179133.1_MUCL42920 | cds-NP_011866.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:109910-111199:- | gene-YHR003C_NCIM3186 | rna-NM_001179133.1_NCIM3186 | cds-NP_011866.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:97670-98959:- | gene-YHR003C_NCYC1407 | rna-NM_001179133.1_NCYC1407 | cds-NP_011866.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:99876-101165:- | gene-YHR003C_PE2H3 | rna-NM_001179133.1_PE2H3 | cds-NP_011866.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:107317-108606:- | gene-YHR003C_PE2H4 | rna-NM_001179133.1_PE2H4 | cds-NP_011866.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:110028-111317:- | gene-YHR003C_S288C | rna-NM_001179133.1_S288C | cds-NP_011866.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000075.1:35225-36514:+ | gene-YHR003C_SA1 | rna-NM_001179133.1_SA1 | cds-NP_011866.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:100256-101545:- | gene-YHR003C_ThermosaccDry | rna-NM_001179133.1_ThermosaccDry | cds-NP_011866.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:105803-107092:- | gene-YHR003C_VR1 | rna-NM_001179133.1_VR1 | cds-NP_011866.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:91421-92710:- | gene-YHR003C_ZTW1 | rna-NM_001179133.1_ZTW1 | cds-NP_011866.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:98028-99317:- | gene-YHR003C_Sparadoxus | rna-NM_001179133.1_Sparadoxus | cds-NP_011866.1_Sparadoxus | 90.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |