Gene name: SWH1
Reference locus (S288C): YAR042W
Gene biotype: protein_coding
Description: Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication; Belongs to the OSBP family
Top 10 interactors (score): NVJ1 (0.996); SCS2 (0.992); SAC1 (0.886); AGE2 (0.883); STT4 (0.864); VAC8 (0.857); OPI1 (0.822); TSC13 (0.822); INO1 (0.78); KES1 (0.762); YPR089W (0.748); TPH3 (0.745); YPT7 (0.743); PAH1 (0.74); AFG2 (0.735); SEC14 (0.683); HES1 (0.682); JIP4 (0.677); YMR099C (0.676); LSB6 (0.676)
Homologues (species, bitscore): OSBP (Homo sapiens, 307.0); Osbp (Mus musculus, 310.5); osbp (Danio rerio, 297.4); osbp (Xenopus tropicalis, 282.7); Osbp (Drosophila melanogaster, 288.5); obr-1 (Caenorhabditis elegans, 263.1); ORP2B (Arabidopsis thaliana, 279.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:176417-179989:+ | gene-YAR042W_AKU4011 | rna-NM_001178227.1_AKU4011 | cds-NP_009421.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000097.1:7324-10890:- | gene-YAR042W_BG1 | rna-NM_001178227.1_BG1 | cds-NP_009421.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:189410-192976:+ | gene-YAR042W_Bruggeman | rna-NM_001178227.1_Bruggeman | cds-NP_009421.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:179383-182955:+ | gene-YAR042W_CAT1 | rna-NM_001178227.1_CAT1 | cds-NP_009421.3_CAT1 | 98.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:187605-191168:+ | gene-YAR042W_CBS1585 | rna-NM_001178227.1_CBS1585 | cds-NP_009421.3_CBS1585 | 99.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:185241-188807:+ | gene-YAR042W_CBS436 | rna-NM_001178227.1_CBS436 | cds-NP_009421.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:222357-225920:+ | gene-YAR042W_CBS6412 | rna-NM_001178227.1_CBS6412 | cds-NP_009421.3_CBS6412 | 99.2 | 99.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:183862-187434:+ | gene-YAR042W_CBS6413 | rna-NM_001178227.1_CBS6413 | cds-NP_009421.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:192571-196143:+ | gene-YAR042W_CENPK1137D | rna-NM_001178227.1_CENPK1137D | cds-NP_009421.3_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:173445-177008:+ | gene-YAR042W_EthanolRed | rna-NM_001178227.1_EthanolRed | cds-NP_009421.3_EthanolRed | 99.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:191070-194633:+ | gene-YAR042W_FaliES1 | rna-NM_001178227.1_FaliES1 | cds-NP_009421.3_FaliES1 | 99.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000016.1:3038-6604:+ | gene-YAR042W_JAY291 | rna-NM_001178227.1_JAY291 | cds-NP_009421.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:191900-195463:+ | gene-YAR042W_MUCL30387 | rna-NM_001178227.1_MUCL30387 | cds-NP_009421.3_MUCL30387 | 99.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:192041-196361:+ | gene-YAR042W_MUCL30388 | rna-NM_001178227.1_MUCL30388 | cds-NP_009421.3_MUCL30388 | 82.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:183250-186822:+ | gene-YAR042W_MUCL39482 | rna-NM_001178227.1_MUCL39482 | cds-NP_009421.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:184070-187636:+ | gene-YAR042W_MUCL42920 | rna-NM_001178227.1_MUCL42920 | cds-NP_009421.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:192496-196062:+ | gene-YAR042W_NCIM3186 | rna-NM_001178227.1_NCIM3186 | cds-NP_009421.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:170390-173962:+ | gene-YAR042W_NCYC1407 | rna-NM_001178227.1_NCYC1407 | cds-NP_009421.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:179982-183548:+ | gene-YAR042W_PE2H3 | rna-NM_001178227.1_PE2H3 | cds-NP_009421.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:179701-183267:+ | gene-YAR042W_PE2H4 | rna-NM_001178227.1_PE2H4 | cds-NP_009421.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:192619-196185:+ | gene-YAR042W_S288C | rna-NM_001178227.1_S288C | cds-NP_009421.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000116.1:9520-13086:- | gene-YAR042W_SA1 | rna-NM_001178227.1_SA1 | cds-NP_009421.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:401836-405399:+ | gene-YAR042W_ThermosaccDry | rna-NM_001178227.1_ThermosaccDry | cds-NP_009421.3_ThermosaccDry | 99.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:199461-203021:+ | gene-YAR042W_VR1 | rna-NM_001178227.1_VR1 | cds-NP_009421.3_VR1 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:163669-167250:+ | gene-YAR042W_ZTW1 | rna-NM_001178227.1_ZTW1 | cds-NP_009421.3_ZTW1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:182874-186422:+ | gene-YAR042W_Sparadoxus | rna-NM_001178227.1_Sparadoxus | cds-NP_009421.3_Sparadoxus | 89.5 | 98.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |