Gene name: TAZ1
Reference locus (S288C): YPR140W
Gene biotype: protein_coding
Description: Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant
Top 10 interactors (score): CRD1 (0.994); ALE1 (0.983); CLD1 (0.971); LRO1 (0.943); PAH1 (0.935); TGL4 (0.934); LPP1 (0.917); DPP1 (0.915); CST26 (0.908); SLC1 (0.902); MIC19 (0.863); YDR018C (0.863); TAM41 (0.858); PGS1 (0.827); GEP4 (0.825); PUF3 (0.765); DDL1 (0.748); LOA1 (0.746); TIM10 (0.737); PSD1 (0.716)
Homologues (species, bitscore): TAZ (Homo sapiens, 81.6); Taz (Mus musculus, 85.5); taz (Danio rerio, 85.9); taz (Xenopus tropicalis, 84.7); Taz (Drosophila melanogaster, 95.1); acl-3 (Caenorhabditis elegans, 110.2); AT3G05510 (Arabidopsis thaliana, 92.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:780157-781311:+ | gene-YPR140W_AKU4011 | rna-NM_001184237.1_AKU4011 | cds-NP_015466.1_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:116056-117210:- | gene-YPR140W_BG1 | rna-NM_001184237.1_BG1 | cds-NP_015466.1_BG1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:860806-861951:+ | gene-YPR140W_Bruggeman | rna-NM_001184237.1_Bruggeman | cds-NP_015466.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:902722-903876:+ | gene-YPR140W_CAT1 | rna-NM_001184237.1_CAT1 | cds-NP_015466.1_CAT1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:784413-785567:+ | gene-YPR140W_CBS1585 | rna-NM_001184237.1_CBS1585 | cds-NP_015466.1_CBS1585 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:798886-800031:+ | gene-YPR140W_CBS436 | rna-NM_001184237.1_CBS436 | cds-NP_015466.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:787137-788291:+ | gene-YPR140W_CBS6412 | rna-NM_001184237.1_CBS6412 | cds-NP_015466.1_CBS6412 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:781859-783013:+ | gene-YPR140W_CBS6413 | rna-NM_001184237.1_CBS6413 | cds-NP_015466.1_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:814389-815534:+ | gene-YPR140W_CENPK1137D | rna-NM_001184237.1_CENPK1137D | cds-NP_015466.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1102323-1103477:+ | gene-YPR140W_EthanolRed | rna-NM_001184237.1_EthanolRed | cds-NP_015466.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:781870-783024:+ | gene-YPR140W_FaliES1 | rna-NM_001184237.1_FaliES1 | cds-NP_015466.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000036.1:39145-40299:+ | gene-YPR140W_JAY291 | rna-NM_001184237.1_JAY291 | cds-NP_015466.1_JAY291 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:800997-802142:+ | gene-YPR140W_MUCL30387 | rna-NM_001184237.1_MUCL30387 | cds-NP_015466.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:800962-802107:+ | gene-YPR140W_MUCL30388 | rna-NM_001184237.1_MUCL30388 | cds-NP_015466.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:776921-778075:+ | gene-YPR140W_MUCL39482 | rna-NM_001184237.1_MUCL39482 | cds-NP_015466.1_MUCL39482 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:840717-841862:+ | gene-YPR140W_MUCL42920 | rna-NM_001184237.1_MUCL42920 | cds-NP_015466.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:814374-815519:+ | gene-YPR140W_NCIM3186 | rna-NM_001184237.1_NCIM3186 | cds-NP_015466.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:785514-786668:+ | gene-YPR140W_NCYC1407 | rna-NM_001184237.1_NCYC1407 | cds-NP_015466.1_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:792234-793388:+ | gene-YPR140W_PE2H3 | rna-NM_001184237.1_PE2H3 | cds-NP_015466.1_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:791882-793036:+ | gene-YPR140W_PE2H4 | rna-NM_001184237.1_PE2H4 | cds-NP_015466.1_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:814391-815536:+ | gene-YPR140W_S288C | rna-NM_001184237.1_S288C | cds-NP_015466.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000028.1:106268-107413:+ | gene-YPR140W_SA1 | rna-NM_001184237.1_SA1 | cds-NP_015466.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:781315-782469:+ | gene-YPR140W_ThermosaccDry | rna-NM_001184237.1_ThermosaccDry | cds-NP_015466.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:803136-804290:+ | gene-YPR140W_VR1 | rna-NM_001184237.1_VR1 | cds-NP_015466.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:785068-786213:+ | gene-YPR140W_ZTW1 | rna-NM_001184237.1_ZTW1 | cds-NP_015466.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:787176-788324:+ | gene-YPR140W_Sparadoxus | rna-NM_001184237.1_Sparadoxus | cds-NP_015466.1_Sparadoxus | 90.9 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |