Gene name: SYM1
Reference locus (S288C): YLR251W
Gene biotype: protein_coding
Description: Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17; human homolog MPV17 is implicated in hepatocerebral mtDNA depletion syndromes (MDDS), and complements yeast null mutant
Top 10 interactors (score): YLR252W (0.975); STF2 (0.955); PEX11 (0.924); HFD1 (0.923); TFS1 (0.922); RTC3 (0.922); SOL4 (0.921); YKL091C (0.91); MSP1 (0.906); PXA2 (0.906); PXA1 (0.906); MSC1 (0.905); DCS2 (0.904); FIS1 (0.904); PEX12 (0.901); PEX13 (0.9); PEX14 (0.9); GAD1 (0.898); PGM2 (0.884); GLC3 (0.864)
Homologues (species, bitscore): MPV17 (Homo sapiens, 86.7); Mpv17 (Mus musculus, 90.5); mpv17 (Danio rerio, 94.0); pxmp2 (Xenopus tropicalis, 84.0); CG14777 (Drosophila melanogaster, 74.7); T18D3.9 (Caenorhabditis elegans, 78.2); AT5G19750 (Arabidopsis thaliana, 84.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:595675-596268:+ | gene-YLR251W_AKU4011 | rna-NM_001182138.1_AKU4011 | cds-NP_013352.1_AKU4011 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:135629-136222:- | gene-YLR251W_BG1 | rna-NM_001182138.1_BG1 | cds-NP_013352.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:629909-630502:+ | gene-YLR251W_Bruggeman | rna-NM_001182138.1_Bruggeman | cds-NP_013352.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:629038-629631:+ | gene-YLR251W_CAT1 | rna-NM_001182138.1_CAT1 | cds-NP_013352.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:631170-631763:+ | gene-YLR251W_CBS1585 | rna-NM_001182138.1_CBS1585 | cds-NP_013352.1_CBS1585 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:615375-615968:+ | gene-YLR251W_CBS436 | rna-NM_001182138.1_CBS436 | cds-NP_013352.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:594145-594738:+ | gene-YLR251W_CBS6412 | rna-NM_001182138.1_CBS6412 | cds-NP_013352.1_CBS6412 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:631465-632058:+ | gene-YLR251W_CBS6413 | rna-NM_001182138.1_CBS6413 | cds-NP_013352.1_CBS6413 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:626105-626698:+ | gene-YLR251W_CENPK1137D | rna-NM_001182138.1_CENPK1137D | cds-NP_013352.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:589788-590381:+ | gene-YLR251W_EthanolRed | rna-NM_001182138.1_EthanolRed | cds-NP_013352.1_EthanolRed | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:618625-619218:+ | gene-YLR251W_FaliES1 | rna-NM_001182138.1_FaliES1 | cds-NP_013352.1_FaliES1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:40153-40746:- | gene-YLR251W_JAY291 | rna-NM_001182138.1_JAY291 | cds-NP_013352.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:630767-631360:+ | gene-YLR251W_MUCL30387 | rna-NM_001182138.1_MUCL30387 | cds-NP_013352.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:634893-635486:+ | gene-YLR251W_MUCL30388 | rna-NM_001182138.1_MUCL30388 | cds-NP_013352.1_MUCL30388 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:632151-632744:+ | gene-YLR251W_MUCL39482 | rna-NM_001182138.1_MUCL39482 | cds-NP_013352.1_MUCL39482 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:626909-627502:+ | gene-YLR251W_MUCL42920 | rna-NM_001182138.1_MUCL42920 | cds-NP_013352.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:641438-642031:+ | gene-YLR251W_NCIM3186 | rna-NM_001182138.1_NCIM3186 | cds-NP_013352.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:619137-619730:+ | gene-YLR251W_NCYC1407 | rna-NM_001182138.1_NCYC1407 | cds-NP_013352.1_NCYC1407 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:622863-623456:+ | gene-YLR251W_PE2H3 | rna-NM_001182138.1_PE2H3 | cds-NP_013352.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:622607-623200:+ | gene-YLR251W_PE2H4 | rna-NM_001182138.1_PE2H4 | cds-NP_013352.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:641464-642057:+ | gene-YLR251W_S288C | rna-NM_001182138.1_S288C | cds-NP_013352.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:40407-41000:- | gene-YLR251W_SA1 | rna-NM_001182138.1_SA1 | cds-NP_013352.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:620634-621227:+ | gene-YLR251W_ThermosaccDry | rna-NM_001182138.1_ThermosaccDry | cds-NP_013352.1_ThermosaccDry | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:631980-632573:+ | gene-YLR251W_VR1 | rna-NM_001182138.1_VR1 | cds-NP_013352.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:144949-145542:+ | gene-YLR251W_ZTW1 | rna-NM_001182138.1_ZTW1 | cds-NP_013352.1_ZTW1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:606753-607346:+ | gene-YLR251W_Sparadoxus | rna-NM_001182138.1_Sparadoxus | cds-NP_013352.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |