TBF1 (YPL128C)


Gene profile

Gene name: TBF1
Reference locus (S288C): YPL128C
Gene biotype: protein_coding

Description: Protein TBF1; Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation

Top 10 interactors (score): VID22 (0.988); ENV11 (0.961); RAP1 (0.928); IFH1 (0.917); ABF1 (0.907); YMR090W (0.87); REB1 (0.868); CDC13 (0.851); STN1 (0.835); RIF2 (0.832); MCM1 (0.822); YBL109W (0.788); HMO1 (0.787); YDR544C (0.784); YJR162C (0.78); YMR326C (0.78); YRF1-8 (0.78); YOL166W-A (0.78); YCR108C (0.78); YKL225W (0.78)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:284186-285874:- gene-YPL128C_AKU4011 rna-NM_001183942.1_AKU4011 cds-NP_015197.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:489873-491561:- gene-YPL128C_BG1 rna-NM_001183942.1_BG1 cds-NP_015197.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:310185-311873:- gene-YPL128C_Bruggeman rna-NM_001183942.1_Bruggeman cds-NP_015197.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:306856-308544:- gene-YPL128C_CAT1 rna-NM_001183942.1_CAT1 cds-NP_015197.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:288259-289947:- gene-YPL128C_CBS1585 rna-NM_001183942.1_CBS1585 cds-NP_015197.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:302923-304611:- gene-YPL128C_CBS436 rna-NM_001183942.1_CBS436 cds-NP_015197.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:292928-294616:- gene-YPL128C_CBS6412 rna-NM_001183942.1_CBS6412 cds-NP_015197.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:284895-286583:- gene-YPL128C_CBS6413 rna-NM_001183942.1_CBS6413 cds-NP_015197.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:306435-308123:- gene-YPL128C_CENPK1137D rna-NM_001183942.1_CENPK1137D cds-NP_015197.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:282874-284562:- gene-YPL128C_EthanolRed rna-NM_001183942.1_EthanolRed cds-NP_015197.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:290466-292154:- gene-YPL128C_FaliES1 rna-NM_001183942.1_FaliES1 cds-NP_015197.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:73694-75382:+ gene-YPL128C_JAY291 rna-NM_001183942.1_JAY291 cds-NP_015197.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:301429-303117:- gene-YPL128C_MUCL30387 rna-NM_001183942.1_MUCL30387 cds-NP_015197.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:299438-301126:- gene-YPL128C_MUCL30388 rna-NM_001183942.1_MUCL30388 cds-NP_015197.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:281588-283276:- gene-YPL128C_MUCL39482 rna-NM_001183942.1_MUCL39482 cds-NP_015197.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:338826-340514:- gene-YPL128C_MUCL42920 rna-NM_001183942.1_MUCL42920 cds-NP_015197.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:306516-308204:- gene-YPL128C_NCIM3186 rna-NM_001183942.1_NCIM3186 cds-NP_015197.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:288041-289729:- gene-YPL128C_NCYC1407 rna-NM_001183942.1_NCYC1407 cds-NP_015197.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:295499-297187:- gene-YPL128C_PE2H3 rna-NM_001183942.1_PE2H3 cds-NP_015197.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:295122-296810:- gene-YPL128C_PE2H4 rna-NM_001183942.1_PE2H4 cds-NP_015197.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:306533-308221:- gene-YPL128C_S288C rna-NM_001183942.1_S288C cds-NP_015197.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:65459-67147:+ gene-YPL128C_SA1 rna-NM_001183942.1_SA1 cds-NP_015197.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:290264-291952:- gene-YPL128C_ThermosaccDry rna-NM_001183942.1_ThermosaccDry cds-NP_015197.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:305242-306930:- gene-YPL128C_VR1 rna-NM_001183942.1_VR1 cds-NP_015197.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:289589-291277:- gene-YPL128C_ZTW1 rna-NM_001183942.1_ZTW1 cds-NP_015197.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:291306-292994:- gene-YPL128C_Sparadoxus rna-NM_001183942.1_Sparadoxus cds-NP_015197.1_Sparadoxus 91.5 99.8 Verified 1 1 1 False True False False False

Additional files