Gene name: SWI5
Reference locus (S288C): YDR146C
Gene biotype: protein_coding
Description: Transcriptional factor SWI5; Transcription factor that recruits Mediator and Swi/Snf complexes; activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; required for expression of the HO gene controlling mating type switching; localization to nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase; SWI5 has a paralog, ACE2, that arose from the whole genome duplication
Top 10 interactors (score): CDC28 (0.993); CLB2 (0.993); FKH2 (0.987); CTS1 (0.98); CDC20 (0.977); CDC14 (0.977); FKH1 (0.974); MCM1 (0.972); CLB1 (0.97); CBK1 (0.969); NDD1 (0.955); SWI4 (0.948); MBP1 (0.945); SIC1 (0.942); SWI6 (0.929); HCM1 (0.925); ASH1 (0.898); PCL2 (0.874); MOB2 (0.869); CLB3 (0.868)
Homologues (species, bitscore): KLF14 (Homo sapiens, 83.2); Klf16 (Mus musculus, 84.0); klf11b (Danio rerio, 82.8); klf11 (Xenopus tropicalis, 80.1); cbt (Drosophila melanogaster, 71.6); sptf-2 (Caenorhabditis elegans, 73.6); IDD5 (Arabidopsis thaliana, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:719564-721693:- | gene-YDR146C_AKU4011 | rna-NM_001180453.1_AKU4011 | cds-NP_010430.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:403178-405307:+ | gene-YDR146C_BG1 | rna-NM_001180453.1_BG1 | cds-NP_010430.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:751632-753761:- | gene-YDR146C_Bruggeman | rna-NM_001180453.1_Bruggeman | cds-NP_010430.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:739609-741738:- | gene-YDR146C_CAT1 | rna-NM_001180453.1_CAT1 | cds-NP_010430.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:710596-712725:- | gene-YDR146C_CBS1585 | rna-NM_001180453.1_CBS1585 | cds-NP_010430.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:736473-738602:- | gene-YDR146C_CBS436 | rna-NM_001180453.1_CBS436 | cds-NP_010430.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:706936-709065:- | gene-YDR146C_CBS6412 | rna-NM_001180453.1_CBS6412 | cds-NP_010430.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:735932-738061:- | gene-YDR146C_CBS6413 | rna-NM_001180453.1_CBS6413 | cds-NP_010430.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:741063-743192:- | gene-YDR146C_CENPK1137D | rna-NM_001180453.1_CENPK1137D | cds-NP_010430.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:721321-723450:- | gene-YDR146C_EthanolRed | rna-NM_001180453.1_EthanolRed | cds-NP_010430.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:728115-730244:- | gene-YDR146C_FaliES1 | rna-NM_001180453.1_FaliES1 | cds-NP_010430.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:80243-82372:- | gene-YDR146C_JAY291 | rna-NM_001180453.1_JAY291 | cds-NP_010430.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:737556-739685:- | gene-YDR146C_MUCL30387 | rna-NM_001180453.1_MUCL30387 | cds-NP_010430.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:726575-728704:- | gene-YDR146C_MUCL30388 | rna-NM_001180453.1_MUCL30388 | cds-NP_010430.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:711935-714064:- | gene-YDR146C_MUCL39482 | rna-NM_001180453.1_MUCL39482 | cds-NP_010430.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:649919-652048:- | gene-YDR146C_MUCL42920 | rna-NM_001180453.1_MUCL42920 | cds-NP_010430.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:748536-750665:- | gene-YDR146C_NCIM3186 | rna-NM_001180453.1_NCIM3186 | cds-NP_010430.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:711340-713469:- | gene-YDR146C_NCYC1407 | rna-NM_001180453.1_NCYC1407 | cds-NP_010430.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:730685-732814:- | gene-YDR146C_PE2H3 | rna-NM_001180453.1_PE2H3 | cds-NP_010430.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:729990-732119:- | gene-YDR146C_PE2H4 | rna-NM_001180453.1_PE2H4 | cds-NP_010430.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:748613-750742:- | gene-YDR146C_S288C | rna-NM_001180453.1_S288C | cds-NP_010430.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:97301-99430:- | gene-YDR146C_SA1 | rna-NM_001180453.1_SA1 | cds-NP_010430.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:727637-729766:- | gene-YDR146C_ThermosaccDry | rna-NM_001180453.1_ThermosaccDry | cds-NP_010430.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:741223-743352:- | gene-YDR146C_VR1 | rna-NM_001180453.1_VR1 | cds-NP_010430.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:725252-727381:- | gene-YDR146C_ZTW1 | rna-NM_001180453.1_ZTW1 | cds-NP_010430.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:729828-731957:- | gene-YDR146C_Sparadoxus | rna-NM_001180453.1_Sparadoxus | cds-NP_010430.1_Sparadoxus | 87.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |