SWI1 (YPL016W)


Gene profile

Gene name: SWI1
Reference locus (S288C): YPL016W
Gene biotype: protein_coding

Description: Subunit of the SWI/SNF chromatin remodeling complex; regulates transcription by remodeling chromatin; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; self-assembles to form [SWI+] prion and to alter expression pattern; human homolog ARID1A is a candidate tumor suppressor gene in breast cancer; Belongs to the SWI1 family

Top 10 interactors (score): SNF6 (0.999); SNF2 (0.999); SNF12 (0.999); ARP9 (0.999); SNF5 (0.999); SWI3 (0.999); ARP7 (0.999); SWP82 (0.998); RTT102 (0.997); TAF14 (0.991); SNF11 (0.989); HHT2 (0.961); HTB1 (0.955); SUP35 (0.95); SPT2 (0.947); URE2 (0.935); CYC8 (0.922); HTB2 (0.92); SIN3 (0.919); RNQ1 (0.919)

Homologues (species, bitscore): ARID5B (Homo sapiens, 57.4); Kmt2d (Mus musculus, 74.3); arid5a (Danio rerio, 58.9); arid5b (Xenopus tropicalis, 56.6); CG34422 (Drosophila melanogaster, 53.5); let-526 (Caenorhabditis elegans, 62.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:492495-496433:+ gene-YPL016W_AKU4011 rna-NM_001183830.2_AKU4011 cds-NP_015309.1_AKU4011 95.9 98.2 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:400874-404835:- gene-YPL016W_BG1 rna-NM_001183830.2_BG1 cds-NP_015309.1_BG1 95.8 98.4 Verified 1 1 0 False False True False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:569428-573384:+ gene-YPL016W_Bruggeman rna-NM_001183830.2_Bruggeman cds-NP_015309.1_Bruggeman 97.9 99.3 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:611863-615822:+ gene-YPL016W_CAT1 rna-NM_001183830.2_CAT1 cds-NP_015309.1_CAT1 98.1 99.3 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:496567-500595:+ gene-YPL016W_CBS1585 rna-NM_001183830.2_CBS1585 cds-NP_015309.1_CBS1585 96.3 99.9 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:510690-514649:+ gene-YPL016W_CBS436 rna-NM_001183830.2_CBS436 cds-NP_015309.1_CBS436 98.1 99.3 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:500411-504347:+ gene-YPL016W_CBS6412 rna-NM_001183830.2_CBS6412 cds-NP_015309.1_CBS6412 90.2 95.9 Unannotated 1 1 0 False False True False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:493120-497070:+ gene-YPL016W_CBS6413 rna-NM_001183830.2_CBS6413 cds-NP_015309.1_CBS6413 95.9 98.3 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:520952-524965:+ gene-YPL016W_CENPK1137D rna-NM_001183830.2_CENPK1137D cds-NP_015309.1_CENPK1137D 97.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:490844-494854:+ gene-YPL016W_EthanolRed rna-NM_001183830.2_EthanolRed cds-NP_015309.1_EthanolRed 96.9 99.6 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:498674-502684:+ gene-YPL016W_FaliES1 rna-NM_001183830.2_FaliES1 cds-NP_015309.1_FaliES1 97.4 99.9 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:107290-111243:+ gene-YPL016W_JAY291 rna-NM_001183830.2_JAY291 cds-NP_015309.1_JAY291 98.3 99.3 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:510377-514333:+ gene-YPL016W_MUCL30387 rna-NM_001183830.2_MUCL30387 cds-NP_015309.1_MUCL30387 97.9 99.3 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:509485-513441:+ gene-YPL016W_MUCL30388 rna-NM_001183830.2_MUCL30388 cds-NP_015309.1_MUCL30388 98.0 99.3 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:489885-493835:+ gene-YPL016W_MUCL39482 rna-NM_001183830.2_MUCL39482 cds-NP_015309.1_MUCL39482 95.9 98.4 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:549008-552925:+ gene-YPL016W_MUCL42920 rna-NM_001183830.2_MUCL42920 cds-NP_015309.1_MUCL42920 98.9 99.3 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:520997-524941:+ gene-YPL016W_NCIM3186 rna-NM_001183830.2_NCIM3186 cds-NP_015309.1_NCIM3186 98.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:497159-501109:+ gene-YPL016W_NCYC1407 rna-NM_001183830.2_NCYC1407 cds-NP_015309.1_NCYC1407 96.0 98.4 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:503817-507770:+ gene-YPL016W_PE2H3 rna-NM_001183830.2_PE2H3 cds-NP_015309.1_PE2H3 98.3 99.3 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:503432-507385:+ gene-YPL016W_PE2H4 rna-NM_001183830.2_PE2H4 cds-NP_015309.1_PE2H4 98.3 99.3 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:521014-524958:+ gene-YPL016W_S288C rna-NM_001183830.2_S288C cds-NP_015309.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000076.1:17683-21672:+ gene-YPL016W_SA1 rna-NM_001183830.2_SA1 cds-NP_015309.1_SA1 96.4 99.1 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:498473-502483:+ gene-YPL016W_ThermosaccDry rna-NM_001183830.2_ThermosaccDry cds-NP_015309.1_ThermosaccDry 97.4 99.9 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:513623-517870:+ gene-YPL016W_VR1 rna-NM_001183830.2_VR1 cds-NP_015309.1_VR1 91.4 99.3 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:497759-501769:+ gene-YPL016W_ZTW1 rna-NM_001183830.2_ZTW1 cds-NP_015309.1_ZTW1 97.5 99.9 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:497683-501637:+ gene-YPL016W_Sparadoxus rna-NM_001183830.2_Sparadoxus cds-NP_015309.1_Sparadoxus 86.2 98.3 Unannotated 1 1 0 False False True False False

Additional files