Gene name: SWD3
Reference locus (S288C): YBR175W
Gene biotype: protein_coding
Description: COMPASS component SWD3; Essential subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5
Top 10 interactors (score): SDC1 (0.999); SWD2 (0.999); BRE2 (0.999); SET1 (0.999); SPP1 (0.999); SWD1 (0.999); SHG1 (0.998); CYC8 (0.996); RTT107 (0.993); UBI4 (0.992); RPS31 (0.992); GCN5 (0.991); SET2 (0.982); ESA1 (0.981); SAS3 (0.981); BRE1 (0.981); ADA2 (0.971); RPL40A (0.968); RPL40B (0.968); RVB1 (0.966)
Homologues (species, bitscore): WDR5 (Homo sapiens, 158.7); Wdr5b (Mus musculus, 159.5); wdr5 (Danio rerio, 156.0); wdr5 (Xenopus tropicalis, 156.8); wds (Drosophila melanogaster, 154.1); wdr-5.1 (Caenorhabditis elegans, 159.5); WDR5a (Arabidopsis thaliana, 147.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:565280-566227:+ | gene-YBR175W_AKU4011 | rna-NM_001178523.1_AKU4011 | cds-NP_009734.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:555786-556733:+ | gene-YBR175W_BG1 | rna-NM_001178523.1_BG1 | cds-NP_009734.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:568303-569250:+ | gene-YBR175W_Bruggeman | rna-NM_001178523.1_Bruggeman | cds-NP_009734.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:462413-463360:+ | gene-YBR175W_CAT1 | rna-NM_001178523.1_CAT1 | cds-NP_009734.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:557061-558008:+ | gene-YBR175W_CBS1585 | rna-NM_001178523.1_CBS1585 | cds-NP_009734.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:565139-566086:+ | gene-YBR175W_CBS436 | rna-NM_001178523.1_CBS436 | cds-NP_009734.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:654546-655493:+ | gene-YBR175W_CBS6412 | rna-NM_001178523.1_CBS6412 | cds-NP_009734.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:562617-563564:+ | gene-YBR175W_CBS6413 | rna-NM_001178523.1_CBS6413 | cds-NP_009734.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:576205-577152:+ | gene-YBR175W_CENPK1137D | rna-NM_001178523.1_CENPK1137D | cds-NP_009734.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:691122-692069:+ | gene-YBR175W_EthanolRed | rna-NM_001178523.1_EthanolRed | cds-NP_009734.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:581354-582301:+ | gene-YBR175W_FaliES1 | rna-NM_001178523.1_FaliES1 | cds-NP_009734.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000310.1:21184-22131:+ | gene-YBR175W_JAY291 | rna-NM_001178523.1_JAY291 | cds-NP_009734.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:569956-570903:+ | gene-YBR175W_MUCL30387 | rna-NM_001178523.1_MUCL30387 | cds-NP_009734.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:569242-570189:+ | gene-YBR175W_MUCL30388 | rna-NM_001178523.1_MUCL30388 | cds-NP_009734.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:555434-556381:+ | gene-YBR175W_MUCL39482 | rna-NM_001178523.1_MUCL39482 | cds-NP_009734.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:565358-566305:+ | gene-YBR175W_MUCL42920 | rna-NM_001178523.1_MUCL42920 | cds-NP_009734.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:582205-583152:+ | gene-YBR175W_NCIM3186 | rna-NM_001178523.1_NCIM3186 | cds-NP_009734.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:558004-558951:+ | gene-YBR175W_NCYC1407 | rna-NM_001178523.1_NCYC1407 | cds-NP_009734.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:570658-571605:+ | gene-YBR175W_PE2H3 | rna-NM_001178523.1_PE2H3 | cds-NP_009734.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:568334-569281:+ | gene-YBR175W_PE2H4 | rna-NM_001178523.1_PE2H4 | cds-NP_009734.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:582408-583355:+ | gene-YBR175W_S288C | rna-NM_001178523.1_S288C | cds-NP_009734.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:103650-104597:+ | gene-YBR175W_SA1 | rna-NM_001178523.1_SA1 | cds-NP_009734.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:580364-581311:+ | gene-YBR175W_ThermosaccDry | rna-NM_001178523.1_ThermosaccDry | cds-NP_009734.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:561809-562756:+ | gene-YBR175W_VR1 | rna-NM_001178523.1_VR1 | cds-NP_009734.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:555479-556426:+ | gene-YBR175W_ZTW1 | rna-NM_001178523.1_ZTW1 | cds-NP_009734.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:592833-593780:+ | gene-YBR175W_Sparadoxus | rna-NM_001178523.1_Sparadoxus | cds-NP_009734.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |