Gene name: TAF12
Reference locus (S288C): YDR145W
Gene biotype: protein_coding
Description: Subunit (61/68 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A; overexpression of the human ortholog, TAF12, an oncogene involved in the formation of choroid plexus carcinomas, results in dosage chromosomal instability (dCIN) in a human cell line similar to the dCIN observed in yeast overexpressors
Top 10 interactors (score): TAF13 (0.999); TAF10 (0.999); TAF1 (0.999); SPT7 (0.999); HFI1 (0.999); NGG1 (0.999); ADA2 (0.999); TAF7 (0.999); SPT20 (0.999); SPT15 (0.999); TRA1 (0.999); SGF73 (0.999); GCN5 (0.999); TAF8 (0.999); UBP8 (0.999); TAF2 (0.999); TAF3 (0.999); SPT3 (0.999); TAF9 (0.999); SGF29 (0.999)
Homologues (species, bitscore): TAF12 (Homo sapiens, 107.8); Taf12 (Mus musculus, 106.7); taf12 (Danio rerio, 108.6); taf12 (Xenopus tropicalis, 111.3); Taf12 (Drosophila melanogaster, 91.3); taf-12 (Caenorhabditis elegans, 59.3); TAF12 (Arabidopsis thaliana, 115.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:717673-719310:+ | gene-YDR145W_AKU4011 | rna-NM_001180452.1_AKU4011 | cds-NP_010429.1_AKU4011 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:405559-407160:- | gene-YDR145W_BG1 | rna-NM_001180452.1_BG1 | cds-NP_010429.1_BG1 | 98.0 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:749729-751378:+ | gene-YDR145W_Bruggeman | rna-NM_001180452.1_Bruggeman | cds-NP_010429.1_Bruggeman | 97.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:737701-739353:+ | gene-YDR145W_CAT1 | rna-NM_001180452.1_CAT1 | cds-NP_010429.1_CAT1 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:708711-710342:+ | gene-YDR145W_CBS1585 | rna-NM_001180452.1_CBS1585 | cds-NP_010429.1_CBS1585 | 98.3 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:734620-736221:+ | gene-YDR145W_CBS436 | rna-NM_001180452.1_CBS436 | cds-NP_010429.1_CBS436 | 98.0 | 98.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:705063-706682:+ | gene-YDR145W_CBS6412 | rna-NM_001180452.1_CBS6412 | cds-NP_010429.1_CBS6412 | 99.1 | 99.6 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:734038-735678:+ | gene-YDR145W_CBS6413 | rna-NM_001180452.1_CBS6413 | cds-NP_010429.1_CBS6413 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:739175-740809:+ | gene-YDR145W_CENPK1137D | rna-NM_001180452.1_CENPK1137D | cds-NP_010429.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:719436-721067:+ | gene-YDR145W_EthanolRed | rna-NM_001180452.1_EthanolRed | cds-NP_010429.1_EthanolRed | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:726230-727861:+ | gene-YDR145W_FaliES1 | rna-NM_001180452.1_FaliES1 | cds-NP_010429.1_FaliES1 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:78370-79995:+ | gene-YDR145W_JAY291 | rna-NM_001180452.1_JAY291 | cds-NP_010429.1_JAY291 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:735653-737302:+ | gene-YDR145W_MUCL30387 | rna-NM_001180452.1_MUCL30387 | cds-NP_010429.1_MUCL30387 | 97.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:724672-726321:+ | gene-YDR145W_MUCL30388 | rna-NM_001180452.1_MUCL30388 | cds-NP_010429.1_MUCL30388 | 97.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:710053-711681:+ | gene-YDR145W_MUCL39482 | rna-NM_001180452.1_MUCL39482 | cds-NP_010429.1_MUCL39482 | 98.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:648010-649665:+ | gene-YDR145W_MUCL42920 | rna-NM_001180452.1_MUCL42920 | cds-NP_010429.1_MUCL42920 | 97.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:746661-748280:+ | gene-YDR145W_NCIM3186 | rna-NM_001180452.1_NCIM3186 | cds-NP_010429.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:709455-711086:+ | gene-YDR145W_NCYC1407 | rna-NM_001180452.1_NCYC1407 | cds-NP_010429.1_NCYC1407 | 98.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:728793-730433:+ | gene-YDR145W_PE2H3 | rna-NM_001180452.1_PE2H3 | cds-NP_010429.1_PE2H3 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:728098-729738:+ | gene-YDR145W_PE2H4 | rna-NM_001180452.1_PE2H4 | cds-NP_010429.1_PE2H4 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:746738-748357:+ | gene-YDR145W_S288C | rna-NM_001180452.1_S288C | cds-NP_010429.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:95409-97049:+ | gene-YDR145W_SA1 | rna-NM_001180452.1_SA1 | cds-NP_010429.1_SA1 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:725752-727383:+ | gene-YDR145W_ThermosaccDry | rna-NM_001180452.1_ThermosaccDry | cds-NP_010429.1_ThermosaccDry | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:739119-740969:+ | gene-YDR145W_VR1 | rna-NM_001180452.1_VR1 | cds-NP_010429.1_VR1 | 86.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:723333-725000:+ | gene-YDR145W_ZTW1 | rna-NM_001180452.1_ZTW1 | cds-NP_010429.1_ZTW1 | 96.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:727873-729582:+ | gene-YDR145W_Sparadoxus | rna-NM_001180452.1_Sparadoxus | cds-NP_010429.1_Sparadoxus | 83.3 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |