Gene name: SWI1
Reference locus (S288C): YPL016W
Gene biotype: protein_coding
Description: Subunit of the SWI/SNF chromatin remodeling complex; regulates transcription by remodeling chromatin; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; self-assembles to form [SWI+] prion and to alter expression pattern; human homolog ARID1A is a candidate tumor suppressor gene in breast cancer; Belongs to the SWI1 family
Top 10 interactors (score): SNF6 (0.999); SNF2 (0.999); SNF12 (0.999); ARP9 (0.999); SNF5 (0.999); SWI3 (0.999); ARP7 (0.999); SWP82 (0.998); RTT102 (0.997); TAF14 (0.991); SNF11 (0.989); HHT2 (0.961); HTB1 (0.955); SUP35 (0.95); SPT2 (0.947); URE2 (0.935); CYC8 (0.922); HTB2 (0.92); SIN3 (0.919); RNQ1 (0.919)
Homologues (species, bitscore): ARID5B (Homo sapiens, 57.4); Kmt2d (Mus musculus, 74.3); arid5a (Danio rerio, 58.9); arid5b (Xenopus tropicalis, 56.6); CG34422 (Drosophila melanogaster, 53.5); let-526 (Caenorhabditis elegans, 62.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:492495-496433:+ | gene-YPL016W_AKU4011 | rna-NM_001183830.2_AKU4011 | cds-NP_015309.1_AKU4011 | 95.9 | 98.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:400874-404835:- | gene-YPL016W_BG1 | rna-NM_001183830.2_BG1 | cds-NP_015309.1_BG1 | 95.8 | 98.4 | Verified | 1 | 1 | 0 | False | False | True | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:569428-573384:+ | gene-YPL016W_Bruggeman | rna-NM_001183830.2_Bruggeman | cds-NP_015309.1_Bruggeman | 97.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:611863-615822:+ | gene-YPL016W_CAT1 | rna-NM_001183830.2_CAT1 | cds-NP_015309.1_CAT1 | 98.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:496567-500595:+ | gene-YPL016W_CBS1585 | rna-NM_001183830.2_CBS1585 | cds-NP_015309.1_CBS1585 | 96.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:510690-514649:+ | gene-YPL016W_CBS436 | rna-NM_001183830.2_CBS436 | cds-NP_015309.1_CBS436 | 98.1 | 99.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:500411-504347:+ | gene-YPL016W_CBS6412 | rna-NM_001183830.2_CBS6412 | cds-NP_015309.1_CBS6412 | 90.2 | 95.9 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:493120-497070:+ | gene-YPL016W_CBS6413 | rna-NM_001183830.2_CBS6413 | cds-NP_015309.1_CBS6413 | 95.9 | 98.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:520952-524965:+ | gene-YPL016W_CENPK1137D | rna-NM_001183830.2_CENPK1137D | cds-NP_015309.1_CENPK1137D | 97.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:490844-494854:+ | gene-YPL016W_EthanolRed | rna-NM_001183830.2_EthanolRed | cds-NP_015309.1_EthanolRed | 96.9 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:498674-502684:+ | gene-YPL016W_FaliES1 | rna-NM_001183830.2_FaliES1 | cds-NP_015309.1_FaliES1 | 97.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:107290-111243:+ | gene-YPL016W_JAY291 | rna-NM_001183830.2_JAY291 | cds-NP_015309.1_JAY291 | 98.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:510377-514333:+ | gene-YPL016W_MUCL30387 | rna-NM_001183830.2_MUCL30387 | cds-NP_015309.1_MUCL30387 | 97.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:509485-513441:+ | gene-YPL016W_MUCL30388 | rna-NM_001183830.2_MUCL30388 | cds-NP_015309.1_MUCL30388 | 98.0 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:489885-493835:+ | gene-YPL016W_MUCL39482 | rna-NM_001183830.2_MUCL39482 | cds-NP_015309.1_MUCL39482 | 95.9 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:549008-552925:+ | gene-YPL016W_MUCL42920 | rna-NM_001183830.2_MUCL42920 | cds-NP_015309.1_MUCL42920 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:520997-524941:+ | gene-YPL016W_NCIM3186 | rna-NM_001183830.2_NCIM3186 | cds-NP_015309.1_NCIM3186 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:497159-501109:+ | gene-YPL016W_NCYC1407 | rna-NM_001183830.2_NCYC1407 | cds-NP_015309.1_NCYC1407 | 96.0 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:503817-507770:+ | gene-YPL016W_PE2H3 | rna-NM_001183830.2_PE2H3 | cds-NP_015309.1_PE2H3 | 98.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:503432-507385:+ | gene-YPL016W_PE2H4 | rna-NM_001183830.2_PE2H4 | cds-NP_015309.1_PE2H4 | 98.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:521014-524958:+ | gene-YPL016W_S288C | rna-NM_001183830.2_S288C | cds-NP_015309.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000076.1:17683-21672:+ | gene-YPL016W_SA1 | rna-NM_001183830.2_SA1 | cds-NP_015309.1_SA1 | 96.4 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:498473-502483:+ | gene-YPL016W_ThermosaccDry | rna-NM_001183830.2_ThermosaccDry | cds-NP_015309.1_ThermosaccDry | 97.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:513623-517870:+ | gene-YPL016W_VR1 | rna-NM_001183830.2_VR1 | cds-NP_015309.1_VR1 | 91.4 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:497759-501769:+ | gene-YPL016W_ZTW1 | rna-NM_001183830.2_ZTW1 | cds-NP_015309.1_ZTW1 | 97.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:497683-501637:+ | gene-YPL016W_Sparadoxus | rna-NM_001183830.2_Sparadoxus | cds-NP_015309.1_Sparadoxus | 86.2 | 98.3 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |