Gene name: SWD2
Reference locus (S288C): YKL018W
Gene biotype: protein_coding
Description: Wd-repeat containing protein swd2; COMPASS component SWD2; Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex; required for Set1C stability and optimal activity; COMPASS methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination; Belongs to the WD repeat SWD2 family
Top 10 interactors (score): YSH1 (0.999); GLC7 (0.999); SWD3 (0.999); PTA1 (0.999); PAP1 (0.999); PTI1 (0.999); REF2 (0.999); SYC1 (0.999); CFT2 (0.999); BRE2 (0.999); CFT1 (0.999); PFS2 (0.999); SSU72 (0.999); YTH1 (0.999); SPP1 (0.999); SWD1 (0.999); SET1 (0.999); MPE1 (0.999); FIP1 (0.999); SDC1 (0.998)
Homologues (species, bitscore): WDR82 (Homo sapiens, 174.5); Wdr82 (Mus musculus, 174.5); wdr82 (Danio rerio, 178.3); wdr82 (Xenopus tropicalis, 172.2); Wdr82 (Drosophila melanogaster, 179.1); swd-2.2 (Caenorhabditis elegans, 138.7); AT5G14530 (Arabidopsis thaliana, 153.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:390119-391108:+ | gene-YKL018W_AKU4011 | rna-NM_001179584.3_AKU4011 | cds-NP_012907.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:252796-253785:- | gene-YKL018W_BG1 | rna-NM_001179584.3_BG1 | cds-NP_012907.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:411822-412811:+ | gene-YKL018W_Bruggeman | rna-NM_001179584.3_Bruggeman | cds-NP_012907.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:406930-407919:+ | gene-YKL018W_CAT1 | rna-NM_001179584.3_CAT1 | cds-NP_012907.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:402839-403828:+ | gene-YKL018W_CBS1585 | rna-NM_001179584.3_CBS1585 | cds-NP_012907.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:401700-402689:+ | gene-YKL018W_CBS436 | rna-NM_001179584.3_CBS436 | cds-NP_012907.3_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:386995-387984:+ | gene-YKL018W_CBS6412 | rna-NM_001179584.3_CBS6412 | cds-NP_012907.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:402694-403683:+ | gene-YKL018W_CBS6413 | rna-NM_001179584.3_CBS6413 | cds-NP_012907.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:403779-404768:+ | gene-YKL018W_CENPK1137D | rna-NM_001179584.3_CENPK1137D | cds-NP_012907.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:400616-401605:+ | gene-YKL018W_EthanolRed | rna-NM_001179584.3_EthanolRed | cds-NP_012907.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:402706-403695:+ | gene-YKL018W_FaliES1 | rna-NM_001179584.3_FaliES1 | cds-NP_012907.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000142.1:27355-28344:- | gene-YKL018W_JAY291 | rna-NM_001179584.3_JAY291 | cds-NP_012907.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:411137-412126:+ | gene-YKL018W_MUCL30387 | rna-NM_001179584.3_MUCL30387 | cds-NP_012907.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:406746-407735:+ | gene-YKL018W_MUCL30388 | rna-NM_001179584.3_MUCL30388 | cds-NP_012907.3_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:402156-403145:+ | gene-YKL018W_MUCL39482 | rna-NM_001179584.3_MUCL39482 | cds-NP_012907.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:407983-408972:+ | gene-YKL018W_MUCL42920 | rna-NM_001179584.3_MUCL42920 | cds-NP_012907.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:404091-405080:+ | gene-YKL018W_NCIM3186 | rna-NM_001179584.3_NCIM3186 | cds-NP_012907.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:402348-403337:+ | gene-YKL018W_NCYC1407 | rna-NM_001179584.3_NCYC1407 | cds-NP_012907.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:427038-428027:+ | gene-YKL018W_PE2H3 | rna-NM_001179584.3_PE2H3 | cds-NP_012907.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:411782-412771:+ | gene-YKL018W_PE2H4 | rna-NM_001179584.3_PE2H4 | cds-NP_012907.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:404102-405091:+ | gene-YKL018W_S288C | rna-NM_001179584.3_S288C | cds-NP_012907.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:82380-83369:+ | gene-YKL018W_SA1 | rna-NM_001179584.3_SA1 | cds-NP_012907.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:402805-403794:+ | gene-YKL018W_ThermosaccDry | rna-NM_001179584.3_ThermosaccDry | cds-NP_012907.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:402059-403048:+ | gene-YKL018W_VR1 | rna-NM_001179584.3_VR1 | cds-NP_012907.3_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:400833-401822:+ | gene-YKL018W_ZTW1 | rna-NM_001179584.3_ZTW1 | cds-NP_012907.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:425827-426816:+ | gene-YKL018W_Sparadoxus | rna-NM_001179584.3_Sparadoxus | cds-NP_012907.3_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |