Gene name: SWR1
Reference locus (S288C): YDR334W
Gene biotype: protein_coding
Description: Helicase SWR1; Swi2/Snf2-related ATPase; structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; relocalizes to the cytosol in response to hypoxia; chronological aging factor that mediates lifespan extension by dietary restriction; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily
Top 10 interactors (score): RVB1 (0.999); SWC5 (0.999); ACT1 (0.999); RVB2 (0.999); SWC4 (0.999); VPS72 (0.999); ARP4 (0.999); VPS71 (0.999); HTZ1 (0.999); ARP6 (0.999); BDF1 (0.998); TRA1 (0.998); YAF9 (0.998); SWC7 (0.995); EAF7 (0.994); INO80 (0.993); SET1 (0.991); SWC3 (0.991); EAF3 (0.99); EPL1 (0.988)
Homologues (species, bitscore): SRCAP (Homo sapiens, 494.6); Srcap (Mus musculus, 504.6); srcap (Danio rerio, 654.4); INO80 (Xenopus tropicalis, 471.9); dom (Drosophila melanogaster, 754.6); ssl-1 (Caenorhabditis elegans, 708.4); PIE1 (Arabidopsis thaliana, 754.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1081968-1086512:+ | gene-YDR334W_AKU4011 | rna-NM_001180642.1_AKU4011 | cds-NP_010621.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:45044-49588:- | gene-YDR334W_BG1 | rna-NM_001180642.1_BG1 | cds-NP_010621.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1109516-1114060:+ | gene-YDR334W_Bruggeman | rna-NM_001180642.1_Bruggeman | cds-NP_010621.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1096262-1100806:+ | gene-YDR334W_CAT1 | rna-NM_001180642.1_CAT1 | cds-NP_010621.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1076412-1080956:+ | gene-YDR334W_CBS1585 | rna-NM_001180642.1_CBS1585 | cds-NP_010621.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1094799-1099343:+ | gene-YDR334W_CBS436 | rna-NM_001180642.1_CBS436 | cds-NP_010621.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1073100-1077644:+ | gene-YDR334W_CBS6412 | rna-NM_001180642.1_CBS6412 | cds-NP_010621.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1094331-1098875:+ | gene-YDR334W_CBS6413 | rna-NM_001180642.1_CBS6413 | cds-NP_010621.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1134567-1139127:+ | gene-YDR334W_CENPK1137D | rna-NM_001180642.1_CENPK1137D | cds-NP_010621.1_CENPK1137D | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:257508-262052:+ | gene-YDR334W_EthanolRed | rna-NM_001180642.1_EthanolRed | cds-NP_010621.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1088723-1093267:+ | gene-YDR334W_FaliES1 | rna-NM_001180642.1_FaliES1 | cds-NP_010621.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:41240-45784:+ | gene-YDR334W_JAY291 | rna-NM_001180642.1_JAY291 | cds-NP_010621.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1094760-1099304:+ | gene-YDR334W_MUCL30387 | rna-NM_001180642.1_MUCL30387 | cds-NP_010621.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1083717-1088261:+ | gene-YDR334W_MUCL30388 | rna-NM_001180642.1_MUCL30388 | cds-NP_010621.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1068219-1072763:+ | gene-YDR334W_MUCL39482 | rna-NM_001180642.1_MUCL39482 | cds-NP_010621.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1015293-1019837:+ | gene-YDR334W_MUCL42920 | rna-NM_001180642.1_MUCL42920 | cds-NP_010621.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1135855-1140399:+ | gene-YDR334W_NCIM3186 | rna-NM_001180642.1_NCIM3186 | cds-NP_010621.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1081510-1086054:+ | gene-YDR334W_NCYC1407 | rna-NM_001180642.1_NCYC1407 | cds-NP_010621.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1092520-1097064:+ | gene-YDR334W_PE2H3 | rna-NM_001180642.1_PE2H3 | cds-NP_010621.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1098105-1102649:+ | gene-YDR334W_PE2H4 | rna-NM_001180642.1_PE2H4 | cds-NP_010621.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1135932-1140476:+ | gene-YDR334W_S288C | rna-NM_001180642.1_S288C | cds-NP_010621.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:106742-111286:+ | gene-YDR334W_SA1 | rna-NM_001180642.1_SA1 | cds-NP_010621.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1092996-1097540:+ | gene-YDR334W_ThermosaccDry | rna-NM_001180642.1_ThermosaccDry | cds-NP_010621.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1108912-1113456:+ | gene-YDR334W_VR1 | rna-NM_001180642.1_VR1 | cds-NP_010621.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:137107-141651:+ | gene-YDR334W_ZTW1 | rna-NM_001180642.1_ZTW1 | cds-NP_010621.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1088408-1092949:+ | gene-YDR334W_Sparadoxus | rna-NM_001180642.1_Sparadoxus | cds-NP_010621.1_Sparadoxus | 88.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |