SWI3 (YJL176C)


Gene profile

Gene name: SWI3
Reference locus (S288C): YJL176C
Gene biotype: protein_coding

Description: Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; contains SANT domain that is required for SWI/SNF assembly; is essential for displacement of histone H2A-H2B dimers during ATP-dependent remodeling; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions

Top 10 interactors (score): SNF5 (0.999); ARP9 (0.999); SNF6 (0.999); ARP7 (0.999); SWI1 (0.999); SWP82 (0.999); SNF12 (0.999); SNF2 (0.999); RTT102 (0.996); TAF14 (0.994); ARP4 (0.993); SNF11 (0.993); STH1 (0.984); RSC6 (0.972); RSC1 (0.963); RSC2 (0.952); SFH1 (0.91); GCN5 (0.902); HHT1 (0.863); HHT2 (0.86)

Homologues (species, bitscore): SMARCC2 (Homo sapiens, 236.1); Smarcc2 (Mus musculus, 233.4); smarcc1a (Danio rerio, 235.7); smarcc2 (Xenopus tropicalis, 242.3); mor (Drosophila melanogaster, 236.5); swsn-1 (Caenorhabditis elegans, 250.8); SWI3B (Arabidopsis thaliana, 149.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:80447-82924:- gene-YJL176C_AKU4011 rna-NM_001181609.1_AKU4011 cds-NP_012359.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000181.1:57782-60259:- gene-YJL176C_BG1 rna-NM_001181609.1_BG1 cds-NP_012359.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:92278-94755:- gene-YJL176C_Bruggeman rna-NM_001181609.1_Bruggeman cds-NP_012359.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:95747-98224:- gene-YJL176C_CAT1 rna-NM_001181609.1_CAT1 cds-NP_012359.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:86082-88559:- gene-YJL176C_CBS1585 rna-NM_001181609.1_CBS1585 cds-NP_012359.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:110843-113320:- gene-YJL176C_CBS436 rna-NM_001181609.1_CBS436 cds-NP_012359.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:82564-85041:- gene-YJL176C_CBS6412 rna-NM_001181609.1_CBS6412 cds-NP_012359.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:83557-86034:- gene-YJL176C_CBS6413 rna-NM_001181609.1_CBS6413 cds-NP_012359.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:74529-77006:- gene-YJL176C_CENPK1137D rna-NM_001181609.1_CENPK1137D cds-NP_012359.1_CENPK1137D 99.1 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:84743-87220:- gene-YJL176C_EthanolRed rna-NM_001181609.1_EthanolRed cds-NP_012359.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:90020-92497:- gene-YJL176C_FaliES1 rna-NM_001181609.1_FaliES1 cds-NP_012359.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000164.1:26228-28705:+ gene-YJL176C_JAY291 rna-NM_001181609.1_JAY291 cds-NP_012359.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:94006-96483:- gene-YJL176C_MUCL30387 rna-NM_001181609.1_MUCL30387 cds-NP_012359.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:90167-92644:- gene-YJL176C_MUCL30388 rna-NM_001181609.1_MUCL30388 cds-NP_012359.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:84823-87300:- gene-YJL176C_MUCL39482 rna-NM_001181609.1_MUCL39482 cds-NP_012359.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:89435-91912:- gene-YJL176C_MUCL42920 rna-NM_001181609.1_MUCL42920 cds-NP_012359.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:92032-94509:- gene-YJL176C_NCIM3186 rna-NM_001181609.1_NCIM3186 cds-NP_012359.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:83435-85912:- gene-YJL176C_NCYC1407 rna-NM_001181609.1_NCYC1407 cds-NP_012359.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:96148-98625:- gene-YJL176C_PE2H3 rna-NM_001181609.1_PE2H3 cds-NP_012359.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:95787-98264:- gene-YJL176C_PE2H4 rna-NM_001181609.1_PE2H4 cds-NP_012359.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:92053-94530:- gene-YJL176C_S288C rna-NM_001181609.1_S288C cds-NP_012359.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000022.1:59340-61817:+ gene-YJL176C_SA1 rna-NM_001181609.1_SA1 cds-NP_012359.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:83214-85691:- gene-YJL176C_ThermosaccDry rna-NM_001181609.1_ThermosaccDry cds-NP_012359.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:90099-92576:- gene-YJL176C_VR1 rna-NM_001181609.1_VR1 cds-NP_012359.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:70798-73275:- gene-YJL176C_ZTW1 rna-NM_001181609.1_ZTW1 cds-NP_012359.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:95200-97659:- gene-YJL176C_Sparadoxus rna-NM_001181609.1_Sparadoxus cds-NP_012359.1_Sparadoxus 87.5 99.1 Verified 1 1 1 False True False False False

Additional files