Gene name: SWT1
Reference locus (S288C): YOR166C
Gene biotype: protein_coding
Description: Transcriptional protein SWT1; RNA endoribonuclease involved in perinuclear mRNP quality control; involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain; Belongs to the SWT1 family
Top 10 interactors (score): YRA1 (0.84); DIS3 (0.829); THO2 (0.793); SUB2 (0.77); RAT1 (0.762); ESL2 (0.76); NMD4 (0.747); PML1 (0.716); PML39 (0.71); MTR4 (0.707); ESL1 (0.693); NOB1 (0.69); ESC1 (0.681); TRM1 (0.68); PNS1 (0.677); HRB1 (0.673); NUP60 (0.672); FCF1 (0.664); HPR1 (0.654); XRN1 (0.633)
Homologues (species, bitscore): SWT1 (Homo sapiens, 63.2); Swt1 (Mus musculus, 55.5); swt1 (Danio rerio, 70.5); SMG6 (Xenopus tropicalis, 54.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:644764-646140:- | gene-YOR166C_AKU4011 | rna-NM_001183585.3_AKU4011 | cds-NP_014809.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:46519-47895:- | gene-YOR166C_BG1 | rna-NM_001183585.3_BG1 | cds-NP_014809.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:628838-630214:- | gene-YOR166C_Bruggeman | rna-NM_001183585.3_Bruggeman | cds-NP_014809.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:628857-630233:- | gene-YOR166C_CAT1 | rna-NM_001183585.3_CAT1 | cds-NP_014809.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:627259-628635:- | gene-YOR166C_CBS1585 | rna-NM_001183585.3_CBS1585 | cds-NP_014809.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:625554-626930:- | gene-YOR166C_CBS436 | rna-NM_001183585.3_CBS436 | cds-NP_014809.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:624871-626247:- | gene-YOR166C_CBS6412 | rna-NM_001183585.3_CBS6412 | cds-NP_014809.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:633552-634928:- | gene-YOR166C_CBS6413 | rna-NM_001183585.3_CBS6413 | cds-NP_014809.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:646885-648261:- | gene-YOR166C_CENPK1137D | rna-NM_001183585.3_CENPK1137D | cds-NP_014809.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:620968-622344:- | gene-YOR166C_EthanolRed | rna-NM_001183585.3_EthanolRed | cds-NP_014809.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:625821-627197:- | gene-YOR166C_FaliES1 | rna-NM_001183585.3_FaliES1 | cds-NP_014809.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:16344-17720:+ | gene-YOR166C_JAY291 | rna-NM_001183585.3_JAY291 | cds-NP_014809.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:633645-635021:- | gene-YOR166C_MUCL30387 | rna-NM_001183585.3_MUCL30387 | cds-NP_014809.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:640408-641784:- | gene-YOR166C_MUCL30388 | rna-NM_001183585.3_MUCL30388 | cds-NP_014809.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:635100-636476:- | gene-YOR166C_MUCL39482 | rna-NM_001183585.3_MUCL39482 | cds-NP_014809.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:644522-645898:- | gene-YOR166C_MUCL42920 | rna-NM_001183585.3_MUCL42920 | cds-NP_014809.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:647015-648391:- | gene-YOR166C_NCIM3186 | rna-NM_001183585.3_NCIM3186 | cds-NP_014809.3_NCIM3186 | 89.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:635186-636562:- | gene-YOR166C_NCYC1407 | rna-NM_001183585.3_NCYC1407 | cds-NP_014809.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:633699-635075:- | gene-YOR166C_PE2H3 | rna-NM_001183585.3_PE2H3 | cds-NP_014809.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:644076-645452:- | gene-YOR166C_PE2H4 | rna-NM_001183585.3_PE2H4 | cds-NP_014809.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:647126-648502:- | gene-YOR166C_S288C | rna-NM_001183585.3_S288C | cds-NP_014809.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:63684-65060:- | gene-YOR166C_SA1 | rna-NM_001183585.3_SA1 | cds-NP_014809.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:625004-626380:- | gene-YOR166C_ThermosaccDry | rna-NM_001183585.3_ThermosaccDry | cds-NP_014809.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:688701-690077:- | gene-YOR166C_VR1 | rna-NM_001183585.3_VR1 | cds-NP_014809.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:358452-359828:- | gene-YOR166C_ZTW1 | rna-NM_001183585.3_ZTW1 | cds-NP_014809.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:630076-631446:- | gene-YOR166C_Sparadoxus | rna-NM_001183585.3_Sparadoxus | cds-NP_014809.3_Sparadoxus | 82.9 | 98.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |