Gene name: TAH18
Reference locus (S288C): YPR048W
Gene biotype: protein_coding
Description: NADPH-dependent diflavin oxidoreductase 1; Conserved NAPDH-dependent diflavin reductase; component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; transfers electrons from NADPH to the Fe-S cluster of Dre2p; plays a pro-death role under oxidative stress; Tah18p-dependent nitric oxide synthesis confers high-temperature stress tolerance; possible target for development of antifungal drugs; In the N-terminal section; belongs to the flavodoxin family
Top 10 interactors (score): DRE2 (0.999); NBP35 (0.999); CFD1 (0.995); NAR1 (0.992); MET18 (0.992); ATM1 (0.954); YAE1 (0.93); YAH1 (0.921); CIA2 (0.906); RLI1 (0.897); NFS1 (0.888); ISD11 (0.881); GRX3 (0.876); IBA57 (0.863); CIA1 (0.848); NFU1 (0.839); LIP5 (0.839); JAC1 (0.831); POL3 (0.81); GRX5 (0.795)
Homologues (species, bitscore): NDOR1 (Homo sapiens, 284.6); Ndor1 (Mus musculus, 270.8); ndor1 (Danio rerio, 301.6); NDOR1 (Xenopus tropicalis, 249.6); CG13667 (Drosophila melanogaster, 268.9); fre-1 (Caenorhabditis elegans, 248.1); AT3G02280 (Arabidopsis thaliana, 247.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:630847-632718:+ | gene-YPR048W_AKU4011 | rna-NM_001184145.1_AKU4011 | cds-NP_015373.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:264961-266832:- | gene-YPR048W_BG1 | rna-NM_001184145.1_BG1 | cds-NP_015373.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:708516-710387:+ | gene-YPR048W_Bruggeman | rna-NM_001184145.1_Bruggeman | cds-NP_015373.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:751970-753841:+ | gene-YPR048W_CAT1 | rna-NM_001184145.1_CAT1 | cds-NP_015373.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:634533-636404:+ | gene-YPR048W_CBS1585 | rna-NM_001184145.1_CBS1585 | cds-NP_015373.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:648912-650783:+ | gene-YPR048W_CBS436 | rna-NM_001184145.1_CBS436 | cds-NP_015373.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:638281-640152:+ | gene-YPR048W_CBS6412 | rna-NM_001184145.1_CBS6412 | cds-NP_015373.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:631482-633353:+ | gene-YPR048W_CBS6413 | rna-NM_001184145.1_CBS6413 | cds-NP_015373.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:659147-661018:+ | gene-YPR048W_CENPK1137D | rna-NM_001184145.1_CENPK1137D | cds-NP_015373.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:958038-959909:+ | gene-YPR048W_EthanolRed | rna-NM_001184145.1_EthanolRed | cds-NP_015373.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:636675-638546:+ | gene-YPR048W_FaliES1 | rna-NM_001184145.1_FaliES1 | cds-NP_015373.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:8633-10504:+ | gene-YPR048W_JAY291 | rna-NM_001184145.1_JAY291 | cds-NP_015373.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:649777-651648:+ | gene-YPR048W_MUCL30387 | rna-NM_001184145.1_MUCL30387 | cds-NP_015373.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:648481-650352:+ | gene-YPR048W_MUCL30388 | rna-NM_001184145.1_MUCL30388 | cds-NP_015373.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:627790-629661:+ | gene-YPR048W_MUCL39482 | rna-NM_001184145.1_MUCL39482 | cds-NP_015373.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:690618-692489:+ | gene-YPR048W_MUCL42920 | rna-NM_001184145.1_MUCL42920 | cds-NP_015373.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:659165-661036:+ | gene-YPR048W_NCIM3186 | rna-NM_001184145.1_NCIM3186 | cds-NP_015373.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:635720-637591:+ | gene-YPR048W_NCYC1407 | rna-NM_001184145.1_NCYC1407 | cds-NP_015373.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:641936-643807:+ | gene-YPR048W_PE2H3 | rna-NM_001184145.1_PE2H3 | cds-NP_015373.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:641584-643455:+ | gene-YPR048W_PE2H4 | rna-NM_001184145.1_PE2H4 | cds-NP_015373.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:659182-661053:+ | gene-YPR048W_S288C | rna-NM_001184145.1_S288C | cds-NP_015373.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:39638-41509:- | gene-YPR048W_SA1 | rna-NM_001184145.1_SA1 | cds-NP_015373.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:636450-638321:+ | gene-YPR048W_ThermosaccDry | rna-NM_001184145.1_ThermosaccDry | cds-NP_015373.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:652609-654480:+ | gene-YPR048W_VR1 | rna-NM_001184145.1_VR1 | cds-NP_015373.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:635681-637552:+ | gene-YPR048W_ZTW1 | rna-NM_001184145.1_ZTW1 | cds-NP_015373.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:636455-638326:+ | gene-YPR048W_Sparadoxus | rna-NM_001184145.1_Sparadoxus | cds-NP_015373.1_Sparadoxus | 89.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |