Gene name: SYF1
Reference locus (S288C): YDR416W
Gene biotype: protein_coding
Description: Pre-mRNA-splicing factor SYF1; Member of the NineTeen Complex (NTC); that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; relocalizes to the cytosol in response to hypoxia; homologs in human and C. elegans
Top 10 interactors (score): BRR2 (0.999); PRP19 (0.999); PRP43 (0.999); RSE1 (0.999); CWC2 (0.999); SNU114 (0.999); CUS1 (0.999); PRP8 (0.999); PRP45 (0.999); ECM2 (0.999); PRP22 (0.999); ISY1 (0.999); PRP21 (0.999); BUD31 (0.999); PRP2 (0.999); CWC22 (0.999); PRP46 (0.999); PRP16 (0.999); SNT309 (0.999); CLF1 (0.999)
Homologues (species, bitscore): XAB2 (Homo sapiens, 227.6); Xab2 (Mus musculus, 227.6); xab2 (Danio rerio, 252.7); xab2 (Xenopus tropicalis, 177.2); fand (Drosophila melanogaster, 216.9); C50F2.3 (Caenorhabditis elegans, 209.1); AT5G28740 (Arabidopsis thaliana, 202.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1238566-1241145:+ | gene-YDR416W_AKU4011 | rna-NM_001180724.1_AKU4011 | cds-NP_010704.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:117071-119650:+ | gene-YDR416W_BG1 | rna-NM_001180724.1_BG1 | cds-NP_010704.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1269466-1272045:+ | gene-YDR416W_Bruggeman | rna-NM_001180724.1_Bruggeman | cds-NP_010704.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1248026-1250605:+ | gene-YDR416W_CAT1 | rna-NM_001180724.1_CAT1 | cds-NP_010704.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1233486-1236065:+ | gene-YDR416W_CBS1585 | rna-NM_001180724.1_CBS1585 | cds-NP_010704.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1252364-1254943:+ | gene-YDR416W_CBS436 | rna-NM_001180724.1_CBS436 | cds-NP_010704.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1229540-1232119:+ | gene-YDR416W_CBS6412 | rna-NM_001180724.1_CBS6412 | cds-NP_010704.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1251395-1253974:+ | gene-YDR416W_CBS6413 | rna-NM_001180724.1_CBS6413 | cds-NP_010704.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1297091-1299670:+ | gene-YDR416W_CENPK1137D | rna-NM_001180724.1_CENPK1137D | cds-NP_010704.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1242954-1245533:+ | gene-YDR416W_EthanolRed | rna-NM_001180724.1_EthanolRed | cds-NP_010704.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1246261-1248840:+ | gene-YDR416W_FaliES1 | rna-NM_001180724.1_FaliES1 | cds-NP_010704.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000181.1:6651-9230:- | gene-YDR416W_JAY291 | rna-NM_001180724.1_JAY291 | cds-NP_010704.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1253028-1255607:+ | gene-YDR416W_MUCL30387 | rna-NM_001180724.1_MUCL30387 | cds-NP_010704.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1235134-1237713:+ | gene-YDR416W_MUCL30388 | rna-NM_001180724.1_MUCL30388 | cds-NP_010704.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1224814-1227393:+ | gene-YDR416W_MUCL39482 | rna-NM_001180724.1_MUCL39482 | cds-NP_010704.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1167264-1169843:+ | gene-YDR416W_MUCL42920 | rna-NM_001180724.1_MUCL42920 | cds-NP_010704.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1298355-1300934:+ | gene-YDR416W_NCIM3186 | rna-NM_001180724.1_NCIM3186 | cds-NP_010704.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1238786-1241365:+ | gene-YDR416W_NCYC1407 | rna-NM_001180724.1_NCYC1407 | cds-NP_010704.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1248940-1251519:+ | gene-YDR416W_PE2H3 | rna-NM_001180724.1_PE2H3 | cds-NP_010704.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1254508-1257087:+ | gene-YDR416W_PE2H4 | rna-NM_001180724.1_PE2H4 | cds-NP_010704.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1298432-1301011:+ | gene-YDR416W_S288C | rna-NM_001180724.1_S288C | cds-NP_010704.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000071.1:6776-9355:- | gene-YDR416W_SA1 | rna-NM_001180724.1_SA1 | cds-NP_010704.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1250523-1253102:+ | gene-YDR416W_ThermosaccDry | rna-NM_001180724.1_ThermosaccDry | cds-NP_010704.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1265744-1268323:+ | gene-YDR416W_VR1 | rna-NM_001180724.1_VR1 | cds-NP_010704.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:293335-295914:+ | gene-YDR416W_ZTW1 | rna-NM_001180724.1_ZTW1 | cds-NP_010704.1_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1245747-1248319:+ | gene-YDR416W_Sparadoxus | rna-NM_001180724.1_Sparadoxus | cds-NP_010704.1_Sparadoxus | 86.7 | 99.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |