Gene name: SYH1
Reference locus (S288C): YPL105C
Gene biotype: protein_coding
Description: SMY2 homolog 2; Protein of unknown function that influences nuclear pore distribution; co-purifies with ribosomes; contains a GYF domain, which bind proline-rich sequences; deletion extends chronological lifespan; SYH1 has a paralog, SMY2, that arose from the whole genome duplication
Top 10 interactors (score): DHH1 (0.845); MOT2 (0.824); TIF34 (0.793); MUD2 (0.792); MSL5 (0.777); CDC33 (0.771); YLR177W (0.757); THP3 (0.709); HEL2 (0.692); TIF35 (0.687); YEL043W (0.619); NNF2 (0.617); CLF1 (0.616); NUP2 (0.61); YPT6 (0.608); LIN1 (0.602); YHR086W-A (0.57); CDC39 (0.57); PRP39 (0.555); PRP40 (0.535)
Homologues (species, bitscore): GIGYF2 (Homo sapiens, 74.7); Gigyf2 (Mus musculus, 78.2); gigfy2 (Danio rerio, 67.4); gigyf1 (Xenopus tropicalis, 50.8); CG11148 (Drosophila melanogaster, 51.6); AT1G76720 (Arabidopsis thaliana, 55.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:330502-333051:- | gene-YPL105C_AKU4011 | rna-NM_001183919.1_AKU4011 | cds-NP_015220.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:536259-538808:- | gene-YPL105C_BG1 | rna-NM_001183919.1_BG1 | cds-NP_015220.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:356507-359056:- | gene-YPL105C_Bruggeman | rna-NM_001183919.1_Bruggeman | cds-NP_015220.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:353175-355724:- | gene-YPL105C_CAT1 | rna-NM_001183919.1_CAT1 | cds-NP_015220.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:334575-337124:- | gene-YPL105C_CBS1585 | rna-NM_001183919.1_CBS1585 | cds-NP_015220.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:349250-351799:- | gene-YPL105C_CBS436 | rna-NM_001183919.1_CBS436 | cds-NP_015220.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:339244-341793:- | gene-YPL105C_CBS6412 | rna-NM_001183919.1_CBS6412 | cds-NP_015220.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:331211-333760:- | gene-YPL105C_CBS6413 | rna-NM_001183919.1_CBS6413 | cds-NP_015220.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:352811-355360:- | gene-YPL105C_CENPK1137D | rna-NM_001183919.1_CENPK1137D | cds-NP_015220.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:329194-331743:- | gene-YPL105C_EthanolRed | rna-NM_001183919.1_EthanolRed | cds-NP_015220.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:336786-339335:- | gene-YPL105C_FaliES1 | rna-NM_001183919.1_FaliES1 | cds-NP_015220.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:26481-29030:+ | gene-YPL105C_JAY291 | rna-NM_001183919.1_JAY291 | cds-NP_015220.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:347747-350296:- | gene-YPL105C_MUCL30387 | rna-NM_001183919.1_MUCL30387 | cds-NP_015220.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:346566-349115:- | gene-YPL105C_MUCL30388 | rna-NM_001183919.1_MUCL30388 | cds-NP_015220.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:327904-330453:- | gene-YPL105C_MUCL39482 | rna-NM_001183919.1_MUCL39482 | cds-NP_015220.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:385592-388141:- | gene-YPL105C_MUCL42920 | rna-NM_001183919.1_MUCL42920 | cds-NP_015220.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:352846-355395:- | gene-YPL105C_NCIM3186 | rna-NM_001183919.1_NCIM3186 | cds-NP_015220.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:334357-336906:- | gene-YPL105C_NCYC1407 | rna-NM_001183919.1_NCYC1407 | cds-NP_015220.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:341851-344400:- | gene-YPL105C_PE2H3 | rna-NM_001183919.1_PE2H3 | cds-NP_015220.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:341474-344023:- | gene-YPL105C_PE2H4 | rna-NM_001183919.1_PE2H4 | cds-NP_015220.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:352863-355412:- | gene-YPL105C_S288C | rna-NM_001183919.1_S288C | cds-NP_015220.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:18267-20816:+ | gene-YPL105C_SA1 | rna-NM_001183919.1_SA1 | cds-NP_015220.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:336584-339133:- | gene-YPL105C_ThermosaccDry | rna-NM_001183919.1_ThermosaccDry | cds-NP_015220.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:351563-354112:- | gene-YPL105C_VR1 | rna-NM_001183919.1_VR1 | cds-NP_015220.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:335907-338456:- | gene-YPL105C_ZTW1 | rna-NM_001183919.1_ZTW1 | cds-NP_015220.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:337607-340136:- | gene-YPL105C_Sparadoxus | rna-NM_001183919.1_Sparadoxus | cds-NP_015220.1_Sparadoxus | 84.9 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |